Svp-3, a third polymorphic locus for mouse seminal vesicle proteins

1983 ◽  
Vol 21 (7-8) ◽  
pp. 797-800 ◽  
Author(s):  
R. Moutier ◽  
M. F. Bertrand
Keyword(s):  
Seminal Vesicle ◽  
Polymorphic Locus ◽  
Vesicle Proteins

scholarly journals Heterogenous Turnover of Sperm and Seminal Vesicle Proteins in the Mouse Revealed by Dynamic Metabolic Labeling

2012 ◽  
Vol 11 (6) ◽  
pp. M111.014993 ◽  
Author(s):  
Amy J. Claydon ◽  
Steven A. Ramm ◽  
Andrea Pennington ◽  
Jane L. Hurst ◽  
Paula Stockley ◽  
...  
Keyword(s):  
Seminal Vesicle ◽  
Metabolic Labeling ◽  
Vesicle Proteins

Effect of chronic stress on expression and secretion of seminal vesicle proteins in adult rats

Andrologia ◽  
2020 ◽  
Author(s):  
Sitthichai Iamsaard ◽  
Saranya Tongpan ◽  
Supataechasit Yannasithinon ◽  
Supatcharee Arun ◽  
Alexander T. H. Wu ◽  
...  
Keyword(s):  
Seminal Vesicle ◽  
Chronic Stress ◽  
Adult Rats ◽  
Vesicle Proteins

scholarly journals Deletion of a Seminal Gene Cluster Reinforces a Crucial Role of SVS2 in Male Fertility

2019 ◽  
Vol 20 (18) ◽  
pp. 4557 ◽  
Author(s):  
Miyuki Shindo ◽  
Masafumi Inui ◽  
Woojin Kang ◽  
Moe Tamano ◽  
Cai Tingwei ◽  
...  
Keyword(s):  
Seminal Vesicle ◽  
Gene Cluster ◽  
Loxp Site ◽  
Male Mice ◽  
Internal Fertilization ◽  
Immune Attack ◽  
Sperm Membrane ◽  
Encoding Gene ◽  
And Function ◽  
Vesicle Proteins

Multiple genes, whose functions or expression are overlapping, compensate for the loss of one gene. A gene cluster in the mouse genome encodes five seminal vesicle proteins (SVS2, SVS3, SVS4, SVS5, and SVS6). These proteins are produced by male rodents and function in formation of the copulatory plug following mating. SVS2 plays an essential role in the successful internal fertilization by protecting the sperm membrane against a uterine immune attack. We hypothesized that the four remaining seminal vesicle proteins (SVPs) of this gene cluster may partially/completely compensate for the deficiency of SVS2. For confirming our hypothesis, we generated mice lacking the entire SVP-encoding gene cluster and compared their fecundity with Svs2-deficient (Svs2−/−) mice; that is, mice deficient in Svs2 alone. A single loxP site remained after the deletion of the Svs2 gene. Therefore, we inserted another loxP site by combining the CRISPR/Cas9 system with single-stranded oligodeoxynucleotides (ssODN). Male mice lacking the entire SVP-encoding gene cluster (Svs2–6−/− mice) and thereby all five SVP proteins, generated by the deletion of 100kbp genomic DNA, showed low fecundity. However, the fecundity level was comparable with that from Svs2−/− male mice. Our results demonstrate that SVS3, SVS4, SVS5, and SVS6 do not function in the protection of sperm against a uterine immune attack in the absence of SVS2. Thus, Svs2 is the critical gene in the SVP gene cluster.

Evidence for mouse sulfhydryl oxidase‐assisted cross‐linking of major seminal vesicle proteins

2019 ◽  
Vol 86 (11) ◽  
pp. 1682-1693
Author(s):  
Rubhadevi Balu ◽  
Shiyam Sundar Ramachandran ◽  
Sudhakar Gandhi Paramasivam
Keyword(s):  
Seminal Vesicle ◽  
Cross Linking ◽  
Sulfhydryl Oxidase ◽  
Vesicle Proteins

Mouse Seminal Vesicle Proteins

1969 ◽  
Vol 60 (4) ◽  
pp. 187-192 ◽  
Author(s):  
ROBERT D. PLATZ ◽  
H. GLENN WOLFE
Keyword(s):  
Seminal Vesicle ◽  
Vesicle Proteins

scholarly journals Methods for obtaining the enriched fraction of ram seminal vesicle proteins (RSVP14)

2020 ◽  
Vol 49 ◽  
Author(s):  
Bruna Alves Felix ◽  
Kamila de Sousa Otávio ◽  
Jorge André Matias Martins ◽  
Fágner Cavalcante Patrocínio dos Santos ◽  
Ana Luiza Malhado Cazaux de Souza Velho ◽  
...  
Keyword(s):  
Seminal Vesicle ◽  
Vesicle Proteins

scholarly journals Role of high molecular weight seminal vesicle proteins in eliciting the uterine inflammatory response to semen in mice

Reproduction ◽  
1996 ◽  
Vol 107 (2) ◽  
pp. 265-277 ◽  
Author(s):  
S. A. Robertson ◽  
V. J. Mau ◽  
K. P. Tremellen ◽  
R. F. Seamark
Keyword(s):  
Molecular Weight ◽  
Inflammatory Response ◽  
Seminal Vesicle ◽  
High Molecular Weight ◽  
Vesicle Proteins

Electron Microscopic Study of the Epithelium of the Seminal Vesicle of Aging Rats

1974 ◽  
Vol 32 ◽  
pp. 138-139
Author(s):  
V. F. Allison ◽  
G. C. Fink ◽  
G. W. Cearley
Keyword(s):  
Cell Growth ◽  
Epithelial Cell ◽  
Epithelial Cells ◽  
Seminal Vesicle ◽  
Seminal Vesicles ◽  
Epithelial Layer ◽  
Epithelial Hyperplasia ◽  
Electron Microscopic ◽  
Aging Rats ◽  
Pseudostratified Epithelium

It is well known that epithelial hyperplasia (benign hypertrophy) is common in the aging prostate of dogs and man. In contrast, little evidence is available for abnormal epithelial cell growth in seminal vesicles of aging animals. Recently, enlarged seminal vesicles were reported in senescent mice, however, that enlargement resulted from increased storage of secretion in the lumen and occurred concomitant to epithelial hypoplasia in that species.The present study is concerned with electron microscopic observations of changes occurring in the pseudostratified epithelium of the seminal vescles of aging rats. Special attention is given to certain non-epithelial cells which have entered the epithelial layer.

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