Role of anticipation and prediction in smooth pursuit eye movement control in Parkinson's disease

2012 ◽  
Vol 27 (8) ◽  
pp. 1012-1018 ◽  
Author(s):  
Christoph Helmchen ◽  
Jonas Pohlmann ◽  
Peter Trillenberg ◽  
Rebekka Lencer ◽  
Julia Graf ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Eye Movement ◽  
Smooth Pursuit ◽  
Movement Control ◽  
Eye Movement Control ◽  
Smooth Pursuit Eye Movement

Role of primate cerebellar lobulus petrosus of paraflocculus in smooth pursuit eye movement control revealed by chemical lesion

2008 ◽  
Vol 60 (3) ◽  
pp. 250-258 ◽  
Author(s):  
Takahito Hiramatsu ◽  
Masafumi Ohki ◽  
Hiromasa Kitazawa ◽  
Guoxiang Xiong ◽  
Taiko Kitamura ◽  
...  
Keyword(s):  
Eye Movement ◽  
Smooth Pursuit ◽  
Movement Control ◽  
Eye Movement Control ◽  
Smooth Pursuit Eye Movement ◽  
Chemical Lesion

scholarly journals Role of Primate Cerebellar Hemisphere in Voluntary Eye Movement Control Revealed by Lesion Effects

2009 ◽  
Vol 101 (2) ◽  
pp. 934-947 ◽  
Author(s):  
Masafumi Ohki ◽  
Hiromasa Kitazawa ◽  
Takahito Hiramatsu ◽  
Kimitake Kaga ◽  
Taiko Kitamura ◽  
...  
Keyword(s):  
Eye Movements ◽  
Eye Movement ◽  
Smooth Pursuit ◽  
Movement Control ◽  
Cerebellar Hemisphere ◽  
Target Velocity ◽  
Eye Movement Control ◽  
Pursuit Eye Movements ◽  
Catch Up

The anatomical connection between the frontal eye field and the cerebellar hemispheric lobule VII (H-VII) suggests a potential role of the hemisphere in voluntary eye movement control. To reveal the involvement of the hemisphere in smooth pursuit and saccade control, we made a unilateral lesion around H-VII and examined its effects in three Macaca fuscata that were trained to pursue visually a small target. To the step (3°)-ramp (5–20°/s) target motion, the monkeys usually showed an initial pursuit eye movement at a latency of 80–140 ms and a small catch-up saccade at 140–220 ms that was followed by a postsaccadic pursuit eye movement that roughly matched the ramp target velocity. After unilateral cerebellar hemispheric lesioning, the initial pursuit eye movements were impaired, and the velocities of the postsaccadic pursuit eye movements decreased. The onsets of 5° visually guided saccades to the stationary target were delayed, and their amplitudes showed a tendency of increased trial-to-trial variability but never became hypo- or hypermetric. Similar tendencies were observed in the onsets and amplitudes of catch-up saccades. The adaptation of open-loop smooth pursuit velocity, tested by a step increase in target velocity for a brief period, was impaired. These lesion effects were recognized in all directions, particularly in the ipsiversive direction. A recovery was observed at 4 wk postlesion for some of these lesion effects. These results suggest that the cerebellar hemispheric region around lobule VII is involved in the control of smooth pursuit and saccadic eye movements.

Deficits in saccadic eye-movement control in Parkinson's disease

2005 ◽  
Vol 43 (5) ◽  
pp. 784-796 ◽  
Author(s):  
Florence Chan ◽  
Irene T. Armstrong ◽  
Giovanna Pari ◽  
Richard J. Riopelle ◽  
Douglas P. Munoz
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Eye Movement ◽  
Movement Control ◽  
Saccadic Eye Movement ◽  
Eye Movement Control
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