scholarly journals INTRAUTERINE GROWTH RESTRICTION : AN UPDATE

2004 ◽  
Vol 43 (154) ◽  
Author(s):  
Pushpa Chaudhary
Keyword(s):  
Intrauterine Growth Restriction ◽  
Fetal Monitoring ◽  
Volume Estimation ◽  
Growth Restriction ◽  
Fetal Biometry ◽  
Intrauterine Growth ◽  
Doppler Study ◽  
Uterine Growth ◽  
Intra Uterine Growth Restriction ◽  
Dedicated Team

Intrauterine growth restriction [IUGR] is one of the leading cause of perinatal mortality and morbidity.Antenatal fetal surveillance should be focused to identify intra uterine growth restriction and intervenetimely. Screening begins with identifying pregnant women at risk of carrying growth restricted fetuses.Ultrasonic fetal biometry, amniotic fluid volume estimation and Doppler study of fetal blood flow velocityplay a valuable role in screening as well as management of IUGR. There is no promising antepartum fetaltherapy to correct IUGR. Therefore intensive fetal monitoring, which may be limited by facilities available,is suggested to time the delivery of growth restricted fetuses. Further care in a well equipped neonatal unitby dedicated team of pediatrician and nurses and appropriate follow up of these growth restricted newbornsdetermines the overall outcome.Key Words: Intrauterine growth restriction, Etiology, Screening, Diagnosis, Management.

scholarly journals An Ovarian Dermoid Cyst in Pregnancy: A Rare Cause of Intrauterine Growth Restriction

Med Phoenix ◽  
2020 ◽  
Vol 5 (1) ◽  
pp. 75-78
Author(s):  
Rubby Das ◽  
Subrina Rajbhandari
Keyword(s):  
Dermoid Cyst ◽  
Intrauterine Growth Restriction ◽  
Fetal Distress ◽  
Ovarian Tumour ◽  
Growth Restriction ◽  
Intrauterine Growth ◽  
Antenatal Period ◽  
Uterine Growth ◽  
Intra Uterine Growth Restriction ◽  
Ovarian Dermoid Cyst

The most common ovarian tumour presenting during pregnancy are dermoid cysts, usually present in the second trimester. Mostly dermoid cysts are diagnosed during ultrasound in antenatal period. We report a case of large unilateral dermoid cyst which was missed in all USG done in antenatal period but diagnosed intra-operatively while performing caesarean section for Intra uterine growth restriction (IUGR) with fetal distress. Ovarian cystectomy was done and remaining ovarian tissues were preserved. The large dermoid cyst hampered the proper growth of the fetus in utero leading to IUGR and fetal distress. Ovarian dermoid cyst in antenatal period, a rare cause of IUGR and its successful management prompted us to report this case.

scholarly journals Maternal socio-demographic determinants and fetal outcome of intrauterine growth restriction

2018 ◽  
Vol 7 (9) ◽  
pp. 3843
Author(s):  
Arpita Singh ◽  
Ambujam K.
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Maternal Risk ◽  
Intrauterine Growth ◽  
Factors Associated ◽  
Increased Risk ◽  
Uterine Growth ◽  
Intra Uterine Growth Restriction

Background: Intrauterine Growth Restriction is a major neonatal health issue. It is associated with increased risk of perinatal morbidity and mortality. Maternal factors are the major contributing factors of IUGR and studying these factors can help in preventing IUGR and reducing perinatal mortality. The objective is to study the maternal sociodemographic risk factors associated with Intra uterine growth restriction.Methods: This is a Case-control study conducted in the Department of Obstetrics and Gynaecology, GMC Thrissur. 115 cases of Intra Uterine Growth Restriction were compared to 115 controls. Data was collected by interviewing the mother using structured questionnaire which is pretested and by persual of antenatal records. Intra Uterine Growth Restriction is defined as occurring if the sonographic estimated fetal weight <10th percentile for that gestational age. Chi Square test was used for the analysis of data.Results: Low socio-economic status and malnutrition (BMI<18.5) were significant socio-demographic factors associated with fetal growth restriction. Mean birth weight in IUGR group was 1.8kg compared to 2.9kg in control group. Female fetuses were more commonly associated with IUGR. Intra Uterine Growth Restricted babies had lower Apgar scores (<7) and had more chances for NICU admission.Conclusions: By studying the maternal risk factors associated with Intra Uterine Growth Restriction, we could identify the high-risk group. Early predictive studies could be done in these high-risk pregnancies with focus on good antenatal care to reduce the problem of IUGR in the community.

scholarly journals CSH RNA Interference Reduces Global Nutrient Uptake and Umbilical Blood Flow Resulting in Intrauterine Growth Restriction

2021 ◽  
Vol 22 (15) ◽  
pp. 8150
Author(s):  
Amelia R. Tanner ◽  
Cameron S. Lynch ◽  
Victoria C. Kennedy ◽  
Asghar Ali ◽  
Quinton A. Winger ◽  
...  
Keyword(s):  
Blood Flow ◽  
Rna Interference ◽  
Nutrient Uptake ◽  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Intrauterine Growth ◽  
Umbilical Blood ◽  
Uterine Growth ◽  
Umbilical Blood Flow ◽  
Placental Hormone

Deficiency of the placental hormone chorionic somatomammotropin (CSH) can lead to the development of intrauterine growth restriction (IUGR). To gain insight into the physiological consequences of CSH RNA interference (RNAi), the trophectoderm of hatched blastocysts (nine days of gestational age; dGA) was infected with a lentivirus expressing either a scrambled control or CSH-specific shRNA, prior to transfer into synchronized recipient sheep. At 90 dGA, umbilical hemodynamics and fetal measurements were assessed by Doppler ultrasonography. At 120 dGA, pregnancies were fitted with vascular catheters to undergo steady-state metabolic studies with the 3H2O transplacental diffusion technique at 130 dGA. Nutrient uptake rates were determined and tissues were subsequently harvested at necropsy. CSH RNAi reduced (p ≤ 0.05) both fetal and uterine weights as well as umbilical blood flow (mL/min). This ultimately resulted in reduced (p ≤ 0.01) umbilical IGF1 concentrations, as well as reduced umbilical nutrient uptakes (p ≤ 0.05) in CSH RNAi pregnancies. CSH RNAi also reduced (p ≤ 0.05) uterine nutrient uptakes as well as uteroplacental glucose utilization. These data suggest that CSH is necessary to facilitate adequate blood flow for the uptake of oxygen, oxidative substrates, and hormones essential to support fetal and uterine growth.

P07.13: Intrauterine growth restriction: correlation between perinatal outcome and Doppler study of middle cerebral artery

2009 ◽  
Vol 34 (S1) ◽  
pp. 205-206
Author(s):  
L. Almeida Toledano ◽  
L. Pallarès Porta ◽  
L. Lopez ◽  
L. Alué Ponti ◽  
J. Sabrià ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Intrauterine Growth Restriction ◽  
Perinatal Outcome ◽  
Growth Restriction ◽  
Intrauterine Growth ◽  
Doppler Study

scholarly journals Early Uterine and Umbilical Artery Doppler Indices as Predictor for Preeclampsia and Intrauterine Growth Restriction

2021 ◽  
pp. 116-126
Author(s):  
Sara E. Khalil ◽  
Mohammed M. Elnamory ◽  
Mona K. omar ◽  
Hesham M. Eltokhy
Keyword(s):  
Gestational Age ◽  
Predictive Value ◽  
Intrauterine Growth Restriction ◽  
Umbilical Artery ◽  
Growth Restriction ◽  
Intrauterine Growth ◽  
Doppler Study ◽  
Significant Difference ◽  
Umbilical Artery Doppler ◽  
Doppler Indices

Background: Preeclampsia (PE) is a disorder that causes hypertension and proteinuria after week 20 of pregnancy. Several Uterine Artery (UtAs) Doppler characteristics have been investigated for their ability to predict PE. The purpose of this research is to look into the uterine and umbilical arterial Doppler indices in the early second trimester for the prediction of late preeclampsia or intrauterine growth restriction. Methods: This is a prospective cohort clinical study and was done at Obstetrics and Gynecology department, faculty of medicine Tanta university hospital from January 2020 till April 2021. 150 pregnant women aged from 18 to 30 years old with gestational age from 13 to 16 weeks of pregnancy. Study was done by the same observer by machine MINDRAY DC60 Measurement of fetal biometry (BPD, FL, AC, HC) Gestational age was confirmed with Detection of congenital malformation.    Results: There is a significant difference between the groups regarding uterine and umbilical artery doppler Indices. Uterine RI only yielded significance for predicting IUGR with sensitivity of 62% and specificity of 88%, with Positive predictive value (PPV) 37% and Negative predictive value (NPV) 92%. Umbilical resistance index achieved sensitivity of 56% and specificity of 82%, with PPV 31% and NPV 30% with on statistical significance. Conclusions: Combination of uterine and umbilical artery Doppler study in early pregnancy is one of the best indicator for prediction of preeclampsia and IUGR. Therefore, Doppler study may be used for the prediction of preeclampsia and IUGR to reduce the maternal and perinatal morbidity and mortality.

scholarly journals DOPPLER STUDY OF THE UTERINE AND UMBILICALARTERY TO PREDICT INTRAUTERINE GROWTH RETARDATION

2020 ◽  
pp. 8-10
Author(s):  
Rabiya Baseri Nelofar ◽  
Sushma Vuyyuru ◽  
Sri Hari Raavi ◽  
Nandam Hema Mohana Lakshmi
Keyword(s):  
Predictive Value ◽  
Intrauterine Growth Restriction ◽  
Uterine Artery ◽  
Umbilical Artery ◽  
Perinatal Outcomes ◽  
Indirect Evidence ◽  
Growth Restriction ◽  
Doppler Imaging ◽  
Intrauterine Growth ◽  
Doppler Study

The primary objective of this study is to transvalue the role of colour doppler sonography in the evaluation of pregnancy with intrauterine growth restriction. The study included 50 antenatal women with singleton pregnancy diagnosed as having a fetus with intrauterine growth restriction based on greyscale ultrasound findings. Further, an obstetric Doppler Ultrasound was done, and diagnostic statistics were applied to determine the Umbilical artery PI, RI, and Uterine artery PI, RI and correlating with perinatal outcomes. The specificity, sensitivity, positive predictive value, negative predictive value, and diagnostic accuracy were determined for all Doppler measurements. Among women with an identifiable cause, 42% had pregnancy-induced hypertension (PIH), 40% had moderate to severe anaemia complicating pregnancy. At the same time, 20% of the study group had no detectable cause for IUGR. The persistence of early diastolic notch beyond 26 weeks showed 60% sensitivity as a predictor for the perinatal outcome. The sensitivity of RI, PI of the uterine artery in predicting perinatal outcomes was 73 % and 76.7 %, respectively. Whereas, the sensitivity of RI, PI of the Umbilical artery in predicting perinatal outcomes was 63% and 70%, respectively. Doppler imaging provides indirect evidence of fetal compromise and is known to improve outcomes of high-risk pregnancies with intrauterine growth restriction. Hence, it is of eminent value for monitoring during the pregnancy.

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