Polyvinylidene fluoride/Silk fibroin‐based bio‐piezoelectric nanofibrous scaffolds for biomedical application

Author(s):  
Jeong Chan Lee ◽  
Il Won Suh ◽  
Chan Hee Park ◽  
Cheol Sang Kim
2016 ◽  
Vol 12 ◽  
pp. 42-50 ◽  
Author(s):  
N. Manikandan ◽  
S. Muruganand ◽  
K. Sriram ◽  
P. Balakrishnan ◽  
A. Suresh Kumar

The polyvinylidene fluoride (PVDF) nanofiber has widely investigated as a sensor and transducer material, because of its high piezo and Ferro electric properties. The novel nano structure of PVDF has attracted considerable interest in the bio sensing and biomedical application. This paper deals with PVDF Tactile sensor. Basically The PVDF acts as piezoelectric effect which convert load into electrical signals. The tactile sensor has a main role for visual handicap and robotics. Any physical activities of robotic in all industrial the tactile sensor is a crucible role, whether it can left the object or handling glass parts pressure of object is main. The Sandwich type PVDF base tactile sensor has been fabricated using nanofiber. Using electro spinning method, the PVDF based nanofiber coated over coper the electrodes. In normal, the PVDF has α-phase and while applying electric pulse the PVDF polymer would be changed from α-phase into β-phase. Only in β-phase, the PVDF act as piezo electrics sensor and measure the piezoelectricity simultaneously measure pressure and temperature in real time. The pressure was monitored from the change in the electrical resistance via the piezo resistance of the material. The enhancement of PVDF properties has been carried by using SEM. The SEM image result showed that the size of nanofiber, the size of nanofiber is varied in the range of (180 nm-400 nm) with smooth surface. The X-Ray diffraction has shown that the PVDF was aggregated with the β-phase crystalline nature. Due to β-phase it was act as a piezo electric prosperity’s and its results are very high sensitivity.


2013 ◽  
Vol 721 ◽  
pp. 274-277
Author(s):  
Li Li Ji ◽  
Qiao Ling Li ◽  
Zeng Hu Yang ◽  
Wei Jing Hu ◽  
Kui Hua Zhang

Vitamin E d-alpha-tocopheryl polyethylene glycol 1000 succinate (VE TPGS) loaded silk fibroin (SF)/ hyaluronic acid (HA) nanofibrous scaffolds were fabricated by means of electrospinning to biomimic the natural extracellular matrix. Scanning electronic microscopy (SEM) results indicated that electrospun VE TPGS loaded SF/HA nanofibers were ribbon-shaped, the width of nanofibers decreased slightly with the addition of VE TPGS to SF/HA blended solutions. Fourier transform infrared (FTIR) spectroscopy and Wide-angle X-ray diffraction (WAXD) curves revealed that VE TPGS did not induce SF conformation from random coil to β-sheet. SF conformation converted from random coil to β-sheet after being treated with 75% ethanol vapor. In vitro release studies confirmed VE TPGS had no obvious burst release and present good release behavior.


2010 ◽  
Vol 95A (3) ◽  
pp. 870-881 ◽  
Author(s):  
Kuihua Zhang ◽  
Yongfang Qian ◽  
Hongsheng Wang ◽  
Linpeng Fan ◽  
Chen Huang ◽  
...  

2018 ◽  
Vol 135 (37) ◽  
pp. 46684 ◽  
Author(s):  
Alireza Khosravi ◽  
Laleh Ghasemi-Mobarakeh ◽  
Hossein Mollahosseini ◽  
Fatemeh Ajalloueian ◽  
Maryam Masoudi Rad ◽  
...  

2019 ◽  
Vol 136 (28) ◽  
pp. 47730 ◽  
Author(s):  
Zexin Zheng ◽  
Kuihua Zhang ◽  
Bo Wu ◽  
Haoyi Yang ◽  
Mengqi Wang ◽  
...  

2008 ◽  
Vol 396-398 ◽  
pp. 187-190 ◽  
Author(s):  
Raquel Farias Weska ◽  
Grínia M. Nogueira ◽  
Wellington C. Vieira ◽  
Marisa Masumi Beppu

The requirements for scaffolds for bone tissue engineering include appropriate chemistry, morphology and structure to promote cell adhesion and synthesis of new bone matrix. Silk fibroin (SF) represents an important biomaterial for biomedical application, due to its suitable mechanical properties, biodegradability, biocompatibility, and versatility in processing. Our group has developed a new method to obtain a porous SF membrane, and the study of its potential for use as a scaffold for bone regeneration was the aim of this study. Porous membranes were obtained from SF solution, through the compression of a material generated by phase separation. For in vitro calcification experiments, porous SF membrane samples were immersed in SBF at pH 7.4 placed in polyethylene flasks. The experiments were carried out for seven days, at 36.5±0.5 °C. After 48 and 96h, the solutions were changed for fresh SBF with the ion concentration 1.5-fold higher than that of the standard one, to accelerate the calcification process. The characterization of morphology and composition of samples was performed by using scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS), respectively. The SEM micrographs indicated that the porous SF membranes presented calcium phosphate deposits after undergoing in vitro calcification. These results were confirmed by EDS spectra, which showed a stoichiometric molar Ca/P ratio ranging from 1.27 to 1.52. This fact may suggest that calcification deposits consisted of mixtures of HAP (Ca/P ratio = 1.67) and transient HAP precursor phases, such as octacalcium phosphate (Ca/P = 1.33) and dicalcium phosphate dehydrate (Ca/P = 1), indicating early stage mineralization. The porous silk fibroin membrane analysed in the current study is a promising material to be used as scaffolds for bone regeneration.


2014 ◽  
Vol 55 (4) ◽  
pp. 907-916 ◽  
Author(s):  
Caihong Lei ◽  
Hailin Zhu ◽  
Jingjing Li ◽  
Jiuming Li ◽  
Xinxing Feng ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (23) ◽  
pp. 19463-19474 ◽  
Author(s):  
Xili Ding ◽  
Chengqi Wu ◽  
Tong Ha ◽  
Lizhen Wang ◽  
Yan Huang ◽  
...  

A simple, one-step technology is developed to generate a hydroxyapatite (HA)-containing silk fibroin nanofibrous scaffold which has great potential as osteogenesis promoting scaffolds for constructing tissue-engineered periosteum.


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