Dietary carbohydrate and tissue cholesterol concentration in young rats

1970 ◽  
Vol 26 (1) ◽  
pp. 57-58 ◽  
Author(s):  
R. A. Ahrens ◽  
T. V. Besser ◽  
E. M. Blyler ◽  
J. M. Daniel ◽  
J. W. Smith
Keyword(s):  
Cholesterol Concentration ◽  
Dietary Carbohydrate ◽  
Young Rats ◽  
Tissue Cholesterol

Studies on the Etiology of Increased Tissue Cholesterol Concentration in Cholesterol-Fed Hypothyroid Rats

1982 ◽  
Vol 112 (12) ◽  
pp. 2324-2332 ◽  
Author(s):  
P. M. Kris-Etherton ◽  
Mary Ann Fosmire ◽  
D. J. Mela ◽  
Terry D. Etherton
Keyword(s):  
Cholesterol Concentration ◽  
Tissue Cholesterol

THE EFFECT OF COLD EXPOSURE ON PLASMA AND LIVER CHOLESTEROL LEVELS IN RATS FED VARIOUS DIETS

1964 ◽  
Vol 42 (6) ◽  
pp. 779-785
Author(s):  
J. D. Wood
Keyword(s):  
Cold Exposure ◽  
Small Difference ◽  
Cholesterol Concentration ◽  
Liver Cholesterol ◽  
Deficient Diet ◽  
Cholesterol Levels ◽  
Male Wistar Rats ◽  
Fatty Livers ◽  
Tissue Cholesterol ◽  
Environmental Temperatures

Plasma and liver cholesterol levels were compared in male Wistar rats kept at environmental temperatures of 2 °C and 23 °C on various dietary regimens. Cold exposure had little or no effect on the tissue cholesterol levels provided the diet contained appreciable amounts of choline and inositol, the only statistically significant change observed being a small difference in the liver cholesterol concentration in rats maintained on a cholesterol-free diet. A choline- and inositol-deficient diet produced a hypocholesterolemic effect in rats at 23 °C but this effect was counteracted by exposing the rats to a cold environment. The possible significance of this observation with regard to the biochemical defect in "choline deficient" fatty livers is discussed.

On the Fibrinolytic System in Aged Rats, and Its Reactivity to Endotoxin and Cytokines

1992 ◽  
Vol 67 (06) ◽  
pp. 697-701 ◽  
Author(s):  
J J Emeis ◽  
A Brouwer ◽  
R J Barelds ◽  
M A Horan ◽  
S K Durham ◽  
...  
Keyword(s):  
Plasminogen Activator ◽  
Fibrinolytic Activity ◽  
Fibrinolytic System ◽  
Tissue Type ◽  
High Dose ◽  
Base Line ◽  
Aged Rats ◽  
Tissue Type Plasminogen Activator ◽  
Young Rats ◽  
Type Plasminogen Activator

SummaryAged rats are more susceptible to endotoxin-induced effects, including microthrombosis and platelet aggregation, than are young rats. To investigate whether changes in the fibrinolytic system might be involved, we investigated the fibrinolytic activity in plasma euglobulin fractions and tissues (lung and heart) of young (6-months old) and aged (24-months old) rats under baseline conditions and after challenge with endotoxin. Aged rats had lower plasma levels of tissue-type plasminogen activator (t-PA) and of urokinase-type PA (u-PA) activity. PA inhibitor (PAI) activity was higher in the plasma of aged rats, as was t-PA activity in lung and heart.Rats were treated with either a low dose (1 μg/kg) or a high dose (10 mg/kg) of endotoxin. Both treatments induced a transient phase of increased blood fibrinolytic activity, as evidenced by higher levels of tissue-type plasminogen activator (t-PA) activity and decreased levels of PA inhibitor (PAI) activity. Over time, the fibrinolytic activity decreased, probably due to increased levels of PA inhibitor.Both the early increase in t-PA activity, and the subsequent increase in PAI activity, were more pronounced in the aged rats, as compared with the younger rats, after the high dose of endotoxin. The aged rats also responded to an injection of interleukin-1β or tumor necrosis factor-α with a larger increase of PAI activity than did the younger rats.Together the data suggest that, compared to young rats, aged rats have a decreased base-line plasma fibrinolytic activity, while their fibrinolytic system is more responsive to challenge by endotoxin and cytokines.

Platelet Aggregation and Plasma Lipoproteins in Alcoholics During Alcohol Withdrawal

1986 ◽  
Vol 55 (02) ◽  
pp. 173-177 ◽  
Author(s):  
K Desai ◽  
J S Owen ◽  
D T Wilson ◽  
R A Hutton
Keyword(s):  
Platelet Aggregation ◽  
Alcohol Withdrawal ◽  
Ldl Cholesterol ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Plasma Lipoprotein ◽  
Cholesterol Concentration ◽  
Arachidonic Acid Content ◽  
Low Density

SummaryPlatelet aggregation, platelet lipid composition and plasma lipoprotein concentrations were measured each week in a group of seventeen alcoholics, without overt liver disease, for one month, following acute, total alcohol withdrawal. The platelets were initially hypoaggregable but, within 1-2 weeks of cessation of drinking, they became hyperaggregable and then gradually returned towards normal values. Hyperaggregability could not be explained by increases in either the cholesterol or the arachidonic acid content of the platelets. Plasma very-low-density lipoprotein cholesterol levels remained high throughout the study, but the initially raised levels of high-density lipoprotein (HDL) cholesterol fell by 26%. Low-density lipoprotein (LDL) cholesterol concentration rose by 10% after two weeks of withdrawal but then returned to about the starting level. The resulting changes in the plasma LDL-cholesterol: HDL-cholesterol ratio, which had increased by more than 50% after two weeks of abstinence, essentially paralleled the time course of enhanced platelet reactivity in all but four of the alcoholics. These findings suggest that alterations in plasma lipoprotein concentrations during acute alcohol withdrawal may be a contributory factor to the haemostatic disorders present in such patients.

CLINICAL INVESTIGATIONS OF A LONG-ACTING OESTRIOL (POLYOESTRIOL PHOSPHATE)

1961 ◽  
Vol 38 (1) ◽  
pp. 73-87 ◽  
Author(s):  
Christian Lauritzen ◽  
Semih Velibese
Keyword(s):  
Side Effects ◽  
Phosphoric Acid ◽  
Quantitative Data ◽  
Water Soluble ◽  
Cholesterol Concentration ◽  
Experimental Investigations ◽  
Clinical Investigations ◽  
Prolonged Duration ◽  
High Doses ◽  
Long Acting

ABSTRACT A description is given of experimental investigations and preliminary clinical experience with the long-acting oestriol compound polyoestriol phosphate – a water-soluble polymere of oestriol and phosphoric acid. The compound seems to exert all the physiologically important effects of oestriol. Even with high doses the hormone causes no proliferation of the endometrium and no withdrawal bleeding. It has no untoward effect on metabolism. It decreases slightly the cholesterol concentration (to the extent of ⅓–⅕ of the effect produced by long-acting oestradiol esters). The compound has a wide therapeutic range. No side-effects have been observed. Doses of 10 mg or more have a prolonged duration. Additional prolongation of the effect is largely dependent on dosage. To ensure an effect lasting for 4 weeks 40 mg polyoestriol phosphate (corresponding with 30 mg oestriol) is required – an amount which roughly corresponds with physiological quantitative data. The compound, which involves an interesting new principle of prolongation, was most effectively used in the treatment of menopausal symptoms and genital organic disorders. For these indications it can be recommended without reservation.

EFFICACY OF SALICYLIC AND ASCORBIC ACIDS TO REDUCE THE EFFECT OF TRANSPORT STRESS ON LIVE WEIGHT, SOME BLOOD CHARACTERISTICS AND INTESTINAL VILLI OF BROILER CHICKENS

2020 ◽  
Vol 51 (4) ◽  
pp. 1074-1081
Author(s):  
Al obaydy & et al.
Keyword(s):  
Ascorbic Acid ◽  
Drinking Water ◽  
Transport Process ◽  
Live Weight ◽  
Cholesterol Concentration ◽  
Control Treatment ◽  
Intestinal Villi ◽  
Slaughter House ◽  
Transport Stress ◽  
Financial Losses

This experiment was conducted and aimed to reducing mortality and losing the weight of birds transported to the slaughter house through reducing or Transport stress removal and thus to reduce financial losses. 150 birds used almost equal weights that were divided into three treatment groups and by five replicates for each treatment is control treatment (T1) without giving anything and treatment with salicylic acid concentration 1 g / liter of drinking water (T2) and treatment with ascorbic acid (T3) concentration 0.5 g / Liter of drinking water provided 24 hours before its transport. The transport process resulted in a highly significant decrease (P ≤ 0.01) in body weight in treatment T1 as it reached 4.66%, while it reached 1.68 and 1.09% in treatment T2 and T3, respectively. The transport process led to an increase in body temperature, H / L ratio, the concentration of glucose, aspartate transaminase (AST) and alanine transaminase (ALT) in the blood serum, as the transport process led to a very significant decrease (P ≤ 0.01) in the cholesterol concentration, Uric acid, intestinal villi length and crypts depth. T2 and T3 treatments showed their ability to reduce transport stress, especially T3, where they outperformed T1 in most traits. It is concluded from the study that adding ascorbic acid by 0.5 g / L drinking water 24 hours before transporting the chicks to the slaughter house reduces the transport stress and lessen financial losses, so it is recommended to use it.

INFLUENCE OF DIETARY CARBOHYDRATE LEVELS ON GROWTH AND SOME PHYSIOLOGICAL-BIOCHEMICAL INDEX IN JUVENILE LITOPENAEUS VANNAMEI

2009 ◽  
Vol 33 (2) ◽  
pp. 289-295 ◽  
Author(s):  
Yi HU ◽  
Bei-Ping TAN ◽  
Kang-Sen MAI ◽  
Qing-Hui AI ◽  
Shi-Xuan ZHENG ◽  
...  
Keyword(s):  
Litopenaeus Vannamei ◽  
Dietary Carbohydrate ◽  
Biochemical Index ◽  
Carbohydrate Levels

Effect of KH-305 on the Nitric Oxide Synthase Activity and Erectile Dysfunction in Young Rats

2007 ◽  
Vol 36 (3) ◽  
pp. 305-310 ◽  
Author(s):  
Eun-Jeong Lee ◽  
Hee-Seok Kim ◽  
Byoung-Chul Kim ◽  
Sung-Wan Hwang ◽  
Sung-Yeoun Hwang
Keyword(s):  
Nitric Oxide ◽  
Erectile Dysfunction ◽  
Nitric Oxide Synthase ◽  
Young Rats ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity
Sign in / Sign up

Export Citation Format

Share Document