Smooth-pursuit eye movement dysfunction in schizophrenia: the role of attention and general psychomotor dysfunctions

1994 ◽  
Vol 244 (3) ◽  
pp. 153-160 ◽  
Author(s):  
Regine Schlenker ◽  
Rudolf Cohen ◽  
Patrick Berg ◽  
Werner Hubman ◽  
Fritz Mohr ◽  
...  
Keyword(s):  
Eye Movement ◽  
Smooth Pursuit ◽  
Smooth Pursuit Eye Movement ◽  
Eye Movement Dysfunction

95. Smooth pursuit eye movement dysfunction in patients at clinical risk for schizophrenia

2000 ◽  
Vol 47 (8) ◽  
pp. S29
Author(s):  
M. Obuchowski ◽  
T.C. Chan ◽  
E. Pappadopulos ◽  
T. Lencz ◽  
D. Coscia ◽  
...  
Keyword(s):  
Eye Movement ◽  
Smooth Pursuit ◽  
Clinical Risk ◽  
Smooth Pursuit Eye Movement ◽  
Eye Movement Dysfunction

Role of primate cerebellar lobulus petrosus of paraflocculus in smooth pursuit eye movement control revealed by chemical lesion

2008 ◽  
Vol 60 (3) ◽  
pp. 250-258 ◽  
Author(s):  
Takahito Hiramatsu ◽  
Masafumi Ohki ◽  
Hiromasa Kitazawa ◽  
Guoxiang Xiong ◽  
Taiko Kitamura ◽  
...  
Keyword(s):  
Eye Movement ◽  
Smooth Pursuit ◽  
Movement Control ◽  
Eye Movement Control ◽  
Smooth Pursuit Eye Movement ◽  
Chemical Lesion

scholarly journals Role of Central and Peripheral Retinal Lesions on Optokinetic Nystagmus and Smooth Pursuit Eye Movement.

1991 ◽  
Vol 50 (4) ◽  
pp. 423-428
Author(s):  
Sadao Ogino ◽  
Isao Kato ◽  
Syoji Watanabe ◽  
Kaoruko Takahashi ◽  
Isamu Takeyama
Keyword(s):  
Eye Movement ◽  
Smooth Pursuit ◽  
Optokinetic Nystagmus ◽  
Retinal Lesions ◽  
Smooth Pursuit Eye Movement

Smooth-pursuit eye movement dysfunction and liability for schizophrenia: Implications for genetic modeling.

1992 ◽  
Vol 101 (1) ◽  
pp. 117-129 ◽  
Author(s):  
Brett A. Clementz ◽  
William M. Grove ◽  
William G. Iacono ◽  
John A. Sweeney
Keyword(s):  
Eye Movement ◽  
Smooth Pursuit ◽  
Genetic Modeling ◽  
Smooth Pursuit Eye Movement ◽  
Eye Movement Dysfunction

Role of anticipation and prediction in smooth pursuit eye movement control in Parkinson's disease

2012 ◽  
Vol 27 (8) ◽  
pp. 1012-1018 ◽  
Author(s):  
Christoph Helmchen ◽  
Jonas Pohlmann ◽  
Peter Trillenberg ◽  
Rebekka Lencer ◽  
Julia Graf ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Eye Movement ◽  
Smooth Pursuit ◽  
Movement Control ◽  
Eye Movement Control ◽  
Smooth Pursuit Eye Movement

Eye Movement Dysfunction as a Biological Marker of Risk for Schizophrenia

2000 ◽  
Vol 34 (1_suppl) ◽  
pp. A91-A100 ◽  
Author(s):  
Kwang-Hyuk Lee ◽  
Leanne M. Williams
Keyword(s):  
High Risk ◽  
Eye Movement ◽  
Smooth Pursuit ◽  
Biological Marker ◽  
Carrier Status ◽  
Symptom Profiles ◽  
Smooth Pursuit Eye Movement ◽  
Trait Marker ◽  
Eye Movement Dysfunction ◽  
Marker Status

Objective Our aim was to review smooth pursuit eye movement (SPEM) studies in schizophrenia and groups at high risk for schizophrenia, with a view to evaluating the utility of SPEM dysfunction as a biological marker of risk for schizophrenia. Method Smooth pursuit eye movement studies, related saccade function and the unresolved issues in this area of schizophrenia research were addressed. The different perspectives on the trait marker status of SPEM dysfunction, provided by both high-risk studies and related developmental research were considered. Attention was also given to the relationship between eye movement dysfunction and symptom profiles. Results Converging evidence points to the robust and specific nature of SPEM dysfunction in schizophrenia, and highlights the role of frontal lobe and a related network dysfunction. The vast majority of ‘high risk’ studies support the view that SPEM dysfunction is also genetically specific to schizophrenia, and is not simply due to the overt expression of this illness. Studies assessing SPEM in relation to symptomatology show an association with the Disorganisation syndrome in particular. Conclusions Evidence for the specificity of SPEM dysfunction to diagnosed schizophrenia, as well as to healthy individuals with a genetic vulnerability to schizophrenia, suggests that the SPEM task has efficacy as a test of gene carrier status in schizophrenia, and therefore as a trait marker of risk for schizophrenia. Future studies should seek to explore the relationships between SPEM and other eye movement dysfunctions (antisaccades, express saccades), in view of evidence that some of these dysfunctions also show specificity for schizophrenia.

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