Next Generation Biopharmaceuticals: Product Development

2018 ◽  
pp. 253-276 ◽  
Author(s):  
Roman Mathaes ◽  
Hanns-Christian Mahler
Keyword(s):  
Product Development ◽  
Next Generation

Raising the bar in the Mid-Atlantic: Moving MARACOOS observations to next generation forecasting and product development

2012 Oceans ◽  
2012 ◽  
Author(s):  
G. F. Kuska ◽  
C. A. Thoroughgood ◽  
S. Glenn ◽  
M. Crowley ◽  
P. Moore
Keyword(s):  
Product Development ◽  
Next Generation

Improved Product Development Performance through Agile/Stage-Gate Hybrids: The Next-Generation Stage-Gate Process?

2015 ◽  
Vol 58 (1) ◽  
pp. 34-45 ◽  
Author(s):  
Anita Friis Sommer ◽  
Christian Hedegaard ◽  
Iskra Dukovska-Popovska ◽  
Kenn Steger-Jensen
Keyword(s):  
Product Development ◽  
Next Generation ◽  
Generation Stage

A Foundation for Interoperability in Next-Generation Product Development Systems

2000 ◽  
Author(s):  
Simon Szykman ◽  
Steven J. Fenves ◽  
Walid Keirouz ◽  
Steven B. Shooter
Keyword(s):  
Product Development ◽  
Product Information ◽  
Computer Aided Engineering ◽  
Next Generation ◽  
Development Environment ◽  
Feed Forward ◽  
Engineering Software ◽  
Computer Aided ◽  
Cad Cam ◽  
The Cost

Abstract U.S. industry spends billions of dollars as a result of poor interoperability between computer-aided engineering software tools. While ongoing standards development efforts are attempting to address this problem in today’s tools, the more significant demand in next-generation tools will be for representations that allow information used or generated during various product development activities to feed forward and backward into others by way of direct electronic interchange. Although the next generation of tools has the potential for greatly increased benefits, there is also a potential for the cost of poor interoperability to multiply. The goal of this work is to develop representations of information that are unavailable in traditional CAD/CAM/CAE tools to support the exchange of product information in a distributed product development environment. This paper develops a vision of next-generation product development systems and provides a core representation for product development information on which future systems can be built.

Next Generation CANDU Performance Assurance

2002 ◽  
Author(s):  
David J. Wren ◽  
P. J. Allsop ◽  
J. M. Hopwood
Keyword(s):  
Product Development ◽  
Large Scale ◽  
Low Cost ◽  
Development Program ◽  
Next Generation ◽  
Customer Expectations ◽  
Generation Plant ◽  
Reliable Performance ◽  
And Performance ◽  
Under Construction

AECL is developing a next generation CANDU design to meet market requirements for low cost, reliable energy supplies. The primary product development objective is to achieve a capital cost substantially lower than the current nuclear plant costs, such that the next generation plant will be competitive with alternative options for large-scale base-load electricity supply. However, other customer requirements, including safety, low-operating costs and reliable performance, are being addressed as equally important design requirements. The main focus of this paper is to address the development directions that will provide performance assurance. The next generation CANDU is an evolutionary extension of the proven CANDU 6 design. There are eight CANDU 6 units in operation in four countries around the world and further three units are under construction. These units provide a sound basis for projecting highly reliable performance for the next generation CANDU. In addition, the next generation CANDU program includes development and qualification activities that will address the new features and design extensions in the advanced plant. To limit product development risk and to enhance performance assurance, the next generation CANDU design features and performance parameters have been carefully reviewed during the concept development phase and have been deliberately selected so as to be well founded on the existing CANDU knowledge base. Planned research and development activities are required only to provide confirmation of the projected performance within a modest extension of the established database. Necessary qualification tests will be carried out within the timeframe of the development program, to establish a proven design prior to the start of a construction project. This development support work coupled with ongoing AECL programs to support and enhance the performance and reliability of the existing CANDU plants will provide sound assurance that the next generation CANDU plants will meet customer expectations.

SHARE: A METHODOLOGY AND ENVIRONMENT FOR COLLABORATIVE PRODUCT DEVELOPMENT

1994 ◽  
Vol 03 (02) ◽  
pp. 129-153 ◽  
Author(s):  
GEORGE TOYE ◽  
MARK R. CUTKOSKY ◽  
LARRY J. LEIFER ◽  
J. MARTY TENENBAUM ◽  
JAY GLICKSMAN
Keyword(s):  
Product Development ◽  
Design Process ◽  
Information Technologies ◽  
The Internet ◽  
Shared Understanding ◽  
Design Teams ◽  
Next Generation ◽  
Collaborative Product Development ◽  
Design Projects ◽  
Formal Design

The SHARE project seeks to apply information technologies in helping design teams gather, organize, re-access, and communicate both informal and formal design information to establish a "shared understanding" of the design and design process. This paper presents the visions of SHARE, along with the research and strategies undertaken to build an infrastructure toward its realization. A preliminary prototype environment is being used by designers working on a variety of industry sponsored design projects. This testbed continues to inform and guide the development of NoteMail, MovieMail, and Xshare, as well as other components of the next generation SHARE environment that will help distributed design teams work together more effectively on the Internet.

The Role of Knowledge in Next-generation Product Development Systems

2000 ◽  
Vol 1 (1) ◽  
pp. 3-11 ◽  
Author(s):  
Simon Szykman ◽  
Ram D. Sriram ◽  
William C. Regli
Keyword(s):  
Product Development ◽  
Next Generation ◽  
Engineering Product ◽  
Survey Paper ◽  
Research Areas ◽  
Recent Developments ◽  
Industry Practice ◽  
Representative Selection ◽  
Selection Of

Information technology has played an increasingly important role in engineering product development. Its influence over the past decade has been accelerating and its impact in the coming decade will undoubtedly be immense. This paper surveys several research areas relating to knowledge representation, capture and retrieval, which will have a growing influence on product development. Each of these areas could, on its own, provide sufficient material for an entire survey paper. Unlike traditional survey papers, this paper does not attempt to provide a comprehensive review of a field of research from its inception to the present. Rather, this paper aims to touch on a representative selection of recent developments in these influential technical areas. The paper provides perspectives into the kinds of technologies that are emerging from rapidly expanding fields of research, and discusses challenges that must be overcome to enable transition of these technologies into industry practice to support the next generation of product development software tools.

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