scholarly journals Fabrication of Flexible ALN Thin Film-Based Piezoelectric Pressure Sensor for Integration Into an Implantable Artificial Pancreas

Author(s):  
Maria Assunta Signore ◽  
Chiara De Pascali ◽  
Gabriele Rescio ◽  
Alessandro Leone ◽  
Antonietta Taurino ◽  
...  
Proceedings ◽  
2018 ◽  
Vol 2 (13) ◽  
pp. 1037
Author(s):  
Maria Assunta Signore ◽  
Chiara De Pascali ◽  
Gabriele Rescio ◽  
Antonietta Taurino ◽  
Paolo Dario ◽  
...  

Present work reports the fabrication and characterization of a flexible AlN-based piezoelectric pressure sensor integrated, as insulin capsule punching detector, into an implantable artificial pancreas (AP), developed as automated treatment device for Type 1 diabetes. Ti/AlN/Ti trilayer was sputtered on a thin kapton substrate at room temperature, making the final device flexible and sensitive to the forces range of interest (0–4 N). The proposed preliminary prototype of AP comprises a refilling module, interfaced with the intestine wall, able to dock an ingestible insulin capsule. A linearly actuated needle punches the capsule to transfer the insulin to an implanted reservoir. The pressure sensor is located at the connection of the needle with the linear actuator to sense the occurred capsule punching. The sensor waveform output was processed to clearly identify the capsule punching.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
M. A. Signore ◽  
G. Rescio ◽  
C. De Pascali ◽  
V. Iacovacci ◽  
P. Dario ◽  
...  

AbstractThis study reports on the fabrication and characterization of an event detection subsystem composed of a flexible piezoelectric pressure sensor and the electronic interface to be integrated into an implantable artificial pancreas (IAP) for diabetic patients. The developed sensor is made of an AlN layer, sandwiched between two Ti electrodes, sputtered on Kapton substrate, with a preferential orientation along c-axis which guarantees the best piezoelectric response. The IAP is made of an intestinal wall-interfaced refilling module, able to dock an ingestible insulin capsule. A linearly actuated needle punches the duodenum tissue and then the PDMS capsule to transfer the insulin to an implanted reservoir. The device is located at the connection of the needle with the linear actuator to reliably detect the occurred punching of the insulin-filled capsule. Finite Element Analysis (FEA) simulations were performed to evaluate the piezoelectric charge generated for increasing loads in the range of interest, applied on both the sensor full-area and footprint area of the Hamilton needle used for the capsule punching. The sensor-interface circuit was simulated to estimate the output voltage that can be obtained in real operating conditions. The characterization results confirmed a high device sensitivity during the punching, in the low forces (0–4 N) and low actuator speed (2–3 mm/s) ranges of interest, meeting the requirement of the research objective. The choice of a piezoelectric pressure sensor is particularly strategic in the medical field due to the request of self-powered implantable devices which do not need any external power source to output a signal and harvest energy from natural sources around the patient.


Polymers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2133
Author(s):  
Xue Li ◽  
Jun-Yi Sun ◽  
Bin-Bin Shi ◽  
Zhi-Hang Zhao ◽  
Xiao-Ting He

This study is devoted to the design of an elastic polymer thin film-based capacitive wind-pressure sensor to meet the anticipated use for real-time monitoring of structural wind pressure in civil engineering. This sensor is composed of four basic units: lateral elastic deflection unit of a wind-driven circular polymer thin film, parallel plate capacitor with a movable circular electrode plate, spring-driven return unit of the movable electrode plate, and dielectric materials between electrode plates. The capacitance of the capacitor varies with the parallel move of the movable electrode plate which is first driven by the lateral elastic deflection of the wind-driven film and then is, after the wind pressure is reduced or eliminated, returned quickly by the drive springs. The closed-form solution for the contact problem between the wind-driven thin film and the spring-driven movable electrode plate is presented, and its reliability is proved by the experiment conducted. The numerical examples conducted show that it is workable that by using the numerical calibration based on the presented closed-form solution the proposed sensor is designed into a nonlinear sensor with larger pressure-monitoring range and faster response speed than the linear sensor usually based on experimental calibration.


2005 ◽  
Vol 13 ◽  
pp. 111-114
Author(s):  
Lee-Long Han ◽  
Tsing-Tshih Tsung ◽  
Liang-Chia Chen ◽  
Ho Chang ◽  
Ching-Song Jwo

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