Apparent phase-shifts of circadian rhythms (masking effects) during rapid shift rotation

1981 ◽  
Vol 49 (1) ◽  
pp. 53-65 ◽  
Author(s):  
Z. Vokac ◽  
P. Magnus ◽  
E. Jebens ◽  
N. Gundersen
2001 ◽  
Vol 913 (2) ◽  
pp. 165-169 ◽  
Author(s):  
Mark Quigg ◽  
Martin Straume ◽  
Teresa Smith ◽  
Michael Menaker ◽  
Edward H Bertram

Neuroreport ◽  
1995 ◽  
Vol 7 (1) ◽  
pp. 209-212 ◽  
Author(s):  
Elliott G. Marchant ◽  
Ralph E. Mistlberger

1995 ◽  
Vol 695 (2) ◽  
pp. 227-230 ◽  
Author(s):  
Sara J. Eaton ◽  
Niki K. Cote ◽  
Mary E. Harrington

2002 ◽  
Vol 282 (2) ◽  
pp. R454-R463 ◽  
Author(s):  
Katherine M. Sharkey ◽  
Charmane I. Eastman

There has been scant evidence for a phase-shifting effect of melatonin in shift-work or jet-lag protocols. This study tested whether melatonin can facilitate phase shifts in a simulated night-work protocol. Subjects ( n = 32) slept in the afternoons/evenings before night work (a 7-h advance of the sleep schedule). They took melatonin (0.5 mg or 3.0 mg) or placebo before the first four of eight afternoon/evening sleep episodes at a time when melatonin has been shown to phase advance the circadian clock. Melatonin produced larger phase advances than placebo in the circadian rhythms of melatonin and temperature. Average phase advances (±SD) of the dim light melatonin onset were 1.7 ± 1.2 h (placebo), 3.0 ± 1.1 h (0.5 mg), and 3.9 ± 0.5 h (3.0 mg). A measure of circadian adaptation, shifting the temperature minimum enough to occur within afternoon/evening sleep, showed that only subjects given melatonin achieved this goal (73% with 3.0 mg, 56% with 0.5 mg, and 0% with placebo). Melatonin could be used to promote adaptation to night work and jet travel.


1992 ◽  
Vol 598 (1-2) ◽  
pp. 257-263 ◽  
Author(s):  
Johanna H. Meijer ◽  
Benjamin Rusak ◽  
Gabriëlla Gänshirt

1999 ◽  
Vol 19 (15) ◽  
pp. 6637-6642 ◽  
Author(s):  
Mary E. Harrington ◽  
Sabina Hoque ◽  
Adam Hall ◽  
Diego Golombek ◽  
Stephany Biello

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