Circadian rhythmicity in the methylation of 5-hydroxy-indoles and norepinephrine in the pineal gland of 10 day old rats

1978 ◽  
Vol 43 (2) ◽  
pp. 167-175 ◽  
Author(s):  
M. G. M. Balemans ◽  
F. A. M. Bary ◽  
W. C. Legerstee ◽  
E. M. Noordegraaf
Keyword(s):  
Pineal Gland ◽  
Circadian Rhythmicity ◽  
Old Rats

Gonadal function in male offspring of pinealectomized female rats

1987 ◽  
Vol 116 (2) ◽  
pp. 247-252 ◽  
Author(s):  
J. F. Jarrige ◽  
O. Tlemcani ◽  
D. Boucher
Keyword(s):  
Pineal Gland ◽  
Male Offspring ◽  
Female Rats ◽  
Short Photoperiod ◽  
Plasma Testosterone ◽  
Testicular Function ◽  
Gonadal Function ◽  
Old Rats

Abstract. Female rats were exposed to a short (6 L: 18 D) photoperiod from 21 days of age. On day 2 of gestation, animals were pinealectomized or sham-operated. Lighting regimens were not changed during the course of the study. Male offspring of the 2 groups of rats were sacrificed on days 30, 42 and 49 after birth. Pinealectomy of the mother induced the following modifications: in 30-day-old offsprings, a decrease in prostatic weight and plasma dihydrotestosterone level; in 42-day-old rats, a decrease in prostatic weight, in testicular androstenedione and dihydrotestosterone content, and in plasma testosterone and dihydrotestosterone levels; in 49-day-old animals, decreased testicular and plasma testosterone and dihydrotestosterone levels. These results indicate that rat testicular function, after exposure to a short photoperiod beginning before conception, is decreased by maternal pinealectomy. The mother's pineal gland may play a part in the control of rat testicular function.

scholarly journals The influence of some pterins on the circadian rhythmicity of hydroxyindole-O-methyl transferase in the pineal gland of 42-day old male Wistar rats

1980 ◽  
Vol 20 (4A) ◽  
pp. 1051-1060 ◽  
Author(s):  
M. G. M. BALEMANS ◽  
J. Van BENTHEM ◽  
W. C. LEGERSTEE ◽  
A. de MOREE ◽  
H. J. P. M. NOTEBORN ◽  
...  
Keyword(s):  
Pineal Gland ◽  
Wistar Rats ◽  
Circadian Rhythmicity ◽  
Methyl Transferase ◽  
Male Wistar Rats

scholarly journals Hundreds of LncRNAs Display Circadian Rhythmicity in Zebrafish Larvae

Cells ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 3173
Author(s):  
Shital Kumar Mishra ◽  
Zhaomin Zhong ◽  
Han Wang
Keyword(s):  
Pineal Gland ◽  
3D Structure ◽  
Data Bank ◽  
Circadian Rhythmicity ◽  
Constant Darkness ◽  
Rna Seq ◽  
Functional Studies ◽  
Zebrafish Larvae ◽  
Sequencing Technologies ◽  
Computational Analyses

Long noncoding RNAs (lncRNAs) have been shown to play crucial roles in various life processes, including circadian rhythms. Although next generation sequencing technologies have facilitated faster profiling of lncRNAs, the resulting datasets require sophisticated computational analyses. In particular, the regulatory roles of lncRNAs in circadian clocks are far from being completely understood. In this study, we conducted RNA-seq-based transcriptome analysis of zebrafish larvae under both constant darkness (DD) and constant light (LL) conditions in a circadian manner, employing state-of-the-art computational approaches to identify approximately 3220 lncRNAs from zebrafish larvae, and then uncovered 269 and 309 lncRNAs displaying circadian rhythmicity under DD and LL conditions, respectively, with 30 of them are coexpressed under both DD and LL conditions. Subsequently, GO, COG, and KEGG pathway enrichment analyses of all these circadianly expressed lncRNAs suggested their potential involvement in numerous biological processes. Comparison of these circadianly expressed zebrafish larval lncRNAs, with rhythmically expressed lncRNAs in the zebrafish pineal gland and zebrafish testis, revealed that nine (DD) and twelve (LL) larval lncRNAs are coexpressed in the zebrafish pineal gland and testis, respectively. Intriguingly, among peptides encoded by these coexpressing circadianly expressed lncRNAs, three peptides (DD) and one peptide (LL) were found to have the known domains from the Protein Data Bank. Further, the conservation analysis of these circadianly expressed zebrafish larval lncRNAs with human and mouse genomes uncovered one lncRNA and four lncRNAs shared by all three species under DD and LL conditions, respectively. We also investigated the conserved lncRNA-encoded peptides and found one peptide under DD condition conserved in these three species and computationally predicted its 3D structure and functions. Our study reveals that hundreds of lncRNAs from zebrafish larvae exhibit circadian rhythmicity and should help set the stage for their further functional studies.

Effect of a synthetic pineal tetrapeptide (Ala-Glu-Asp-Gly) on melatonin secretion by the pineal gland of young and old rats

2003 ◽  
Vol 26 (3) ◽  
pp. 211-215 ◽  
Author(s):  
Y. Djeridane ◽  
V. Kh. Khavinson ◽  
V. N. Anisimov ◽  
Yvan Touitou
Keyword(s):  
Pineal Gland ◽  
Melatonin Secretion ◽  
Old Rats
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