Protective effect of l -arginine against stress-induced gastric mucosal lesions in rats and its relation to nitric oxide-mediated inhibition of neutrophil infiltration

2001 ◽  
Vol 43 (6) ◽  
pp. 535-541 ◽  
Author(s):  
Yoshiji Ohta ◽  
Keiji Nishida
Keyword(s):  
Nitric Oxide ◽  
Protective Effect ◽  
Neutrophil Infiltration ◽  
Gastric Mucosal Lesions ◽  
Mucosal Lesions

scholarly journals Protective Effect of Repeatedly Preadministered Brazilian Propolis Ethanol Extract against Stress-Induced Gastric Mucosal Lesions in Rats

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Tadashi Nakamura ◽  
Yoshiji Ohta ◽  
Kumiko Ikeno ◽  
Koji Ohashi ◽  
Takeyuki Ikeno
Keyword(s):  
Protective Effect ◽  
Restraint Stress ◽  
Wistar Rats ◽  
Water Immersion ◽  
Ethanol Extract ◽  
Neutrophil Infiltration ◽  
Gastric Mucosal Lesions ◽  
Male Wistar Rats ◽  
Mucosal Lesions ◽  
Brazilian Propolis

The present study was conducted to clarify the protective effect of Brazilian propolis ethanol extract (BPEE) against stress-induced gastric mucosal lesions in rats. The protective effect of BPEE against gastric mucosal lesions in male Wistar rats exposed to water-immersion restraint stress (WIRS) for 6 h was compared between its repeated preadministration (50 mg/kg/day, 7 days) and its single preadministration (50 mg/kg). The repeated BPEE preadministration attenuated WIRS-induced gastric mucosal lesions and gastric mucosal oxidative stress more largely than the single BPEE preadministration. In addition, the repeated BPEE preadministration attenuated neutrophil infiltration in the gastric mucosa of rats exposed to WIRS. The protective effect of the repeated preadministration of BPEE against WIRS-induced gastric mucosal lesions was similar to that of a single preadministration of vitamin E (250 mg/kg) in terms of the extent and manner of protection. From these findings, it is concluded that BPEE preadministered in a repeated manner protects against gastric mucosal lesions in rats exposed to WIRS more effectively than BPEE preadministered in a single manner possibly through its antioxidant and anti-inflammatory actions.

scholarly journals Protective Effect of Taurine against Ammonia-Induced Gastric Mucosal Lesions in Rats

1989 ◽  
Vol 51 (4) ◽  
pp. 569-571
Author(s):  
Motonobu MURAKAMI ◽  
Jung Keun YOO ◽  
Sanae TERAMURA ◽  
Ko YAMAMOTO ◽  
Hiroshi SAITA ◽  
...  
Keyword(s):  
Protective Effect ◽  
Gastric Mucosal Lesions ◽  
Mucosal Lesions

scholarly journals Protective effect of paracetamol on stress-induced gastric mucosal lesions in rats.

1994 ◽  
Vol 64 ◽  
pp. 87
Author(s):  
Hideshi Omura ◽  
Kazuhisa Maeda ◽  
Masahiko Ishimura ◽  
Yoshinori Kamisaki ◽  
Tadao Itoh
Keyword(s):  
Protective Effect ◽  
Gastric Mucosal Lesions ◽  
Mucosal Lesions

scholarly journals Nitric Oxide Donating Compounds Inhibit HCl-Induced Gastric Mucosal Lesions Mainly via Prostaglandin

2001 ◽  
Vol 85 (2) ◽  
pp. 133-138 ◽  
Author(s):  
Masayuki Uchida ◽  
Kei Matsueda ◽  
Ryosuke Shoda ◽  
Akira Muraoka ◽  
Shigeru Yamato
Keyword(s):  
Nitric Oxide ◽  
Gastric Mucosal Lesions ◽  
Mucosal Lesions

Effect of nitric oxide on gastric mucosal lesions induced by water-immersion-restraint stress

2000 ◽  
Vol 118 (4) ◽  
pp. A1244
Author(s):  
Hiroshi Hashimoto ◽  
Akiko Yanagisawa ◽  
Masumi Akimoto ◽  
Mutsuo Shigemoto ◽  
Katsuko Yamashita
Keyword(s):  
Nitric Oxide ◽  
Restraint Stress ◽  
Water Immersion ◽  
Gastric Mucosal Lesions ◽  
Water Immersion Restraint Stress ◽  
Mucosal Lesions
Sign in / Sign up

Export Citation Format

Share Document