A modified acetic anhydride-sulphuric acid color test for oils

1973 ◽  
Vol 50 (12) ◽  
pp. 545-546
Author(s):  
G. Azeemoddin ◽  
S. D. Thirumala Rao ◽  
B. R. Reddy
Keyword(s):  
Acetic Anhydride ◽  
Sulphuric Acid ◽  
Color Test ◽  
Acid Color

REACTIONS OF PHENYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS: V. NITRATIONS OF 1,3- AND 1,5-DIPHENYLPYRAZOLES

1964 ◽  
Vol 42 (7) ◽  
pp. 1605-1615 ◽  
Author(s):  
Brian M. Lynch ◽  
Yuic-Yung Hung
Keyword(s):  
Nitric Acid ◽  
Magnetic Resonance ◽  
Acetic Anhydride ◽  
Sulphuric Acid ◽  
Heterocyclic Compounds ◽  
Substituted 1

Dinitration of 1,3- or 1,5-diphenylpyrazole in sulphuric acid yields the corresponding di(p-nitrophenyl) compounds, while nitric acid–acetic anhydride yields the 4-nitro-1-p-nitrophenyl compounds.Mononitration at the 4-position occurs when the diphenylpyrazoles and several other 1-phenylpyrazoles are nitrated at 0° by nitric acid–acetic anhydride.Possible explanations of the dependence of orientation on the nature of the nitrating agent-are discussed.Nuclear magnetic resonance (n.m.r.) spectroscopy was used in demonstrating the structures of many of the nitration products, and a general discussion of the n.m.r. spectra of substituted 1-phenylpyrazoles is given.

Cyclic nitrones. II. Reactions of a cyclic α-keto nitrone with acetic anhydride, acetone, and methyl acetoacetate

1967 ◽  
Vol 20 (11) ◽  
pp. 2485 ◽  
Author(s):  
RFC Brown ◽  
WD Crow ◽  
L Subrahmanyan ◽  
CS Barnes
Keyword(s):  
Acetic Anhydride ◽  
Sulphuric Acid ◽  
Functional Groups ◽  
Potassium Hydroxide ◽  
Methyl Acetoacetate ◽  
Cyclic Nitrones ◽  
Aqueous Potassium Hydroxide ◽  
Isopropenyl Acetate

The cyclic α-keto nitrone 3,4,5,6-tetrahydro-5,5-dimethyl-3-oxopyridine 1-oxide (III) when treated with acetic anhydride and sulphuric acid gave in low yield a compound (XI) having both enol lactone and vinylogous amide functional groups. Hydrolysis and decarboxylation of compound (XI) with aqueous potassium hydroxide gave a vinylogous amide (V), also obtained by acid- or base-catalysed condensation of compound (III) with isopropenyl acetate or acetone. Base-catalysed condensation of (III) with methyl acetoacetate gave an ester (XVII) closely related to compound (V).

The Acetic Anhydride-Sulphuric Reaction for General Paresis

1927 ◽  
Vol 73 (302) ◽  
pp. 419-421 ◽  
Author(s):  
A. G. Duncan
Keyword(s):  
Acetic Anhydride ◽  
Mental Disorder ◽  
Sulphuric Acid ◽  
Positive Reaction ◽  
Chemical Reaction ◽  
Spinal Fluid ◽  
General Paresis ◽  
Simple Chemical

While elaborating a test for cholesterol in the cerebro-spinal fluid, 0. H. Boltz (I) observed and investigated a reaction which occurred predominantly in cases of neuro-syphilis, and which he named the acetic anhydride-sulphuric test. To I c.c. of spinal fluid was added 03 c.c. of acetic anhydride, drop by drop, and after mixing the fluids by shaking, [email protected]. of concentrated sulphuric acid was added in drops, and the mixture shaken again. The development of a blue pink or lilac colour characterized a positive reaction. The test has been studied in this country, and it has been claimed that the reaction is positive in almost every case of general paresis, and negative in almost every other type of mental disorder, except certain cases of non-paretic neuro-syphilis. As this constitutes a surprising degree of specificity of an apparently simple chemical reaction for a single disease, I have carried out the reaction in association with the routine tests in a series of cerebro-spinal fluids with a view to ascertaining its value. One hundred and sixty fluids were examined—a comparatively small number on which to base conclusions, but the results will show that the claims previously advanced for the value of the test require considerable modification.

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