C8H8S, Phenyl vinyl sulfide

Author(s):  
G. Graner ◽  
E. Hirota ◽  
T. Iijima ◽  
K. Kuchitsu ◽  
D. A. Ramsay ◽  
...  
Keyword(s):  
2003 ◽  
pp. 124-124
Author(s):  
Daniel S. Reno ◽  
Richard J. Pariza
Keyword(s):  

Pharmaceutics ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 462 ◽  
Author(s):  
Kim ◽  
Alle ◽  
Kim

Poly(hydroxyethyl acrylate-co-phenyl vinyl sulfide) (P(HEA-co-PVS)), as an oxidizable amphiphilic polymer, was prepared for the fabrication of an oxidation- and temperature-responsive micelle for the delivery of doxorubicin (DOX). The interfacial activity of H2O2-treated P(HEA-co-PVS) was significantly lower than that of the untreated variety, possibly because of the oxidization of PVS. P(HEA-co-PVS) exhibited a lower critical solution temperature (LCST) behavior and the LCST increased upon H2O2 treatment. The copolymer micelles, prepared by the dialysis method, were found to be round particles (less than 100 nm) on TEM micrograph. The release degree of Nile red loaded in the micelles was higher when the H2O2 concentration was higher, possibly because the micelles could be solubilized more readily at a higher H2O2 concentration. The release degree was more strongly dependent on the oxidizing agent concentration when the temperature was higher. DOX loaded in the micelles suppressed the in vitro growth of KB cells (a human cancer cell type originating from the cervix) much more effectively than DOX loaded in an unoxidizable control micelle and free DOX, possibly because the copolymer would undergo an increase in its LCST, lose its amphiphilic property, and the micelles would be disassembled. The DOX-loaded micelles were readily internalized into KB cells, as evidenced by flow cytometry (FACS) and confocal laser scanning microscopy (CLSM).


1982 ◽  
Vol 27 (5) ◽  
pp. 1849-1851
Author(s):  
Muneaki Tomiyama ◽  
Shuji Kondo ◽  
Kazuichi Tsuda

1991 ◽  
Vol 24 (18) ◽  
pp. 5009-5014 ◽  
Author(s):  
Shouji Iwatsuki ◽  
Masataka Kubo ◽  
Makoto Wakita ◽  
Yasue Matsui ◽  
Hideki Kanoh
Keyword(s):  

RSC Advances ◽  
2014 ◽  
Vol 4 (38) ◽  
pp. 19794-19799 ◽  
Author(s):  
Omar Boutureira ◽  
M. Isabel Matheu ◽  
Yolanda Díaz ◽  
Sergio Castillón

Microwave irradiation effectively accelerates the cross-metathesis reaction of 2-deoxy-d-ribose hydroxyalkene and derivatives with electron-rich phenyl vinyl sulfide using commercially available ruthenium-based catalysts, thus providing a flexible metal-mediated route to 2,3-dideoxy-d-ribopyranose ring system donors.


Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 1116
Author(s):  
Vladimir A. Potapov ◽  
Roman S. Ishigeev ◽  
Svetlana V. Amosova

Regioselective synthesis of novel 2H,3H-[1,4]thiazino[2,3,4-ij]quinolin-4-ium derivatives has been developed by annulation reactions of 8-quinolinesulfenyl halides with vinyl chalcogenides (vinyl ethers, divinyl sulfide, divinyl selenide and phenyl vinyl sulfide) and tetravinyl silane. The novel reagent 8-quinolinesulfenyl bromide was used in the annulation reactions. The influence of the substrate structure and the nature of heteroatoms on the direction of the reactions and on product yields has been studied. The opposite regiochemistry was observed in the reactions with vinyl chalcogenides and tetravinyl silane. The obtained condensed heterocycles are novel water-soluble functionalized compounds with promising biological activity.


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