Cytogenetic analysis of chromosome region 89A of Drosophila melanogaster: isolation of deficiencies and mapping of Po, Aldox-1 and transposon insertions

1992 ◽  
Vol 235 (1) ◽  
pp. 11-21 ◽  
Author(s):  
Catherine R. Nelson ◽  
Paul Szauter
Chromosoma ◽  
1985 ◽  
Vol 92 (5) ◽  
pp. 351-356 ◽  
Author(s):  
Z. M. Biyasheva ◽  
E. S. Belyaeva ◽  
I. F. Zhimulev

Genetics ◽  
1980 ◽  
Vol 94 (1) ◽  
pp. 115-133 ◽  
Author(s):  
Thomas C Kaufman ◽  
Ricki Lewis ◽  
Barbara Wakimoto

ABSTRACT Cytogenetic evidence is presented demonstrating that the 84A-B interval in the proximal portion of the right arm of chromosome 3 is the residence of a homoeotic gene complex similar to the bithorax locus. This complex, originally defined by the Antennapedia (A n t p) mutation, controls segmentation in the anterior portion of the organism. Different lesions within this complex homoeotically transform portions OI the prothorax, proboscis, antenna and eye and present clear analogies to similar lesions within the bithorax locus.


Genome ◽  
1996 ◽  
Vol 39 (4) ◽  
pp. 749-757 ◽  
Author(s):  
James M. Humphreys ◽  
Brenda Duyf ◽  
Mei-Ling A. Joiner ◽  
John P. Phillips ◽  
Arthur J. Hilliker

Mutants of Drosophila melanogaster that lack Cu/Zn superoxide dismutase or urate are hypersensitive to reactive oxygen species (ROS) generated in vivo by the redox-cycling agent paraquat. We have subsequently employed paraquat as a selective agent to identify adult viable mutants potentially defective in other, perhaps unknown, components of ROS metabolism. Paraquat screening of ethyl methanesulfonate-induced second- and third-chromosome mutations yielded 24 paraquat hypersensitive mutants. Two mutants were identified as being new alleles of the previously identified doublesex (dsx) and pink (p) genes. The remainder of the mutations identified previously undescribed genes, including one second chromosome paraquat hypersensitive mutant that was found to exhibit shaking legs, abdomen pulsations, and body shuddering under ether anaesthesia. This recessive mutation was mapped to the polytene chromosome region of 48A5–48B2 and defines a new gene we named quiver (qvr). This mutation is similar in phenotype to the Shaker (Sh), ether-a-gogo (eag), and Hyperkinetic (Hk) mutations, all of which affect potassium channel function in D. melanogaster. Key words : Drosophila, paraquat, EMS-mutagenesis, Shaker, oxidative-stress.


Chromosoma ◽  
1980 ◽  
Vol 81 (2) ◽  
pp. 281-306 ◽  
Author(s):  
E. S. Belyaeva ◽  
M. G. Aizenzon ◽  
V. F. Semeshin ◽  
I. I. Kiss ◽  
K. Koczka ◽  
...  

Gene ◽  
1993 ◽  
Vol 134 (2) ◽  
pp. 175-181 ◽  
Author(s):  
S.I. Baiborodin ◽  
E.M. Baricheva ◽  
S.S. Bogachev ◽  
I.V. Borisevich ◽  
O.V. Strotz ◽  
...  

Genetics ◽  
1983 ◽  
Vol 105 (2) ◽  
pp. 371-386
Author(s):  
Michael A Kotarski ◽  
Sally Pickert ◽  
Ross J MacIntyre

ABSTRACT The chromosomal region surrounding the structural gene for α-glycerophosphate dehydrogenase (αGpdh, 2-20.5) of Drosophila melanogaster has been studied in detail. Forty-three EMS-induced recessive lethal mutations and five previously identified visible mutations have been localized within the 25A-27D region of chromosome 2 by deficiency mapping and in some cases by a recombination analysis. The 43 lethal mutations specify 17 lethal loci. ?Gpdh has been localized to a single polytene chromosome band, 25F5, and there apparently are no lethals that map to the αGpdh locus.


Chromosoma ◽  
1981 ◽  
Vol 84 (2) ◽  
pp. 207-219 ◽  
Author(s):  
E. S. Belyaeva ◽  
I. E. Vlassova ◽  
Z. M. Biyasheva ◽  
V. T. Kakpakov ◽  
G. Richards ◽  
...  

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