Effect of cholesterol on the state of the adrenal cortex in severe stress

1978 ◽  
Vol 85 (5) ◽  
pp. 569-572 ◽  
Author(s):  
B. Ya. Ryzhavskii ◽  
M. T. Lutsenko
Keyword(s):  
Adrenal Cortex ◽  
The State ◽  
Severe Stress

scholarly journals Observations on epinephrectomized cats treated with adrenal cortex hormone. Hartman F.A., Griffith F.R. Ir and W.I. Hartman (Am. J. of Physiol. 86, 360, 1928)

1929 ◽  
Vol 25 (10) ◽  
pp. 1111-1112
Keyword(s):  
Adrenal Insufficiency ◽  
Adrenal Cortex ◽  
The State ◽  
Daily Injection

The state of chronic adrenal insufficiency was observed in 108 bilaterally epinephrectomized cats with daily injection of an extract from the adrenal cortex. The symptoms were similar to those of acute insufficiency, but in general they tended to develop more gradually.

THE RESPONSE OF THE PITUITARY-ADRENAL SYSTEM TO A STRESSFUL STIMULUS: THE EFFECT OF CONDITIONING AND PENTOBARBITONE TREATMENT

1965 ◽  
Vol 33 (1) ◽  
pp. 145-152 ◽  
Author(s):  
A. M. BARRETT ◽  
M. A. STOCKHAM
Keyword(s):  
Ascorbic Acid ◽  
Adrenal Cortex ◽  
The State ◽  
Adrenal System ◽  
Sites Of Action ◽  
Adrenal Corticosterone ◽  
Stressful Stimulus

SUMMARY Handling of intraperitoneal injections of saline, twice daily for 10 days, did not significantly affect the resting level of corticosterone in the plasma or the adrenals. The conditioning abolished the usual changes in corticosterone levels caused by further handling or injections, reduced the response to exposure to ether vapour and had no effect on the response to histamine. The effect of pentobarbitone on plasma and adrenal corticosterone concentrations was found to be dependent upon the state of the pituitary-adrenal system before administration. Pentobarbitone had no effect on the responses of the adrenal cortex to exogenous adrenocorticotrophin. The responses to ether vapour or histamine of normal rats and rats lightly sedated with pentobarbitone were not significantly different as judged by changes in plasma and adrenal corticosterone concentrations and adrenal ascorbic acid depletion. However, rats deeply anaesthetized with pentobarbitone gave responses indicative of a depression of pituitary-adrenal activity. The sites of action of pentobarbitone on the pituitary-adrenal system are discussed.

The impact of increased physical exertion on the state of adrenal cortex and pubertal development in boys

2014 ◽  
Vol 40 (2) ◽  
pp. 190-196 ◽  
Author(s):  
M. V. Shaykhelislamova ◽  
F. G. Sitdikov ◽  
A. A. Sitdikova ◽  
G. G. Kayumova
Keyword(s):  
Adrenal Cortex ◽  
Pubertal Development ◽  
Physical Exertion ◽  
The State ◽  
The Impact

Child Murder and Insanity

1927 ◽  
Vol 73 (300) ◽  
pp. 95-108 ◽  
Author(s):  
J. Stanley Hopwood
Keyword(s):  
Legal Aspect ◽  
Lunatic Asylum ◽  
The State ◽  
Large Percentage ◽  
Severe Stress ◽  
The Past ◽  
Female Sex ◽  
Child Murder ◽  
Child Bearing

Childbirth and lactation entail a severe stress on the female sex, and, under certain circumstances, are liable to cause insanity, during the course of which attempts at infanticide and suicide are common. For this reason the insanities connected with child-bearing and lactation have a definite medico-legal aspect. In the past very little has been written on this subject, though infanticide is by no means uncommon, and cases of child murder account for a large percentage of the population of the female division of the State Criminal Lunatic Asylum at Broadmoor. Possibly a study of some of these cases may not be lacking in interest.

Ultrastructural Cytopiasmic Changes of Adrenal Cortex During Pregnancy

1969 ◽  
Vol 27 ◽  
pp. 298-299
Author(s):  
T. M. Murad ◽  
Karen Israel ◽  
Jack C. Geer
Keyword(s):  
Adrenal Gland ◽  
Steroid Hormones ◽  
Adrenal Cortex ◽  
Lipid Droplets ◽  
Plasma Cholesterol ◽  
Adrenal Steroids ◽  
Dynamic Changes ◽  
Cortical Cells ◽  
Acetyl Coenzyme A ◽  
Adrenal Cortical Cells

Adrenal steroids are normally synthesized from acetyl coenzyme A via cholesterol. Cholesterol is also shown to enter the adrenal gland and to be localized in the lipid droplets of the adrenal cortical cells. Both pregnenolone and progesterone act as intermediates in the conversion of cholesterol into steroid hormones. During pregnancy an increased level of plasma cholesterol is known to be associated with an increase of the adrenal corticoid and progesterone. The present study is designed to demonstrate whether the adrenal cortical cells show any dynamic changes during pregnancy.

Practical Picture Processing

1974 ◽  
Vol 32 ◽  
pp. 338-339
Author(s):  
T. A. Welton
Keyword(s):  
Radiation Damage ◽  
Coherence Length ◽  
Spatial Information ◽  
State Of The Art ◽  
Coherent Radiation ◽  
The State ◽  
Energy Spread ◽  
Electron Micrograph ◽  
Picture Processing ◽  
Molecular Skeleton

Various authors have emphasized the spatial information resident in an electron micrograph taken with adequately coherent radiation. In view of the completion of at least one such instrument, this opportunity is taken to summarize the state of the art of processing such micrographs. We use the usual symbols for the aberration coefficients, and supplement these with £ and 6 for the transverse coherence length and the fractional energy spread respectively. He also assume a weak, biologically interesting sample, with principal interest lying in the molecular skeleton remaining after obvious hydrogen loss and other radiation damage has occurred.

Adrenocortical Ultrastructure in Ectopic Acth Syndrome

1976 ◽  
Vol 34 ◽  
pp. 238-239
Author(s):  
K. Kovacs ◽  
E. Horvath ◽  
W. Singer
Keyword(s):  
Adrenal Cortex ◽  
Zona Glomerulosa ◽  
Ectopic Acth Syndrome ◽  
Pituitary Neoplasms ◽  
Electron Microscopic ◽  
Adrenocortical Cells ◽  
Cell Hyperplasia ◽  
Ectopic Acth ◽  
Ectopic Acth Production ◽  
Microscopic Findings

Secretion of ACTH by non-pituitary neoplasms is recognized with increasing frequency. While the clinical and biochemical changes associated with ectopic ACTH production have been extensively studied recently, relatively little attention was focused on the morphology of the adrenal cortex and, to our knowledge, the fine structure of the adrenocortical cells in cases of ectopic ACTH syndrome has not been described so far. We report here the electron microscopic findings in the adrenal cortex of a 50-year-old man with a pancreatic apudoma. The patient showed the characteristic clinical and biochemical features of ectopic ACTH syndrome and because of extensive hypercorticism, underwent bilateral adrenalectomy.By light microscopy, the adrenal cortices showed extensive compact cell hyperplasia and lipid depletion. The zona glomerulosa was present in small foci and, except for a few places, fasciculata cells were noted under the fibrous capsule.

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