Catalase-like crystals in parathyroid gland cells of Rana temporaria L.

1974 ◽  
Vol 153 (2) ◽  
Author(s):  
RainerH. Lange ◽  
A.R. Soames ◽  
Raymond Coleman
2020 ◽  
Vol 26 ◽  
Author(s):  
Wei-han Cao ◽  
Yan-jun Su ◽  
Nian-qiu Liu ◽  
Ying Peng ◽  
Chang Diao ◽  
...  

1881 ◽  
Vol 172 ◽  
pp. 663-711 ◽  

The following paper contains an account of observations upon Rana temporaria, Bufo vulgaris, Triton tœniatus, Triton cristatus,and Coluber natrix . In these animals I have examined the structure of the resting stomach and noted the alterations which occur in it during secretion. I have also estimated the relative amounts of pepsin contained by different portions of the stomach, and the amount of pepsin contained by a definite weight of the gastric mucous membrane in the resting and in the active state. I have further attempted to ascertain whether pepsin exists as such, or in a combined form, in the gland-cells. I do not propose to give a complete account of the structure of the resting stomach in each animal, although certain points in which my observations differ from or extend those of previous observers I may have to treat somewhat fully.


1996 ◽  
Vol 271 (5) ◽  
pp. F1052-F1060 ◽  
Author(s):  
M. Paulais ◽  
M. Baudouin-Legros ◽  
J. Teulon

The effects of extracellular polyvalent cations on the cytosolic free Ca2+ concentration ([Ca2+]i) of isolated segments of the mouse nephron were investigated using fura 2 microfluorometry. Extracellular Ca2+ concentration ([Ca2+]o), gadolinium (Gd3+), and neomycin (Neo) increased the [Ca2+]i in cortical thick ascending limb (CTAL) tubules with effective doses (ED50) of approximately 3.5 mM for Ca2+, 20 microM for Gd3+, and 40 microM for Neo. This effect was reproduced by Ba2+ but not by Mg2+. High [Ca2+]o inhibited the responses to Gd3+, Neo, and Ba2+. The Gd(3+)- and Neo-evoked [Ca2+]i transients persisted in the absence of external Ca2+ and were abolished by the depletion of internal Ca2+ stores with thapsigargin (TG). The responses to rises in [Ca2+]o were similarly inhibited by TG and slightly reduced by 20 microM La3+ but not by 10 microM nifedipine. Mn2+ also mobilized a TG-sensitive internal Ca2+ store and stimulated its own entry. External Ca2+, Gd3+, and Neo induced small but significant increases in [Ca2+]i in distal convoluted tubule, cortical collecting duct, and outer medullary collecting duct segments, transiently increased [Ca2+]i in some medullary TAL (MTAL) tubules, but had no effect on descending thin limb. We conclude that a Ca(2+)-mobilizing Ca2+/polyvalent cation sensor resembling that of the parathyroid gland cells is predominantly located in the mouse CTAL but also in the MTAL and, to a lesser extent, in more distal segments.


1972 ◽  
Vol 127 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Raymond Coleman ◽  
Alan D. Phillips

Author(s):  
S.K. Aggarwal ◽  
J.M. Fadool

Cisplatin (CDDP) a potent antitumor agent suffers from severe toxic side effects with nephrotoxicity being the major dose-limiting factor, The primary mechanism of its action has been proposed to be through its cross-linking DNA strands. It has also been shown to inactivate various transport enzymes and induce hypocalcemia and hypomagnesemia that may be the underlying cause for some of its toxicities. The present is an effort to study its influence on the parathyroid gland for any hormonal changes that control calcium levels in the body.Male Swiss Wistar rats (Crl: (WI) BR) weighing 200-300 g and of 60 days in age were injected (ip) with cisplatin (7mg/kg in normal saline). The controls received saline injections only. The animals were injected (iv) with calcium (0.5 ml of 10% calcium gluconate/day) and were killed by decapitation on day 1 through 5. Trunk blood was collected in heparinized tubes.


1969 ◽  
Vol 124 (4) ◽  
pp. 389-396 ◽  
Author(s):  
L. G. Raisz
Keyword(s):  

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