Platelet labelling with indium-hydroxypyridinone and indium-hydroxypyranone complexes

1994 ◽  
Vol 21 (10) ◽  
Author(s):  
R.D. Abeysinghe ◽  
B.L. Ellis ◽  
R.C. Hider ◽  
J.B. Porter
Keyword(s):  
Platelet Labelling

POSITRON EMISSION TOMOGRAPHY AND PLATELET LABELLING IN THE STUDY OF ATHEROSCLEROSIS

1984 ◽  
Vol 9 (Supplement 9) ◽  
pp. 46
Author(s):  
Y. Yano ◽  
K. H. Brenna ◽  
M. Singh ◽  
J. A. Twitchell ◽  
D. A. Carpenter ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Emission Tomography ◽  
Positron Emission ◽  
Platelet Labelling

MICROEMBOLISATION DURING SURGICAL SHOCK: EFFECT OF PROSTAGLANDIN E1

1987 ◽  
Author(s):  
K R Poskitt ◽  
J T C Irwin ◽  
C M Backhouse ◽  
C N McCollum
Keyword(s):  
Prostaglandin E1 ◽  
Major Surgery ◽  
Midline Laparotomy ◽  
Venous Shunt ◽  
Platelet Labelling ◽  
Platelet Aggregate ◽  
To Receive ◽  
Surgical Shock ◽  
Autologous Platelet ◽  
Postoperative Pulmonary Dysfunction

Embolisation of microaggregates following major surgery may be a cause of pulmonary arterio-venous shunt and postoperative respiratory failure (1). Prostaglandin E1 may prevent intravascular aggregation and we studied this possibility in a pig model of surgical shock.Following autologous platelet labelling with Indium, 16 pigs (20-30kg) were randomised to receive a perioperative infusion of PGE1 (100ng/kg/min) or placebo. Arterial and Swann Ganz catheters were inserted under anaesthesia prior to surgery consisting of midline laparotomy, exteriorisation of small bowel 1.5 hours of aortic clamping and 1 hour of hypotension. On induction, during shock and at 3 days in survivors platelet and leucocyte count, blood radioactivity, venous aggregates (SFP), lung platelet uptake (LPU), pulmonary vascular resistance (PVR) and alveolar-arterial p02 difference (A-ad02) were measured.All results mean ± sem *p <0.05 Mann Whitney U-testDuring surgical shock, the formation of venous aggregates, the fall in circulating radiolabelled platelets and their accumulation in lungs were reduced by PGE1 (p< 0.05). BP, CVP and PWP were all lower on PGE1 and at 3 days the improvement in A-ad02 in PGE1 pigs failed to reach significance.PGE1 reduced platelet aggregate formation and their subsequent pulmonary microembolisation despite worsening shock due to vasodilation.1. McCollum CN, Campbell IT. The value of measuring intravascular platelet aggregation in the prediction of postoperative pulmonary dysfunction. Br J Surg 1979: 66; 703-707

Autologous platelet labelling using “Monovette” vials is not septic

1986 ◽  
Vol 12 (9) ◽  
pp. 471-471
Author(s):  
Helmut Sinzinger ◽  
Eva Strobl-Jäger ◽  
Rudolf Höfer
Keyword(s):  
Platelet Labelling ◽  
Autologous Platelet

Tc-99m HMPAO as a Potential Platelet Labelling Compound: First in Vivo and in Vitro Results

1990 ◽  
pp. 33-44
Author(s):  
W. Becker ◽  
U. Borst ◽  
M. Weppler ◽  
E. P. Kromer ◽  
W. Burner
Keyword(s):  
Platelet Labelling

Platelet Labelling With 111 in — Merc-Usefulness in Renal Transplantation

1990 ◽  
pp. 278-292 ◽  
Author(s):  
C. Piera ◽  
M. Roca ◽  
J. Martin-Comin ◽  
F. Lomena ◽  
J. Mora ◽  
...  
Keyword(s):  
Renal Transplantation ◽  
Platelet Labelling

Platelet Labelling in Atherosclerosis

1991 ◽  
pp. 181-188 ◽  
Author(s):  
Helmut Sinzinger ◽  
Irene Virgolini ◽  
Peter Fitscha
Keyword(s):  
Platelet Labelling
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