disturbed function
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2018 ◽  
Vol 142 (5) ◽  
pp. 1229-1238 ◽  
Author(s):  
Kaiyang Liu ◽  
Junrong Cai ◽  
Hongjin Li ◽  
Jingwei Feng ◽  
Chuanbo Feng ◽  
...  

2016 ◽  
Vol 3 (3) ◽  
pp. 116-129 ◽  
Author(s):  
Elena A. Sosnova

In the clinical lecture the polycystic ovary syndrome (PCOS) is considered as the multiple endocrine disease associated with the disturbed function of ovaries, pancreas, adrenalcortex, the hypothalamus and the pituitarygland. The attention is drawn at the modern look at PCOS as a “diagnosis of exclusion”. There is presented information on basic theories of pathogenesis and differential diagnosis of PCOS from other hyperandrogenic conditions. The ultrasound semiotics of polycystic ovaries is reported in details. There are considered opportunities and perspectives of various modalities of therapies of PCOS.


2014 ◽  
Vol 60 (6) ◽  
pp. 38-44
Author(s):  
N G Eneva ◽  
L N Nefedova ◽  
A S Loktionova ◽  
I A Ilovaiskaya ◽  
A I Kim

Modern diagnostics of hypogonadism is based on the results of X-ray and laboratory (biochemical) investigations that reveal the idiopathic form of the disease in the majority of the patients. However, the recent studies have demonstrated a number of genes, whose disturbed function may be responsible for the development of hypogonadism. This creates the prerequisites for the extension of diagnostics of hypogonadism by means of genotyping of the various forms of the pathology in question and thereby may facilitate the choice of the relevant treatment strategy. The present review is focused on the elucidation of the pathogenetic role of candidate genes involved in the development of isolated hypogonadotropic hypogonadism.


2013 ◽  
Vol 128 (2) ◽  
pp. 267-277 ◽  
Author(s):  
Gijs Kooij ◽  
Kathrin Kopplin ◽  
Rosel Blasig ◽  
Marchel Stuiver ◽  
Nathalie Koning ◽  
...  

2012 ◽  
Vol 13 (8) ◽  
pp. 1549-1556 ◽  
Author(s):  
J. Genius ◽  
I. Giegling ◽  
J. Benninghoff ◽  
D. Rujescu

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