Squamous-cell carcinoma arising in a non-irradiated child with recurrent respiratory papillomatosis

1993 ◽  
Vol 152 (9) ◽  
pp. 776-778 ◽  
Author(s):  
B. Simma ◽  
R. Burger ◽  
J. Uehlinger ◽  
D. Ghelfi ◽  
E. Hof ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Recurrent Respiratory Papillomatosis

Recurrent respiratory papillomatosis progressing into squamous cell carcinoma in an HIV-positive patient

Apmis ◽  
2015 ◽  
Vol 123 (9) ◽  
pp. 821-822 ◽  
Author(s):  
Michael Barsky ◽  
Hassan S. Moghaddas ◽  
Sarah Almubarak ◽  
Craig M. Forleiter ◽  
Adnan M. Al-Ayoubi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Recurrent Respiratory Papillomatosis ◽  
Positive Patient ◽  
Hiv Positive

scholarly journals A case of primary tracheal squamous cell carcinoma arising from malignant transformation of recurrent respiratory papillomatosis, with a complete response to concurrent chemoradiotherapy

2021 ◽  
Vol 9 ◽  
pp. 2050313X2110546
Author(s):  
Aaron C Kovacs ◽  
Domagoj Vodanovich ◽  
Emily K Mogridge ◽  
Lisa Wun ◽  
June Corry
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Squamous Cell ◽  
Metabolic Response ◽  
Therapeutic Option ◽  
Treatment Options ◽  
Complete Response ◽  
Recurrent Respiratory Papillomatosis ◽  
Positron Emission

Recurrent respiratory papillomatosis is a human papillomavirus-mediated condition characterised by the development of benign squamous papillomata of the respiratory tract. Malignant transformation of recurrent respiratory papillomatosis, while rare, carries a poor prognosis and there are limited data surrounding treatment options, particularly in inoperable disease. We present the case of a 64-year-old male who developed malignant airway obstruction secondary to primary tracheal squamous cell carcinoma in the setting of a 5-year history of recurrent laryngotracheal papillomatosis, requiring placement of tracheostomy while on veno-venous extracorporeal membranous oxygenation. He was managed with cisplatin-based definitive chemoradiotherapy and had a complete metabolic response on post-treatment positron emission tomography/computed tomography, and remains free of recurrent squamous cell carcinoma at 16 months following treatment. This case supports the use of combined chemoradiotherapy as a potential therapeutic option for patients with primary tracheal squamous cell carcinoma, and emphasises the challenges associated with the long-term management of recurrent respiratory papillomatosis.

Human Papillomavirus Vaccination Counseling in Pediatric Training

2016 ◽  
Vol 155 (1) ◽  
pp. 87-93 ◽  
Author(s):  
Sharon H. Gnagi ◽  
Forrest T. Gnagi ◽  
Scott A. Schraff ◽  
Michael L. Hinni
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Online Survey ◽  
Hpv Vaccination ◽  
Tertiary Care ◽  
Recurrent Respiratory Papillomatosis ◽  
Oropharyngeal Squamous Cell Carcinoma ◽  
Human Papillomavirus Vaccination

Objective Demonstrate the need for increased education regarding otolaryngology-related manifestations of human papillomavirus (HPV). Highlight a need to incorporate otolaryngology-related manifestations of HPV in vaccine counseling. Study Design Survey. Setting Tertiary care academic children’s hospital. Subjects Pediatric residents, fellows, and staff. Methods An online survey was made available regarding HPV education and vaccination. Results Participants (N = 348) initiated the survey representing 28.4%, 25.6%, and 19.0% postgraduate year 1, 2, and 3 residents, respectively, as well as 17.5% chief residents/fellows and 9.5% attendings. Participants rated their prior education as none or fair regarding recurrent respiratory papillomatosis (63.8%) and oropharyngeal squamous cell carcinoma (68.3%). In contrast, 60.6% and 70.9% rated their education on genital warts and cervical cancer correspondingly as good or excellent. When asked what was routinely discussed during HPV vaccine counseling, 63.3% reported “never” discussing recurrent respiratory papillomatosis and 52.9% “never” discussing oropharyngeal squamous cell carcinoma. A range from 92.7% to 95.5% responded that there was a need for increased education regarding HPV and its role in recurrent respiratory papillomatosis and oropharyngeal squamous cell carcinoma. Conclusions Increased education about HPV and its otolaryngology-related manifestations should be undertaken to increase provider, patient, and parent awareness of recurrent respiratory papillomatosis and oropharyngeal squamous cell carcinoma. We propose that discussing the risks of otolaryngology-related disease be routinely included in HPV vaccination counseling.

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