scholarly journals P01.02: Metabolomics fingerprint of chorionic villi in physiological state and chromosomal disorders during the first trimester of pregnancy

2019 ◽  
Vol 54 (S1) ◽  
pp. 155-155
Author(s):  
A. Iuculano ◽  
C. Peddes ◽  
V. Corda ◽  
F. Murgia ◽  
G. Monni
Keyword(s):  
Physiological State ◽  
First Trimester ◽  
Chromosomal Disorders ◽  
Chorionic Villi ◽  
First Trimester Of Pregnancy

P01.23: Combined ultrasound and biochemical screening of fetal chromosomal disorders in the first trimester of pregnancy in Russia

2006 ◽  
Vol 28 (4) ◽  
pp. 517-518
Author(s):  
A. L. Koroteev ◽  
E. S. Nekrasova ◽  
Yu. A. Nikolaeva ◽  
T. K. Kascheeva ◽  
T. V. Kuznetsova ◽  
...  
Keyword(s):  
First Trimester ◽  
Biochemical Screening ◽  
Chromosomal Disorders ◽  
First Trimester Of Pregnancy

Efficient direct chromosome analyses and enzyme determinations from chorionic villi samples in the first trimester of pregnancy

1983 ◽  
Vol 63 (4) ◽  
pp. 349-357 ◽  
Author(s):  
G. Simoni ◽  
B. Brambati ◽  
C. Danesino ◽  
F. Rossella ◽  
G. L. Terzoli ◽  
...  
Keyword(s):  
First Trimester ◽  
Chorionic Villi ◽  
First Trimester Of Pregnancy

scholarly journals Method of sampling chorionic villi in first trimester of pregnancy under guidance of real time ultrasound.

BMJ ◽  
1983 ◽  
Vol 286 (6377) ◽  
pp. 1542-1544 ◽  
Author(s):  
R H Ward ◽  
B Modell ◽  
M Petrou ◽  
F Karagozlu ◽  
E Douratsos
Keyword(s):  
Real Time ◽  
First Trimester ◽  
Chorionic Villi ◽  
First Trimester Of Pregnancy

scholarly journals INVESTIGATION OF TROPHOBLAST IN TORCH INFECTION ON ABORTION MATERIAL IN THE FIRST TRIMESTER OF PREGNANCY

2019 ◽  
Vol 18 (4) ◽  
pp. 58-62
Author(s):  
A. V. Goshovskaya ◽  
V. M. Goshovsky ◽  
S. M. Yasnikovska
Keyword(s):  
Gestational Age ◽  
Imaging System ◽  
Chorionic Villus ◽  
First Trimester ◽  
Control Group ◽  
Chorionic Villi ◽  
Infectious Process ◽  
First Trimester Of Pregnancy ◽  
Torch Infection ◽  
Immunohistochemical Studies

This study is a fragment of a series of immunohistochemical studies of trophoblast with TORCH infection, which are scheduled to be carried out at different gestational dates. This article deals with the results of trophoblast studies at the gestational age of 7-8 weeks. The study examined abortion material 7-8 weeks of gestation. The main group of the study consisted of 18 observations of TORCH infection, and the control group consisted of 17 observations of an aborted pregnancy without signs of an infectious process (abortion for social reasons). An immunohistochemical procedure was performed on metalloproteinases-2 with primary antibodies and polymer antigen imaging system using DAKO diaminobenzidine. The method of computer microdensitometry in a specialized computer program ImageJ evaluated the optical density of the color. According to the results of immunohistochemical studies using computer microdensitometry at the gestational age of 7-8 weeks, both with TORCH infection and without it an infectious process, strong expression of metalloproteinase-2 is observed in the invasive trophoblast, the smallest – in the syncytotrophoblast of the chorionic villi, and intermediate values are noted in chorionic villus cytotrophoblast and cell column cytotrophoblast. With TORCH infection the expression of metalloproteinase-2 decreases in all the four types of trophoblast (cytotrophoblast of chorionic villi; cytotrophoblast of cell columns; invasive cytotrophoblast in endometrial fragments), except for syncytotrophoblast of chorionic villi was found.

scholarly journals Uterine Glands Provide Histiotrophic Nutrition for the Human Fetus during the First Trimester of Pregnancy

2002 ◽  
Vol 87 (6) ◽  
pp. 2954-2959 ◽  
Author(s):  
Graham J. Burton ◽  
Adrian L. Watson ◽  
Joanne Hempstock ◽  
Jeremy N. Skepper ◽  
Eric Jauniaux
Keyword(s):  
First Trimester ◽  
Maternal Blood ◽  
Yolk Sac ◽  
Chorionic Villi ◽  
Intervillous Space ◽  
Human Blastocyst ◽  
Fetal Nutrition ◽  
First Trimester Of Pregnancy ◽  
Uterine Glands ◽  
Phagocytic Uptake

Providing adequate nutrition to the fetus is key to a successful pregnancy. The interstitial form of implantation displayed by the human blastocyst is generally associated with early onset of maternal blood flow to the developing placenta, and hence hemotrophic exchange. However, the recent finding that the maternal intraplacental circulation is not fully established until the third month of gestation suggests that human fetal nutrition may be initially histiotrophic. We therefore investigated activity of the uterine glands during early pregnancy. We demonstrate here that these glands remain active until at least wk 10 of pregnancy, and that their secretions are delivered freely into the placental intervillous space. We also demonstrate phagocytic uptake by the placental syncytiotrophoblast of two glycoproteins, the mucin MUC-1 and glycodelin A, synthesized in the maternal glands. Glycodelin was also detected within the epithelium of the secondary yolk sac lining the exocoelomic cavity, indicating that the yolk sac may play an important role in nutrient exchange before vascularisation of the chorionic villi. Our findings demonstrate that the uterine glands are an important source of nutrients during organogenesis, when metabolism is essentially anaerobic.

scholarly journals Peculiarity of mitotic activity of chorionic villi cytotrofoblast on the first trimester of pregnancy

2012 ◽  
Vol 61 (3) ◽  
pp. 115-122
Author(s):  
Irina Leonidovna Trofimova ◽  
Eva Valer’evna Evdokimenko ◽  
Tatyana Vladimirovna Kuznetzova
Keyword(s):  
Mitotic Activity ◽  
Proliferative Activity ◽  
First Trimester ◽  
Pericentric Heterochromatin ◽  
Missed Abortion ◽  
Chorionic Villi ◽  
First Trimester Of Pregnancy

Mitotic activity of chorionic villi cytotrophoblast of the 1st trimester at normal and missed pregnancy was studied. Proliferative activity of cytotrophoblast from missed abortions was somewhat increased in vitro. Application of a semidirect method of chromosomal preparation from chorionic villi is more efficient and provides better resolution for cytogenetic diagnostics of missed abortion. Unusual peculiarity in organization and replication of pericentric heterochromatin regions of chromosomes 1, 9 and 16 was detected

Sign in / Sign up

Export Citation Format

Share Document