scholarly journals OP13.03: Gastroschisis: Fetal biometry and intrauterine growth patterns

2008 ◽  
Vol 32 (3) ◽  
pp. 351-352
Author(s):  
A. L. Horton ◽  
M. S. Powell ◽  
L. C. Messer ◽  
H. M. Wolfe
PEDIATRICS ◽  
1966 ◽  
Vol 37 (3) ◽  
pp. 403-408 ◽  
Author(s):  
Lula O. Lubchenco ◽  
Charlotte Hansman ◽  
Edith Boyd

Charts of intrauterine growth in length, weight-length ratio and head circumference as estimated from liveborn measurements are presented. These, in conjunction with intrauterine weight charts, permit the identification of infants with unusual intrauterine growth patterns.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Alison Chu ◽  
Yasmeen Dhindsa ◽  
Myung Shin Sim ◽  
Marie Altendahl ◽  
Irena Tsui

Abstract Low birthweight and decreased postnatal weight gain are known predictors of worse retinopathy of prematurity (ROP) but the role of prenatal growth patterns in ROP remains inconclusive. To distinguish small for gestational age (SGA) from intrauterine growth restriction (IUGR) as independent predictors of ROP, we performed a retrospective cohort study of patients who received ROP screening examinations at a level IV neonatal intensive care unit over a 7-year period. Data on IUGR and SGA status, worst stage of and need for treatment for ROP, and postnatal growth was obtained. 343 infants were included for analysis (mean gestational age = 28.6 weeks and birth weight = 1138.2 g). IUGR infants were more likely to have a worse stage of ROP and treatment-requiring ROP (both p < 0.0001) compared to non-IUGR infants. IUGR infants were more likely to be older at worst stage of ROP (p < 0.0001) and to develop postnatal growth failure (p = 0.01) than non-IUGR infants. Independent of postnatal growth failure status, IUGR infants had a 4–5 × increased risk of needing ROP treatment (p < 0.001) compared to non-IUGR infants. SGA versus appropriate for gestational age infants did not demonstrate differences in retinopathy outcomes, age at worst ROP stage, or postnatal growth failure. These findings emphasize the importance of prenatal growth on ROP development.


2017 ◽  
Vol 50 ◽  
pp. 90-90 ◽  
Author(s):  
T. Maric ◽  
C. Kanu ◽  
D. Muller ◽  
I. Tzoulaki ◽  
M. Johnson ◽  
...  

2017 ◽  
Vol 102 (3) ◽  
pp. 1059-1066 ◽  
Author(s):  
Tanja G. M. Vrijkotte ◽  
E. Jessica Hrudey ◽  
Marcel B. Twickler

Abstract Background: Intrauterine growth patterns are influenced by maternal thyroid function during gestation and by fetal sex. It is unknown, however, whether the relationships between maternal thyrotropin (TSH) and free thyroxine (fT4) levels in early pregnancy and fetal growth outcomes are modified by fetal sex. Design: Data were obtained from a community-based cohort study of pregnant women living in Amsterdam (Amsterdam Born Children and Their Development study). TSH and fT4 levels were determined during the first prenatal screening at median 13 weeks (interquartile range, 12 to 14). Women with live-born singletons and no overt thyroid dysfunction were included (N = 3988). Associations between these maternal hormones and birth weight, small for gestational age (SGA), and large for gestational age (LGA) were analyzed separately for each sex. Results: After adjustments, 1 pmol/L increase in maternal fT4 levels was associated with a reduction in birth weight of 33.7 g (P &lt; 0.001) in male newborns and 16.1 g (P &lt; 0.05) in female newborns. Increased maternal fT4 was not associated with increased odds for SGA, but was associated with a decreased odds for LGA in boys [per 1 pmol/L; odds ratio (OR), 0.79; 95% confidence interval (CI), 0.69 to 0.90]. Maternal subclinical hypothyroidism in early pregnancy (TSH &gt; 2.5 mU/L, 7.3%) was associated with increased odds for LGA in male newborns (OR, 1.95; 95% CI, 1.22 to 3.11). Conclusion: Maternal fT4 in early pregnancy was observed to be inversely associated with birth weight, with a stronger relationship in males. Male infants also had increased odds for LGA in mothers with subclinical hypothyroidism. Sexual dimorphism appears to be present in the relationship between maternal thyroid metabolism and fetal intrauterine growth, with stronger associations in male infants.


2009 ◽  
Vol 27 (03) ◽  
pp. 211-217 ◽  
Author(s):  
Amanda Horton ◽  
Marcy Powell ◽  
Honor Wolfe

2013 ◽  
Vol 32 (1) ◽  
pp. 35-43 ◽  
Author(s):  
Nir Melamed ◽  
Israel Meizner ◽  
Reuven Mashiach ◽  
Arnon Wiznitzer ◽  
Marek Glezerman ◽  
...  

2009 ◽  
Vol 24 (7) ◽  
pp. 846-851 ◽  
Author(s):  
Aviva Fattal-Valevski ◽  
Hagit Toledano-Alhadef ◽  
Yael Leitner ◽  
Ronny Geva ◽  
Rina Eshel ◽  
...  

2005 ◽  
Vol 17 (5) ◽  
pp. 497 ◽  
Author(s):  
Víctor H. Parraguez ◽  
Miljenko Atlagich ◽  
Rodrigo Díaz ◽  
María E. Bruzzone ◽  
Claus Behn ◽  
...  

The present studies assessed the effect of hypobaric hypoxia on fetal lamb growth in high-altitude (HA) and low-altitude (LA) native ewes. Growth patterns of fetal biparietal diameter (BPD), abdominal diameter (AD) and thorax height (TH) were described by consecutive ultrasound measurements throughout the entire pregnancy. Three groups of animals were used: (1) pregnant LA ewes kept at LA (control; ‘LL’ group); (2) pregnant LA ewes moved to HA immediately after confirmation of pregnancy (‘LH’ group); and (3) pregnant HA ewes kept at HA throughout the entire pregnancy (‘HH’ group). The slope of the BPD curve was higher in LL fetuses followed by that in LH fetuses. During the last month of pregnancy, TH was higher in LH and HH fetuses, whereas AD was higher in LL than in LH fetuses. The length of gestation was longer in HH ewes (153.2 ± 4.3 days) than in LH and LL ewes (146.0 ± 5.5 and 145.0 ± 3.0 days, respectively). Bodyweight at birth was higher for LL newborns (4.2 ± 0.3 kg) than for LH and HH newborns (3.0 ± 0.5 and 3.2 ± 0.8 kg, respectively), whereas placental weight was higher in the HH group (396 ± 80 g) than in the LH (303 ± 64 g) and LL (280 ± 40 g) groups. In conclusion, an HA environment modifies fetal growth and pregnancy outcome with the magnitude of effects depending on the time of residence at HA.


2004 ◽  
Vol 43 (154) ◽  
Author(s):  
Pushpa Chaudhary

Intrauterine growth restriction [IUGR] is one of the leading cause of perinatal mortality and morbidity.Antenatal fetal surveillance should be focused to identify intra uterine growth restriction and intervenetimely. Screening begins with identifying pregnant women at risk of carrying growth restricted fetuses.Ultrasonic fetal biometry, amniotic fluid volume estimation and Doppler study of fetal blood flow velocityplay a valuable role in screening as well as management of IUGR. There is no promising antepartum fetaltherapy to correct IUGR. Therefore intensive fetal monitoring, which may be limited by facilities available,is suggested to time the delivery of growth restricted fetuses. Further care in a well equipped neonatal unitby dedicated team of pediatrician and nurses and appropriate follow up of these growth restricted newbornsdetermines the overall outcome.Key Words: Intrauterine growth restriction, Etiology, Screening, Diagnosis, Management.


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