Antioxidant Effects of an Aqueous Extract of Ilex paraguariensis

2000 ◽  
Vol 269 (2) ◽  
pp. 357-360 ◽  
Author(s):  
G.R. Schinella ◽  
G. Troiani ◽  
V. Dávila ◽  
P.M. de Buschiazzo ◽  
H.A. Tournier
Keyword(s):  
Aqueous Extract ◽  
Ilex Paraguariensis ◽  
Antioxidant Effects

scholarly journals Reduction in oxidative stress levels in the colonic mucosa without fecal stream after the application of enemas containing aqueous Ilex paraguariensis extract

2011 ◽  
Vol 26 (4) ◽  
pp. 289-296 ◽  
Author(s):  
Fernando Lorenzetti da Cunha ◽  
Camila Morais Gonçalves da Silva ◽  
Marcos Gonçalves de Almeida ◽  
Thais Miguel do Monte Lameiro ◽  
Letícia Helena Souza Marques ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Aqueous Extract ◽  
Tissue Damage ◽  
Colonic Mucosa ◽  
Ilex Paraguariensis ◽  
Histopathological Analysis ◽  
Fecal Stream ◽  
Proximal Colostomy ◽  
Antioxidant Effects ◽  
Experimental Group

PURPOSE: To evaluate the antioxidant effects of enemas containing aqueous extract of Ilex paraguariensis, comparing segments with and without fecal stream and correlating the segments with the duration of intervention. METHODS: Twenty-six Wistar rats were subjected to a diversion of the fecal stream in the left colon by a proximal colostomy and distal mucosal fistula. The rats were distributed randomly into two experimental groups of 13 animals each based on the time of sacrifice after surgical procedure (two or four weeks). Each group was then divided into two experimental subgroups that received either second daily enemas containing 0.9% saline solution or aqueous extract of Ilex paraguariensis at 0.2g/100g. Colitis was diagnosed by histopathological analysis and the detection of oxidative tissue damage by measuring the levels of malondialdehyde. The Mann-Whitney test was used to compare the tissue levels of malondialdehyde between colon segments with and without fecal stream in each experimental group, and the Kruskal-Wallis test was used to verify the variance between the levels of oxidative stress according the duration of the irrigation; both tests determined significance at 5% (p<0.05). RESULTS: The levels of malondialdehyde in the animals subjected to intervention in the colon with saline with and without fecal stream after two and four weeks of irrigation were 0.05±0.006 and 0.06±0.006, and 0.05± 0.03 and 0.08 ±0.02, respectively. The malondialdehyde levels in the animals irrigated with Ilex paraguariensis with and without fecal stream after two and four weeks of irrigation were 0.010±0.002 and 0.02±0.004, and 0.03±0.007 and 0.04±0.01, respectively. After two and four weeks of intervention, the levels of malondialdehyde were lower in the animals irrigated with Ilex paraguariensis regardless of the time of irrigation (p=0.0001 and p=0.002, respectively). CONCLUSION: The daily rectal application of enemas containing aqueous extract of Ilex paraguariensis decreases oxidative tissue damage in the colon without fecal stream regardless of the time of irrigation.

Aqueous extract of Ilex paraguariensis decreases nucleotide hydrolysis in rat blood serum

2005 ◽  
Vol 97 (1) ◽  
pp. 73-77 ◽  
Author(s):  
Milena Görgen ◽  
Kátia Turatti ◽  
Afonso R. Medeiros ◽  
Andréia Buffon ◽  
Carla D. Bonan ◽  
...  
Keyword(s):  
Blood Serum ◽  
Aqueous Extract ◽  
Ilex Paraguariensis ◽  
Nucleotide Hydrolysis ◽  
Rat Blood

Antioxidant Effects of Aqueous Extract of Sweet Potato and Ascorbic Acid on Paracetamol Induced Damage

2005 ◽  
Vol 6 (1) ◽  
pp. 87-92
Author(s):  
A.O. Lawal . ◽  
A. Ologundudu . ◽  
F.O. Obi . ◽  
I.V. Ogungbe . ◽  
A.O. Olakanye . ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Sweet Potato ◽  
Aqueous Extract ◽  
Antioxidant Effects

The effect of aqueous extract of gross and commercial yerba mate (Ilex paraguariensis) on intra-abdominal and epididymal fat and glucose levels in male Wistar rats

Fitoterapia ◽  
2011 ◽  
Vol 82 (6) ◽  
pp. 818-826 ◽  
Author(s):  
Raquel D'Agostini Silva ◽  
Audrin Loss Scopel Bueno ◽  
Carin Weirich Gallon ◽  
Luana Ferreira Gomes ◽  
Samuel Kaiser ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
Wistar Rats ◽  
Ilex Paraguariensis ◽  
Yerba Mate ◽  
Glucose Levels ◽  
Epididymal Fat ◽  
Male Wistar Rats

scholarly journals Evaluation of the antitumor and antioxidant effects of jatobá (Hymenaea courbaril) extracts / Avaliação do efeito antitumoral e antioxidante de extratos do jatobá (Hymenaea courbaril)

2021 ◽  
Vol 7 (12) ◽  
pp. 116001-116018
Author(s):  
Elisângela Miranda de Jesus Lisboa ◽  
Lucinéia Reuse Albiero ◽  
Nadila Melchiors ◽  
Wesley Sandro de Paula Borges ◽  
Valfran da Silva Lima ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Aqueous Extract ◽  
Reduced Glutathione ◽  
Tumor Development ◽  
Thiobarbituric Acid ◽  
Renal Tissue ◽  
Ehrlich Carcinoma ◽  
Thiobarbituric Acid Reactive Substances ◽  
Hymenaea Courbaril ◽  
Antioxidant Effects

Ethnobotanical surveys have revealed the use of jatobá for the treatment of several diseases. This study determined the effect of plant extracts on the development of Ehrlich carcinoma. Male Swiss mice (n=6) were subcutaneously inoculated with 106 tumor cells and intragastrically administered ethanol (2 mg·mL-1, 5 mg·mL-1, or 10 mg·mL-1) or aqueous extracts of jatobá seed or bark for 90 days. Tumor development did not significantly differ between the groups studied; however, animals treated with the aqueous extract of the seed (2.205 mg·mL-1) had a reduction in tumor size compared to those treated with the aqueous extract of the bark (1.7 mg·mL-1). The treatment was not found to influence the survival of the animals studied. A new group of animals (n=7), with or without the tumor, received the aqueous extract of jatobá seed for 7, 14, and 30 days to evaluate oxidative stress. The extract reduced the thiobarbituric acid reactive substances levels at 7 days in the liver and kidneys, and 14 days in brain and renal tissue. Protein carbonylation levels were also reduced at 7 days in the liver and brain tissue and 14 days in the liver. The reduced glutathione levels diminished in animals treated for 7 and 14 days. We conclude that treatment with the aqueous extract of the jatobá seed presents promising activity in the reduction of oxidative stress.

Antihyperglycemic Effect of the Aqueous Extract of Foeniculum vulgare in Normal and Streptozotocin-induced Diabetic Rats

2020 ◽  
Vol 20 (1) ◽  
pp. 54-63
Author(s):  
Fadwa El-Ouady ◽  
Nadia Lahrach ◽  
Mohammed Ajebli ◽  
Ahmed E. Haidani ◽  
Mohamed Eddouks
Keyword(s):  
Blood Glucose ◽  
Aqueous Extract ◽  
Diabetic Rats ◽  
Diabetic Rat ◽  
Oral Glucose ◽  
Foeniculum Vulgare ◽  
High Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Antioxidant Effects

Background: Diabetes mellitus is associated with high blood glucose levels due to insulin shortcoming (insulinopenia) or defective insulin action. The objective of the study was to investigate the antidiabetic and antioxidant effects of Foeniculum vulgare in streptozotocin-induced diabetic rat. Methods: The effects of the leaves aqueous extract (LAE) of Foeniculum vulgare (F. vulgare) at a dose of 10 mg/kg on blood glucose levels were evaluated in normal and streptozotocin (STZ)- induced diabetic rats. Histopathological changes were also evaluated in liver in STZ-induced rats. Results: Single oral administration of F. vulgare LAE reduced blood glucose levels 6 h after administration in STZ diabetic rats (p<0.0001). Furthermore, blood glucose levels were decreased in both normal (p<0.05) and STZ diabetic rats (p<0.0001) after the fifteenth day of treatment. During this test, both groups did not show any significant change in their body weight. Moreover, this aqueous extract improved oral glucose tolerance in diabetic rats and revealed a positive effect on liver histology. On the other hand, the extract used in this experiment showed an inhibitory concentration (IC50) of 50% of free radicals with a concentration of 43±1.19 µg/ml. While the synthetic antioxidant (BHT) had an IC50 equal to 22.67±2.17µg /ml. Conclusion: This study demonstrates the antihyperglycemic, hypoglycemic and antioxidant effects of the leaves of F. vulgare in normal and diabetic rats.

Antihyperglycemic potential of Matricaria pubescens(Desf.) Schultz. in streptozotocin-induced diabetic rats

2020 ◽  
Vol 20 ◽  
Author(s):  
Ayoub Amssayef ◽  
Mohammed Ajebli ◽  
Mohamed Eddouks
Keyword(s):  
Aqueous Extract ◽  
Aerial Part ◽  
Histopathological Examination ◽  
Diabetic Rats ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Liver And Pancreas ◽  
Treatment Of Diabetes ◽  
Antioxidant Effects

Aims: The aim of the study was to investigate the antihyperglycemic activity of Matricaria pubescens. Background: Matricaria pubescens (Def). Shultz (Asteraceae) is commonly used traditionally for the treatment of diabetes in Morocco. Objective: This present investigation aimed to assess the antihyperglycemic and antioxidant effects of the aqueous extract of aerial part of Matricaria pubescens (M. pubescens). Methods: The effect of a single and repeated oral administration of the aqueous extract of aerial part of M. pubescens (AEAPMP) at a dose of 40 mg/kg on glucose was examined in normal and streptozotocin-induced diabetic rats. Additionally, histopathological examination of pancreas and liver was carried out according to the Hematoxylin-Eosin method. The antioxidant activity was performed using the DPPH assay. Results: The results showed that the aqueous extract of M. pubescens (AEAPMP) exhibited a significant lowering activity on blood glucose levels in STZ-induced diabetic rats. In addition, AEAPMP ameliorated the histopathological tissues of liver and pancreas. Furthermore, a potential in vitro antioxidant of AEAPMP has been shown. Conclusion: In conclusion, this study demonstrates that M. pubescens possesses a beneficial effect against hyperglycemia associated with diabetes.

Yerba Maté (Ilex paraguariensis) Aqueous Extract Decreases Intestinal SGLT1 Gene Expression but Does Not Affect Other Biochemical Parameters in Alloxan-Diabetic Wistar Rats

2008 ◽  
Vol 56 (22) ◽  
pp. 10527-10532 ◽  
Author(s):  
Daniela M. Oliveira ◽  
Helayne S. Freitas ◽  
Marina F. F. Souza ◽  
Demetrius P. Arçari ◽  
Marcelo L. Ribeiro ◽  
...  
Keyword(s):  
Gene Expression ◽  
Aqueous Extract ◽  
Biochemical Parameters ◽  
Wistar Rats ◽  
Ilex Paraguariensis
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