The action of acid halides of carboxylic acids on some tertiary amines

1969 ◽  
Vol 18 (4) ◽  
pp. 839-842 ◽  
Author(s):  
Ya. L. Gol'dfarb ◽  
R. M. Ispiryan ◽  
L. I. Belen'kii
Keyword(s):  
Carboxylic Acids ◽  
Tertiary Amines

ChemInform Abstract: Direct Amidation of Carboxylic Acids with Tertiary Amines: Amide Formation over Copper Catalysts Through C-N Bond Cleavage.

ChemInform ◽  
2015 ◽  
Vol 46 (8) ◽  
pp. no-no
Author(s):  
Biquan Xiong ◽  
Longzhi Zhu ◽  
Xiaofeng Feng ◽  
Jian Lei ◽  
Tieqiao Chen ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Bond Cleavage ◽  
Copper Catalysts ◽  
Tertiary Amines ◽  
Amide Formation ◽  
Direct Amidation

Direct Amidation of Carboxylic Acids with Tertiary Amines: Amide Formation over Copper Catalysts through C-N Bond Cleavage

2014 ◽  
Vol 2014 (20) ◽  
pp. 4244-4247 ◽  
Author(s):  
Biquan Xiong ◽  
Longzhi Zhu ◽  
Xiaofeng Feng ◽  
Jian Lei ◽  
Tieqiao Chen ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Bond Cleavage ◽  
Copper Catalysts ◽  
Tertiary Amines ◽  
Amide Formation ◽  
Direct Amidation

Palladium-Catalyzed N-Acylation of Tertiary Amines by Carboxylic Acids: A Method for the Synthesis of Amides

2020 ◽  
Vol 22 (14) ◽  
pp. 5517-5521 ◽  
Author(s):  
Zhaohui Li ◽  
Long Liu ◽  
Kaiqiang Xu ◽  
Tianzeng Huang ◽  
Xinyi Li ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Tertiary Amines ◽  
Palladium Catalyzed

Reactions of the Silver Salts of Carboxylic Acids with Iodine in the Presence of Some Tertiary Amines

1949 ◽  
Vol 71 (2) ◽  
pp. 575-576 ◽  
Author(s):  
Ralph A. Zingaro ◽  
Judson E. Goodrich ◽  
Jacob. Kleinberg ◽  
Calvin A. VanderWerf
Keyword(s):  
Carboxylic Acids ◽  
Tertiary Amines ◽  
Silver Salts

scholarly journals Anti-Markovnikov hydro(amino)alkylation of vinylarenes via photoredox catalysis

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Zhao Wu ◽  
Samuel N. Gockel ◽  
Kami L. Hull
Keyword(s):  
Carboxylic Acids ◽  
Tertiary Amine ◽  
Alkyl Radical ◽  
Tertiary Amines ◽  
Photoredox Catalysis ◽  
Reaction Conditions ◽  
Synthetic Utility ◽  
Powerful Means

AbstractPhotoredox catalysis is a powerful means to generate odd-electron species under mild reaction conditions from a wide array of radical precursors. Herein, we present the application of this powerful catalytic manifold to address the hydroalkylation and hydroaminoalkylation of electronically diverse vinylarenes. This reaction allows for generalized alkene hydroalkylation leveraging common alkyl radical precursors, such as organotrifluoroborate salts and carboxylic acids. Furthermore, utilizing easily accessible α-silyl amine reagents or tertiary amines directly, secondary and tertiary amine moieties can be installed onto monoaryl and diaryl alkenes to access valuable products, including γ,γ-diarylamines pharmacophores. Thus, under a unified system, both hydroalkylation and hydroaminoalkylation of alkenes are achieved. The substrate scope is evaluated through 57 examples, the synthetic utility of the method is demonstrated, and preliminary mechanistic insights are presented.

Detailing the elementary stages in the oxirane ring opening reactions with carboxylic acids catalyzed by tertiary amines

2020 ◽  
Vol 33 (9) ◽  
Author(s):  
Stanislav Bakhtin ◽  
Elena Shved ◽  
Yuliia Bespalko ◽  
Tatyana Tyurina ◽  
Vitalii Palchykov
Keyword(s):  
Carboxylic Acids ◽  
Ring Opening ◽  
Oxirane Ring ◽  
Tertiary Amines ◽  
Ring Opening Reactions

Ynoate-Initiated Selective C–N Esterification of Tertiary Amines under Transition-Metal and Oxidant-Free Conditions

Synlett ◽  
2020 ◽  
Author(s):  
Huangdi Feng ◽  
Junhai Huang ◽  
Feixiang Sun ◽  
Liliang Huang
Keyword(s):  
Transition Metal ◽  
Carboxylic Acids ◽  
Dissociation Energy ◽  
Good Yield ◽  
Tertiary Amines ◽  
Selective Method ◽  
In Situ Generation

AbstractAn efficient and selective method for metal- and oxidant-free deaminated esterification of tertiary amines is presented. In this protocol, ynoates play a key role to activate the Csp3–N bond through a process of in situ generation of zwitterionic salts. The transformations show that Csp3–N bond in the zwitterionic species has a lower dissociation energy than Csp2–N bond, leading to break preferentially and be trapped by carboxylic acids to generate the corresponding products in moderate to good yield.

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