Acute toxic responses of the freshwater planarian,Dugesia dorotocephala, to chlordane

1981 ◽  
Vol 26 (1) ◽  
pp. 502-507 ◽  
Author(s):  
Jay Boyd Best ◽  
Michio Morita ◽  
Bruce Abbotts
Keyword(s):  
Freshwater Planarian ◽  
Dugesia Dorotocephala ◽  
Toxic Responses ◽  
Acute Toxic

Histopathology of Acute Toxic Responses in Selected Tissues from Rats Exposed by Inhalation to Methyl Bromide

1987 ◽  
Vol 9 (2) ◽  
pp. 352-365
Author(s):  
MARK E. HURTT ◽  
KEVIN T. MORGAN ◽  
PETER K. WORKING
Keyword(s):  
Methyl Bromide ◽  
Toxic Responses ◽  
Acute Toxic

Acute toxic responses of embryo-larval zebrafish to zinc pyrithione (ZPT) reveal embryological and developmental toxicity

Chemosphere ◽  
2018 ◽  
Vol 205 ◽  
pp. 62-70 ◽  
Author(s):  
Ye Zhao ◽  
Yuyang Liu ◽  
Jing Sun ◽  
Hongtao Sha ◽  
Yu Yang ◽  
...  
Keyword(s):  
Developmental Toxicity ◽  
Zinc Pyrithione ◽  
Larval Zebrafish ◽  
Toxic Responses ◽  
Acute Toxic

Effect of Seasonal Photoperiod on Acute Toxic Responses of Juvenile Rainbow Trout (Salmo gairdneri) to Pulpmill Effluent

1978 ◽  
Vol 35 (10) ◽  
pp. 1388-1392 ◽  
Author(s):  
Donald J. McLeay ◽  
Michael R. Gordon
Keyword(s):  
Rainbow Trout ◽  
Blood Sugar ◽  
Threshold Effect ◽  
Tolerance Test ◽  
Temperature Tolerance ◽  
Toxicity Tests ◽  
Salmo Gairdneri ◽  
Jar Test ◽  
Toxic Responses ◽  
Acute Toxic

Acute toxic responses to bleached kraft pulpmill effluent were compared for groups of underyearling rainbow trout (Salmo gairdneri) reared under constant temperature and either a summer (16L:8D) or winter (8L:16D) photoperiod. Toxicity tests included a 96-h LC50 bioassay, a 4.5-h sealed-jar test, an 18-h temperature tolerance test, and a 4-h blood-sugar stress bioassay. For all tests the threshold-effect concentration of effluent was not affected by photoperiod. Median effective concentrations for the blood-sugar, temperature tolerance, and sealed-jar tests were, respectively, < 0.2, 0.4, and ~1.4 times the 96-h LC50 value for each fish group. Key words: Salmo gairdneri, photoperiod, BKME, acute toxicity tests, LC50, blood sugar, temperature tolerance, residual oxygen

The AH Receptor and a Novel Gene Determine Acute Toxic Responses to TCDD: Segregation of the Resistant Alleles to Different Rat Lines

1999 ◽  
Vol 155 (1) ◽  
pp. 71-81 ◽  
Author(s):  
Jouni T. Tuomisto ◽  
Matti Viluksela ◽  
Raimo Pohjanvirta ◽  
Jouko Tuomisto
Keyword(s):  
Ah Receptor ◽  
Novel Gene ◽  
Toxic Responses ◽  
Acute Toxic

Acetaminophen: Macula densa hypersecretory activity by induced hepatotoxicity

1987 ◽  
Vol 45 ◽  
pp. 934-935
Author(s):  
S.S. Poolsawat ◽  
C.A. Huerta ◽  
S.TY. Lae ◽  
G.A. Miranda
Keyword(s):  
Cell Proliferation ◽  
Liver Function ◽  
Chronic Inflammation ◽  
Foam Cell ◽  
Term Effect ◽  
Short Term ◽  
Drug Induced ◽  
Experimental Induction ◽  
Tissue Alterations ◽  
Toxic Responses

Introduction. Experimental induction of altered histology by chemical toxins is of particular importance if its outcome resembles histopathological phenomena. Hepatotoxic drugs and chemicals are agents that can be converted by the liver into various metabolites which consequently evoke toxic responses. Very often, these drugs are intentionally administered to resolve an illness unrelated to liver function. Because of hepatic detoxification, the resulting metabolites are suggested to be integrated into the macromolecular processes of liver function and cause an array of cellular and tissue alterations, such as increased cytoplasmic lysis, centrilobular and localized necroses, chronic inflammation and “foam cell” proliferation of the hepatic sinusoids (1-4).Most experimentally drug-induced toxicity studies have concentrated primarily on the hepatic response, frequently overlooking other physiological phenomena which are directly related to liver function. Categorically, many studies have been short-term effect investigations which seldom have followed up the complications to other tissues and organs when the liver has failed to function normally.

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