Comparative effects of glycopyrrolate, atropine sulfate and propantheline bromide on canine parietal cell ultrastructure

1970 ◽  
Vol 15 (12) ◽  
pp. 1091-1098 ◽  
Author(s):  
E. Leonard Posey ◽  
R. Keith Boler ◽  
Leonard Posey
1982 ◽  
Vol 27 (5) ◽  
pp. 394-400
Author(s):  
Kevin J. Ivey ◽  
Andrzej Tarnawski ◽  
William J. Krause ◽  
Jerzy Stachura ◽  
Debra Sherman ◽  
...  

1969 ◽  
Vol 47 (4) ◽  
pp. 402-405
Author(s):  
K. Kowalewski

An anticholinergic drug, propantheline bromide, was given to rats in a dosage of 5 mg/kg body weight twice daily, for 6, 9, or 12 months. Parietal cell mass was determined in these animals and in controls of similar age and weight. A significant decrease in the number of parietal cells was found in the stomachs of treated rats. This was considered to represent an "inhibition hypoplasia" produced experimentally.


Author(s):  
Burton B. Silver ◽  
Theodore Lawwill

Dutch-belted 1 to 2.5 kg anesthetized rabbits were exposed to either xenon or argon laser light administered in a broad band, designed to cover large areas of the retina. For laser exposure, the pupil was dilated with atropine sulfate 1% and pheny lephrine 10%. All of the laser generated power was within a band centered at 5145.0 Anstroms. Established threshold for 4 hour exposures to laser irradiation are in the order of 25-35 microwatts/cm2. Animals examined for ultrastructural changes received 4 hour threshold doses. These animals exhibited ERG, opthalmascopic, and histological changes consistent with threshold damage.One month following exposure the rabbits were killed with pentobarbitol. The eyes were immediately enucleated and dissected while bathed in 3% phosphate buffered gluteraldehyde.


Author(s):  
D.A. Palmer ◽  
C.L. Bender

Coronatine is a non-host-specific phytotoxin produced by several members of the Pseudomonas syringae group of pathovars. The toxin acts as a virulence factor in P. syringae pv. tomato, allowing the organism to multiply to a higher population density and develop larger lesions than mutant strains unable to produce the toxin. The most prominent symptom observed in leaf tissue treated with coronatine is an intense spreading chlorosis; this has been attributed to a loss of chlorophylls a and b in tobacco. Coronatine's effects on membrane integrity and cell ultrastructure have not been previously investigated. The present study describes changes in tomato leaves in response to treatment with purified coronatine, infection by a coronatine-producing strain of P. syringae pv. tomato, and infection by a cor" mutant.In contrast to H2O-treated tissue, coronatine-treated tissue showed a diffuse chlorosis extending approximately 5 mm from the inoculation site. Leaf thickness, cell number, and cell dimensions were similar for both healthy and coronatine-treated, chlorotic tissue; however, the epidermal cell walls were consistently thicker in coronatine-treated leaves (Figs, la and lb).


2001 ◽  
Vol 120 (5) ◽  
pp. A250-A250
Author(s):  
A BARBOSA ◽  
C MENDES ◽  
L COELHO ◽  
C RODRIGUES ◽  
M MACHADO ◽  
...  

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