Anti-IgE-induced histamine release from rat tissues passively sensitizedin vivo with myeloma IgE differs with strain and mast cell source

1984 ◽  
Vol 14 (2) ◽  
pp. 157-165 ◽  
Author(s):  
Håkan Bergstrand ◽  
Anette Björnsson ◽  
Inga Maria Frick ◽  
Britta Lundquist ◽  
Romain Pauwels ◽  
...  
Keyword(s):  
Mast Cell ◽  
Histamine Release ◽  
Rat Tissues ◽  
Cell Source

Histamine release and mast cell degranulation induced by 2-4 dinitrophenol in rat tissues

1969 ◽  
Vol 25 (3) ◽  
pp. 244-245 ◽  
Author(s):  
Mercedes P. de Oliveira Antonio ◽  
A. M. Rothschild
Keyword(s):  
Mast Cell ◽  
Histamine Release ◽  
Mast Cell Degranulation ◽  
Rat Tissues

scholarly journals Histamine-releasing factor/translationally controlled tumor protein (HRF/TCTP)-induced histamine release is enhanced with SHIP-1 knockdown in cultured human mast cell and basophil models

2008 ◽  
Vol 84 (4) ◽  
pp. 1151-1158 ◽  
Author(s):  
Jacqueline M. Langdon ◽  
John T. Schroeder ◽  
Becky M. Vonakis ◽  
Anja P. Bieneman ◽  
Kristin Chichester ◽  
...  
Keyword(s):  
Mast Cell ◽  
Histamine Release ◽  
Human Mast Cell ◽  
Translationally Controlled Tumor Protein

Local histamine release after immunological and non-immunological mast cell degranulationin vivo

1984 ◽  
Vol 14 (3-4) ◽  
pp. 417-419 ◽  
Author(s):  
P. W. Ind ◽  
A. Miyatake ◽  
D. J. Heavey ◽  
C. T. Dollery
Keyword(s):  
Mast Cell ◽  
Histamine Release

Mast cell tumor histamine release following morphine exposure both in vitro and in vivo

2018 ◽  
Vol 45 (6) ◽  
pp. 885.e4
Author(s):  
Taylor Curley ◽  
Pedro Boscan ◽  
Douglas Thamm ◽  
Sam Johnson
Keyword(s):  
Mast Cell ◽  
Histamine Release ◽  
Cell Tumor ◽  
Mast Cell Tumor

Inhibition of Rat Mast Cell Degranulation and Histamine Release by Histamine-Rat Gammaglobulin Conjugate

1979 ◽  
Vol 59 (4) ◽  
pp. 403-407 ◽  
Author(s):  
Takeru Ishikawa ◽  
Tetsuo Shimada ◽  
Nobuko Kessoku ◽  
Masayoshi Kiyoi
Keyword(s):  
Mast Cell ◽  
Histamine Release ◽  
Mast Cell Degranulation

Immunologic mast cell-mediated responses and histamine release are attenuated by heparin

1992 ◽  
Vol 73 (3) ◽  
pp. 1093-1101 ◽  
Author(s):  
J. Lucio ◽  
J. D'Brot ◽  
C. B. Guo ◽  
W. M. Abraham ◽  
L. M. Lichtenstein ◽  
...  
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Histamine Release ◽  
Immunoglobulin E ◽  
Specific Antigen ◽  
Calcium Ionophore ◽  
Intradermal Injection ◽  
Calcium Ionophore A23187 ◽  
Ionophore A23187 ◽  
Dependent Manner

Heparin has been shown to act as a competitive inhibitor of inositol 1,4,5-triphosphate (InsP3) receptors in various cell types. Because InsP3 is one of the second messengers involved in stimulus-secretion coupling in mast cells, it is possible that heparin may inhibit mast cell-mediated reactions. Therefore, in allergic sheep, we tested this hypothesis in two mast cell-mediated reactions induced by immunologic and nonimmunologic stimuli: immediate cutaneous reaction (ICR) and acute bronchoconstrictor response (ABR). In 12 sheep allergic to Ascaris suum antigen, the surface area of the skin wheal was determined 20 min after intradermal injection (0.05 ml) of increasing concentrations of specific antigen, compound 48/80, and histamine, without and after pretreatment with heparin (100, 300, or 1,000 U/kg i.v.). Antigen, compound 48/80, and histamine produced concentration-dependent increases in ICR. Heparin “partially” inhibited the ICR to antigen and compound 48/80 in a dose-dependent manner without modifying the ICR to histamine. The heparin preservative benzyl alcohol was ineffective. In 11 additional sheep, specific lung resistance was measured before and after inhalation challenges with antigen, compound 48/80, and histamine without and with aerosol heparin pretreatment (1,000 U/kg). Heparin blocked the antigen- and compound 48/80-induced bronchoconstriction without modifying the airway effects of histamine. In isolated human uterine mast cells, heparin inhibited the anti-immunoglobulin E- but not the calcium ionophore- (A23187) induced histamine release. These data suggest that heparin inhibits the ICR and ABR induced by stimuli that produce immunologic and nonimmunologic mast cell degranulation without attenuating the effects of histamine.(ABSTRACT TRUNCATED AT 250 WORDS)

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