Regional determination of ATP, glucose and lactate in cervical-cancer biopsies

1995 ◽  
Vol 121 (S1) ◽  
pp. A71-A71
Author(s):  
G. Schwickert ◽  
S. Walenta ◽  
W. Mueller-Klieser ◽  
E. K. Rofstad
In Extremis ◽  
2010 ◽  
pp. 90-102
Author(s):  
Paul Dostal ◽  
Florian Imbery ◽  
Katrin Bürger ◽  
Jochen Seidel

1972 ◽  
Vol 11 (61) ◽  
pp. 73-79 ◽  
Author(s):  
R. E. Dugdale

AbstractData from Norwegian glaciers and statistical tests are presented which suggest that vertical net-budget gradient, ablation gradient and equilibrium-line altitude can be taken as characteristic for any particular glacier. The usefulness of these conceptual models as predictive techniques for the regional determination of glacier net budget when only a small sample is available, and in palaeo-net-budget studies, is shown to be limited.


2011 ◽  
Vol 24 (10) ◽  
pp. 1253-1263 ◽  
Author(s):  
Stephen Kadlecek ◽  
Puttisarn Mongkolwisetwara ◽  
Yi Xin ◽  
Masaru Ishii ◽  
Harilla Profka ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Kouji Banno ◽  
Miho Iida ◽  
Megumi Yanokura ◽  
Iori Kisu ◽  
Takashi Iwata ◽  
...  

Cervical cancer is a female-specific disease with a high incidence and mortality. MicroRNAs (miRNAs) are implicated in posttranscriptional regulation of gene expression and in the pathogenic mechanisms of cancer, suggesting their importance in diagnosis and treatment. miRNAs may have roles in the pathogenesis of cervical cancer based on the increases or decreases in several specific miRNAs found in patients with this disease. The miRNAs implicated in cervical cancer are miR-21, miR-126, and miR-143, and clinical application of these miRNAs for diagnosis and treatment is under investigation. Methods for diagnosis of cervical cancer include analysis of changes in the levels of specific miRNAs in serum and determination of aberrant hypermethylation of miRNAs. Supplementation of miR-143 or inhibition of miR-21 activityin vivomay be therapeutic strategy for cervical cancer. Previous approaches to development of siRNA as a drug have provided information for establishment of therapy based on these approaches, and an anti-miR-21 inhibitor has been developed. miRNAs also have effects on drug resistance and may be useful in combination therapy with other drugs.


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