Mechanical stretch promotes antioxidant responses and cardiomyogenic differentiation in P19 cells

2021 ◽  
Author(s):  
Jin Cheng ◽  
Qing Zou ◽  
Yugang Xue ◽  
Chuang Sun ◽  
Dongwei Zhang
Keyword(s):  
Mechanical Stretch ◽  
P19 Cells ◽  
Antioxidant Responses ◽  
Cardiomyogenic Differentiation

Alpha-lipoic acid enhances DMSO-induced cardiomyogenic differentiation of P19 cells

2014 ◽  
Vol 46 (9) ◽  
pp. 766-773 ◽  
Author(s):  
Xinghua Shen ◽  
Qinghui Yang ◽  
Peng Jin ◽  
Xueqi Li
Keyword(s):  
Lipoic Acid ◽  
P19 Cells ◽  
Alpha Lipoic Acid ◽  
Cardiomyogenic Differentiation

How do cardiomyocytes sense stretch? Effects of cyclic mechanical stretch on cardiomyocyte cellular organization

2014 ◽  
Vol 62 (S 01) ◽  
Author(s):  
S. Dhein ◽  
A. Schreiber ◽  
S. Steinbach ◽  
M. Kostelka ◽  
F.W. Mohr
Keyword(s):  
Mechanical Stretch ◽  
Cellular Organization

Antioxidant responses of the mussel Mytilus coruscus co-exposed to ocean acidification, hypoxia and warming

2020 ◽  
pp. 111869
Author(s):  
Fahim Ullah Khan ◽  
Hui Chen ◽  
Huaxin Gu ◽  
Ting Wang ◽  
Sam Dupont ◽  
...  
Keyword(s):  
Ocean Acidification ◽  
Antioxidant Responses ◽  
Mytilus Coruscus

Mechanical stretch upregulates connexin43 in human trabecular meshwork cells

2019 ◽  
Author(s):  
Nikoleta Tellios ◽  
Mary Feng ◽  
Nancy Chen ◽  
Hong Liu ◽  
Vasiliki Tellios ◽  
...  
Keyword(s):  
Trabecular Meshwork ◽  
Mechanical Stretch ◽  
Trabecular Meshwork Cells

Assessment of oxidative DNA damage, oxidative stress responses and histopathological alterations in gill and liver tissues of Oncorhynchus mykiss treated with linuron

2020 ◽  
pp. 096032712098420
Author(s):  
Ahmet Topal ◽  
Arzu Gergit ◽  
Mustafa Özkaraca
Keyword(s):  
Dna Damage ◽  
Stress Responses ◽  
Oxidative Dna Damage ◽  
Chloride Cells ◽  
Histopathological Changes ◽  
Sod Activity ◽  
Antioxidant Responses ◽  
Secondary Lamellae ◽  
Antioxidant Parameters ◽  
Oxidative Stress Responses

We investigated changes in 8-hydroxy-2-deoxyguanosine (8-OHdG) activity which is a product of oxidative DNA damage, histopathological changes and antioxidant responses in liver and gill tissues of rainbow trout, following a 21-day exposure to three different concentrations of linuron (30 µg/L, 120 µg/L and 240 µg/L). Our results indicated that linuron concentrations caused an increase in LPO levels of liver and gill tissues ( p < 0.05). While linuron induced both increases and decreases in GSH levels and SOD activity, CAT activity was decreased by all concentrations of linuron ( p < 0.05). The immunopositivity of 8-OHdG was detected in the hepatocytes of liver and in the epithelial and chloride cells of the secondary lamellae of the gill tissues. Our results suggested that linuron could cause oxidative DNA damage by causing an increase in 8-OHdG activity in tissues, and it induces histopathological damage and alterations in the antioxidant parameters of the tissues.

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