Vasopressin V1a Receptor Signaling in a Rat Choroid Plexus Cell Line

2000 ◽  
Vol 275 (2) ◽  
pp. 322-327 ◽  
Author(s):  
T. Battle ◽  
L. Preisser ◽  
V. Marteau ◽  
G. Meduri ◽  
M. Lambert ◽  
...  
Keyword(s):  
Choroid Plexus ◽  
Cell Line ◽  
Receptor Signaling ◽  
V1a Receptor ◽  
Plexus Cell ◽  
Vasopressin V1a Receptor

Glucagon and vasopressin V1a receptor signaling in hepatocytes from aging rats

2001 ◽  
Vol 122 (4) ◽  
pp. 385-400 ◽  
Author(s):  
L. Teillet ◽  
S. Gouraud ◽  
L. Preisser ◽  
T. Tordjmann ◽  
A. Morel ◽  
...  
Keyword(s):  
Receptor Signaling ◽  
Aging Rats ◽  
V1a Receptor ◽  
Vasopressin V1a Receptor

Serotonin, bradykinin and endothelin signalling in a sheep choroid plexus cell line

Life Sciences ◽  
1999 ◽  
Vol 64 (10) ◽  
pp. 859-867 ◽  
Author(s):  
Olivier Albert ◽  
Nicolas Ancellin ◽  
Laurence Preisser ◽  
Alain Morel ◽  
Bruno Corman
Keyword(s):  
Choroid Plexus ◽  
Cell Line ◽  
Plexus Cell

scholarly journals Activation of TRPV4 stimulates transepithelial ion flux in a porcine choroid plexus cell line

2018 ◽  
Vol 315 (3) ◽  
pp. C357-C366 ◽  
Author(s):  
Daniel Preston ◽  
Stefanie Simpson ◽  
Dan Halm ◽  
Alexandra Hochstetler ◽  
Christian Schwerk ◽  
...  
Keyword(s):  
Choroid Plexus ◽  
Cell Line ◽  
Transient Receptor Potential ◽  
Water Movement ◽  
Receptor Potential ◽  
Ion Flux ◽  
Transient Receptor Potential Vanilloid ◽  
Junctional Complexes ◽  
Plexus Cell ◽  
Transient Receptor

The choroid plexus (CP) epithelium plays a major role in the production of cerebrospinal fluid (CSF). A polarized cell line, the porcine CP-Riems (PCP-R) line, which exhibits many of the characteristics of the native epithelium, was used to study the effect of activation of the transient receptor potential vanilloid 4 (TRPV4) cation channel found in the PCP-R cells as well as in the native epithelium. Ussing-style electrophysiological experiments showed that activation of TRPV4 with a specific agonist, GSK1016790A, resulted in an immediate increase in both transepithelial ion flux and conductance. These changes were inhibited by either of two distinct antagonists, HC067047 or RN1734. The change in conductance was reversible and did not involve disruption of epithelial junctional complexes. Activation of TRPV4 results in Ca2+ influx, therefore, we examined whether the electrophysiological changes were the result of secondary activation of Ca2+-sensitive channels. PCP-R cells contain two Ca2+-activated K+ channels, the small conductance 2 (SK2) and the intermediate conductance (IK) channels. Based on inhibitor studies, the former is not involved in the TRPV4-mediated electrophysiological changes whereas one of the three isoforms of the IK channel (KCNN4c) may play a role in the apical secretion of K+. Blocking the activity of this IK isoform with TRAM34 inhibited the TRPV4-mediated change in net transepithelial ion flux and the increased conductance. These studies implicate TRPV4 as a hub protein in the control of CSF production through stimulation by multiple effectors resulting in transepithelial ion and subsequent water movement.

Sex Hormones Protect Against Amyloid-β Induced Oxidative Stress in the Choroid Plexus Cell Line Z310

2016 ◽  
Vol 28 (9) ◽  
Author(s):  
A. R. Costa ◽  
H. Marcelino ◽  
I. Gonçalves ◽  
T. Quintela ◽  
J. Tomás ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Choroid Plexus ◽  
Cell Line ◽  
Sex Hormones ◽  
Amyloid Β ◽  
Plexus Cell

Proteomic analysis of mouse choroid plexus cell line ECPC-4 treated with lipid A

2016 ◽  
Vol 65 (4) ◽  
pp. 295-302 ◽  
Author(s):  
Masaoki Takano ◽  
Mieko Otani ◽  
Takahiro Kaji ◽  
Keiji Sano ◽  
Michiko Hamada-Kanazawa ◽  
...  
Keyword(s):  
Choroid Plexus ◽  
Cell Line ◽  
Proteomic Analysis ◽  
Lipid A ◽  
Plexus Cell

Lipopolysaccharide activates the kallikrein–kinin system in mouse choroid plexus cell line ECPC4

2008 ◽  
Vol 434 (3) ◽  
pp. 310-314 ◽  
Author(s):  
Masaoki Takano ◽  
Chieko Satoh ◽  
Naomi Kunimatsu ◽  
Mieko Otani ◽  
Michiko Hamada-Kanazawa ◽  
...  
Keyword(s):  
Choroid Plexus ◽  
Cell Line ◽  
Kinin System ◽  
Plexus Cell ◽  
Kallikrein Kinin System

scholarly journals Mechanisms of subcellular cytosolic Ca2+ signaling evoked by stimulation of the vasopressin V1a receptor

1992 ◽  
Vol 267 (32) ◽  
pp. 23282-23289 ◽  
Author(s):  
M.H. Nathanson ◽  
M.S. Moyer ◽  
A.D. Burgstahler ◽  
A.M. O'Carroll ◽  
M.J. Brownstein ◽  
...  
Keyword(s):  
V1a Receptor ◽  
Vasopressin V1a Receptor ◽  
Stimulation Of
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