Changes in the kidneys in chronic fluorine poisoning

1971 ◽  
Vol 72 (3) ◽  
pp. 1094-1096 ◽  
Author(s):  
A. A. Zhavoronkov ◽  
T. L. Dubynin
Keyword(s):  
Fluorine Poisoning

scholarly journals Incidence of dystrophies caused by fluorine in organs regulated by the parathyroid glands

1944 ◽  
Vol 43 (6) ◽  
pp. 402-408 ◽  
Author(s):  
Leo Spira
Keyword(s):  
Royal Society ◽  
Calcium Metabolism ◽  
The Body ◽  
Parathyroid Glands ◽  
Fluorine Poisoning

Dystrophies due to chronic fluorine poisoning in organs regulated by the parathyroid glands, namely the skin and its appendages, the nails, teeth and hair, and also in bones, are here shown to be unusually common in this country. They should be regarded as easily detectable signs of a serious disturbance of the calcium metabolism of the body. Fluorine is a poison of which the action, in many respects, is similar to that of arsenic. It is the task of the authorities responsible for the health of the nation to search for ways and means capable of minimizing its effect.I wish to express my sincere thanks to the Librarian of the Royal Society of Medicine and his staff for their never-failing courtesy and help.

scholarly journals Some epithelial changes in fluorosis

1944 ◽  
Vol 43 (6) ◽  
pp. 400-401 ◽  
Author(s):  
Leo Spira
Keyword(s):  
Salivary Glands ◽  
Signs And Symptoms ◽  
The Body ◽  
Fluorine Poisoning

Like the skin and its appendages, the teeth, nails and hair, so also other tissues of ectodermal origin are here shown to be affected by fluorine. The action of fluorine consists in lowering the level of the calcium in the blood and tissues. The epithelia of the mouth and the salivary glands, of the nasopharynx, the conjunctivae and the lachrymal glands may be affected. Signs and symptoms are thus produced which are closely similar to those usually attributed primarily to infection. It is suggested that an infection accompanying chronic fluorine poisoning is of a secondary nature, and that it is brought about by the loss of calcium in the body.

Hematological and biochemical studies of fluorine poisoning in chickens, a trial for treatment

1996 ◽  
Vol 88 ◽  
pp. 106
Author(s):  
Abdel Latif Sh. Seddek ◽  
Ahlam Abdel-Hamid ◽  
Thabet A. Ibrahim ◽  
Mahmoud Abd El-Nasser
Keyword(s):  
Biochemical Studies ◽  
Fluorine Poisoning

RNA synthesis in organs of mice with chronic fluorine poisoning

1980 ◽  
Vol 90 (4) ◽  
pp. 1359-1362
Author(s):  
A. P. Avtsyn ◽  
A. A. Zhavoronkov ◽  
L. S. Strochkova
Keyword(s):  
Rna Synthesis ◽  
Fluorine Poisoning

scholarly journals EXPERIMENTAL STUDIES ON THE CHRONIC FLUORINE POISONING

Sangyo Igaku ◽  
1959 ◽  
Vol 1 (7-8) ◽  
pp. 683-690
Author(s):  
Yasuhisa YOSHIDA
Keyword(s):  
Experimental Studies ◽  
Fluorine Poisoning

scholarly journals Fluorine in drinking water

1943 ◽  
Vol 43 (2) ◽  
pp. 142-145 ◽  
Author(s):  
Leo Spira ◽  
F. H. Grimbleby
Keyword(s):  
United States ◽  
Drinking Water ◽  
The United States ◽  
Veterinary Surgeons ◽  
Dental Profession ◽  
Fluorine Poisoning

The modern study of the problem of fluorosis (chronic fluorine poisoning) became possible when an Italian, Stefano Chiaie, described, as quoted by Eager (1901), an unsightly dental dystrophy, now known as ‘mottled teeth’. The efforts to trace its aetiology have been ceaselessly continued ever since, mainly by American investigators. Outstanding amongst these were Black & McKay (1916), pioneers whose researches led to the discovery made by Smith, Lantz & Smith (1931) that it was the fluorine, contained in drinking water, in a concentration of not less than 1 part per million (1 p.p.m.) and ingested during the period of calcification of the teeth, which was the direct cause of the dental dystrophy. This result was soon followed up by a number of observers, mainly in the United States under the leadership of the dental profession, amongst them physiologists, experimental pathologists, pharmacologists, veterinary surgeons, geologists and analytical chemists. The gate for further research, which in view of its magnitude and importance must be considered as being still in its infancy, has thus been thrown wide open.

scholarly journals Mottled Nails. An Early Sign of Fluorosis

1943 ◽  
Vol 43 (1) ◽  
pp. 69-71 ◽  
Author(s):  
Leo Spira
Keyword(s):  
Signs And Symptoms ◽  
Early Sign ◽  
Parathyroid Glands ◽  
Present Communication ◽  
Disturbed Function ◽  
Fluorine Poisoning ◽  
Toe Nails

Signs and symptoms attributed to a disturbed function of the parathyroid glands as a result of the protracted action of small quantities of fluorine have been described elsewhere (Spira, 1942c). It was shown that the lesions on the teeth known as ‘mottled enamel’ were frequently accompanied by lesions on the skin and its appendages, the nails and hair. The object of the present communication is to give some details of the changes produced in the finger- and toe-nails in chronic fluorine poisoning (fluorosis).

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