P01.23: Combined ultrasound and biochemical screening of fetal chromosomal disorders in the first trimester of pregnancy in Russia

2006 ◽  
Vol 28 (4) ◽  
pp. 517-518
Author(s):  
A. L. Koroteev ◽  
E. S. Nekrasova ◽  
Yu. A. Nikolaeva ◽  
T. K. Kascheeva ◽  
T. V. Kuznetsova ◽  
...  
Keyword(s):  
First Trimester ◽  
Biochemical Screening ◽  
Chromosomal Disorders ◽  
First Trimester Of Pregnancy

Biochemical screening for Down’s syndrome in the first trimester of pregnancy

1993 ◽  
Vol 5 (4) ◽  
pp. 181-190 ◽  
Author(s):  
MCM Macintosh ◽  
T Chard
Keyword(s):  
Mental Retardation ◽  
Older Women ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
First Trimester ◽  
Population Screening ◽  
Severe Mental Retardation ◽  
Biochemical Screening ◽  
First Trimester Of Pregnancy

Down’s syndrome (DS) is the commonest single cause of severe mental retardation and accounts for just under a third of all cases. Until the late 1980’s population screening was based on offering amniocentensis to older women. This made little impact on the prevalence of DS because the majority (approximately 70%) of babies with DS are born to women under the age of 35 (Figure 1).

scholarly journals A Cytogenetic Study of Chromosomal Abnormalities in first trimester abortions in different maternal age groups

2017 ◽  
Vol 06 (03) ◽  
pp. 179-183
Author(s):  
Shahin Kazi ◽  
Harsha A. Keche ◽  
Keyword(s):  
Cytogenetic Analysis ◽  
Maternal Age ◽  
Chromosomal Abnormalities ◽  
Cytogenetic Study ◽  
Age Groups ◽  
First Trimester ◽  
Standard Protocol ◽  
Spontaneous Abortions ◽  
Chromosomal Disorders ◽  
First Trimester Of Pregnancy

Abstract Background : Approximately 15% of all clinically recognized pregnancies end in spontaneous abortions. Chromosomal disorders are responsible for 50% of the spontaneous abortions. Most commonly it occurs in the first trimester of pregnancy. Aim : To study the cytogenetic analysis of chorion villous tissue in 50 cases of abortion in age groups of 19-40 years. Material and Methods : Cytogenetic analysis was performed by implementing standard protocol of planting, harvesting, banding and screening. The karyotypes were prepared and observed under microscope. Statistical analysis was done by calculating the percentage of abnormal abortions in relation to maternal age. Results : It was observed that maximum abortion took place between 25-34 years of maternal age. The rate of abortion with trisomy was maximum followed by polyploidy and monosomy. It was seen that rate of abortion with monosomy decreases with increase in maternal age. Contrary to this trisomy increased with increase in maternal age. Conclusion : Cytogenetic study revealed that the rate of trisomie abortions increased with the increase in maternal age.

FRACTIONAL DETERMINATIONS OF URINARY 17-KETOSTEROIDS IN HYPEREMESIS GRAVIDARUM

1962 ◽  
Vol 41 (1) ◽  
pp. 123-128 ◽  
Author(s):  
Pentti A. Järvinen ◽  
Sykkö Pesonen ◽  
Pirkko Väänänen
Keyword(s):  
Hyperemesis Gravidarum ◽  
First Trimester ◽  
Control Group ◽  
Before And After ◽  
Daily Urine ◽  
First Trimester Of Pregnancy ◽  
The Difference

ABSTRACT The fractional determination of 17-ketosteroids in the daily urine was performed in nine cases of hyperemesis gravidarum and in four control cases, in the first trimester of pregnancy both before and after corticotrophin administration. The excretion of total 17-KS is similar in the two groups. Only in the hyperemesis group does the excretion of total 17-KS increase significantly after corticotrophin administration. The fractional determination reveals no difference between the two groups of patients with regard to the values of the fractions U (unidentified 17-KS), A (androsterone) and Rest (11-oxygenated 17-KS). The excretion of dehydroepiandrosterone is significantly higher in the hyperemesis group than in the control group. The excretion of androstanolone seems to be lower in the hyperemesis group than in the control group, but the difference is not statistically significant. The differences in the correlation between dehydroepiandrosterone and androstanolone in the two groups is significant. The high excretion of dehydroepiandrosterone and low excretion of androstanolone in cases of hyperemesis gravidarum is a sign of adrenal dysfunction.

Impact of TSH during the first trimester of pregnancy in obstetric and fetal complications: Usefulness of 2.5 mIU/l cut-off value

2018 ◽  
Author(s):  
Berta Soldevila ◽  
Marta Hernandez ◽  
Carolina Lopez ◽  
Laura Cacenarro ◽  
Maria Martinez-Barahona ◽  
...  
Keyword(s):  
First Trimester ◽  
Fetal Complications ◽  
First Trimester Of Pregnancy

Relationship between TSH values in the first trimester of pregnancy and obstetric and neonatal complications

2018 ◽  
Author(s):  
Beatriz Torres Moreno ◽  
Gabriela Castillo Carvajal ◽  
Lucrecia Vegara Fernandez ◽  
del Val Teresa Lopez ◽  
Victoria Alcazar Lazaro ◽  
...  
Keyword(s):  
First Trimester ◽  
Neonatal Complications ◽  
First Trimester Of Pregnancy
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