Prognostic implications of DNA ploidy in squamous cell carcinomas of the tongue assessed by flow cytometry

1990 ◽  
Vol 116 (1) ◽  
pp. 83-86 ◽  
Author(s):  
J. Hemmer ◽  
E. Schön ◽  
J. Kreidler ◽  
S. Haase
Keyword(s):  
Flow Cytometry ◽  
Squamous Cell ◽  
Dna Ploidy ◽  
Squamous Cell Carcinomas ◽  
Prognostic Implications

DNA Ploidy, Proliferation Index, Grade, and Stage as Prognostic Factors for Vulvar Squamous Cell Carcinomas

1993 ◽  
Vol 48 (2) ◽  
pp. 232-235 ◽  
Author(s):  
James R. Dolan ◽  
Anne R. McCall ◽  
Saro Gooneratne ◽  
Scott Walter ◽  
David M. Lansky
Keyword(s):  
Prognostic Factors ◽  
Squamous Cell ◽  
Dna Ploidy ◽  
Squamous Cell Carcinomas ◽  
Proliferation Index

Prognostic significance of DNA ploidy in oral squamous cell carcinomas

1995 ◽  
Vol 79 (1) ◽  
pp. 68-76 ◽  
Author(s):  
G. Baretton ◽  
Xun Li ◽  
C. Stoll ◽  
E. Fischer-Brandies ◽  
M. Schmidt ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Dna Ploidy ◽  
Prognostic Significance ◽  
Squamous Cell Carcinomas ◽  
Oral Squamous Cell Carcinomas

scholarly journals Chromosomal Composition of Aneuploid Clones with Different DNA Contents in Head and Neck Squamous Cell Carcinomas as Determined by Combined Flow Cytometry and FluorescenceIn SituHybridization

2000 ◽  
Vol 20 (4) ◽  
pp. 197-203 ◽  
Author(s):  
Joerg Hemmer ◽  
Carmen Hauser
Keyword(s):  
Flow Cytometry ◽  
Head And Neck ◽  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Dna Probes ◽  
Chromosome 17 ◽  
Cell Populations ◽  
Dna Flow Cytometry ◽  
Wide Range ◽  
Dna Contents

Studies with DNA flow cytometry (FCM) have shown that DNA contents of aneuploid tumour clones vary in a wide range. The aim of this study was to analyse whether homologous chromosomal changes exist despite the individual differences that may be of general relevance for the development of gross aneuploidy in squamous cell carcinomas of the head and neck. Fluorescencein situhybridization (FISH) with 13 centromere‐specific DNA probes was applied to 3 diploid and 11 aneuploid tumours with DNA indices ranging between 0.8 and 2.2. Disomic and monosomic cell populations were prevalent findings in DNA‐diploid tumours. Polysomies were common in aneuploid tumours. Different degrees of aneusomy for identical chromosomes were recurrent features in aneuploid tumours. FISH signal heterogeneity was identified for all chromosomes. The mean number of aneusomic cell populations identified for DNA‐aneuploid tumours ranged between 1.6 for chromosome 17 and 3.1 for chromosome 3. Inconsistencies between FISH and FCM data may indicate that centromere‐specific DNA probes identify gains and losses of marker DNA due to complex karyotypic rearrangements rather than absolute changes in chromosome numbers. Overall, there was no evidence of the critical involvement of particular chromosomes in the development of different DNA contents.

scholarly journals Influence of preoperative radiotherapy on DNA ploidy in squamous cell carcinomas of the oesophagus.

Gut ◽  
1993 ◽  
Vol 34 (8) ◽  
pp. 1086-1090 ◽  
Author(s):  
R Porschen ◽  
G Bevers ◽  
U Remy ◽  
S Schauseil ◽  
F Borchard
Keyword(s):  
Squamous Cell ◽  
Preoperative Radiotherapy ◽  
Dna Ploidy ◽  
Squamous Cell Carcinomas

Core classification of head and neck squamous cell carcinomas: Correlations between morphology, DNA ploidy and HPV infection

2010 ◽  
Vol 206 (11) ◽  
pp. 768-771 ◽  
Author(s):  
Waleed F.M. Amin Kotb ◽  
Christiane Blind ◽  
Karl-Heinz Friedrich ◽  
Christiane Schewe ◽  
Zhi Gang Zhang ◽  
...  
Keyword(s):  
Head And Neck ◽  
Squamous Cell ◽  
Dna Ploidy ◽  
Hpv Infection ◽  
Squamous Cell Carcinomas ◽  
Core Classification
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