Novel fabrication method for long silicon microneedles with three-dimensional sharp tips and complicated shank shapes by isotropic dry etching

2007 ◽  
Vol 2 (3) ◽  
pp. xxiii-xxiv ◽  
Author(s):  
Hayato Izumi ◽  
Seiji Aoyagi
Keyword(s):  
Three Dimensional ◽  
Dry Etching ◽  
Fabrication Method

Realization of Three-Dimensional Nanostructure Fabrication by Nanoimprint on Silicon Substrate

2011 ◽  
Vol 211-212 ◽  
pp. 1105-1109
Author(s):  
Xi Qiu Fan
Keyword(s):  
Silicon Substrate ◽  
Low Cost ◽  
Three Dimensional ◽  
Microlens Array ◽  
Optical Lithography ◽  
High Fidelity ◽  
Fabrication Method ◽  
Nanostructure Fabrication ◽  
Large Area ◽  
3D Nanostructures

Traditional optical lithography techniques to fabricate three-dimensional (3D) nanostructures are complicated and time consuming. Due to the capability to replicate nanostructures repeatedly in a large area with high resolution and uniformity, nanoimprint (NI) has been recognized as one of the promising approaches to fabricate 3-D nanostructures with high throughput and low cost. This paper introduces a novel 3-D nanostructure fabrication method by nanoimprint on silicon substrate. Nanoscale gratings and microlens array are taken as examples of 3-D nanostructures fabricated by nanoimprint. High fidelity demonstrates the possibility of nanoimprint to fabricate 3-D nanostructures on silicon substrate.

scholarly journals 3D Printed Microfluidics

2020 ◽  
Vol 13 (1) ◽  
pp. 45-65 ◽  
Author(s):  
Anna V. Nielsen ◽  
Michael J. Beauchamp ◽  
Gregory P. Nordin ◽  
Adam T. Woolley
Keyword(s):  
3D Printing ◽  
Early Stage ◽  
Three Dimensional ◽  
Microfluidic Devices ◽  
Fabrication Method ◽  
Size Scale ◽  
Additional Work ◽  
Fluidic Devices ◽  
3D Printed ◽  
Microfabrication Techniques

Traditional microfabrication techniques suffer from several disadvantages, including the inability to create truly three-dimensional (3D) architectures, expensive and time-consuming processes when changing device designs, and difficulty in transitioning from prototyping fabrication to bulk manufacturing. 3D printing is an emerging technique that could overcome these disadvantages. While most 3D printed fluidic devices and features to date have been on the millifluidic size scale, some truly microfluidic devices have been shown. Currently, stereolithography is the most promising approach for routine creation of microfluidic structures, but several approaches under development also have potential. Microfluidic 3D printing is still in an early stage, similar to where polydimethylsiloxane was two decades ago. With additional work to advance printer hardware and software control, expand and improve resin and printing material selections, and realize additional applications for 3D printed devices, we foresee 3D printing becoming the dominant microfluidic fabrication method.

scholarly journals Advancing fabrication and properties of three-dimensional graphene–alginate scaffolds for application in neural tissue engineering

RSC Advances ◽  
2019 ◽  
Vol 9 (63) ◽  
pp. 36838-36848
Author(s):  
Negar Mansouri ◽  
Said F. Al-Sarawi ◽  
Jagan Mazumdar ◽  
Dusan Losic
Keyword(s):  
Tissue Engineering ◽  
Three Dimensional ◽  
Neural Tissue ◽  
Fabrication Method ◽  
Neural Tissue Engineering ◽  
Composite Scaffolds ◽  
3D Graphene

In this study, a bio-fabrication method has been developed for the preparation of 3D graphene–alginate composite scaffolds with great potential for neural tissue engineering.

scholarly journals Fabrication of Microneedle from Stretched Biodegradable Polymer Sheet by 3D Laser Machining

2020 ◽  
Vol 32 (2) ◽  
pp. 390-400
Author(s):  
Seiji Aoyagi ◽  
Junya Sato ◽  
Tomokazu Takahashi ◽  
Masato Suzuki ◽  
Shinichi Matsumoto ◽  
...  
Keyword(s):  
Injection Molding ◽  
Femtosecond Laser ◽  
Polylactic Acid ◽  
Biodegradable Polymer ◽  
Test Piece ◽  
Three Dimensional ◽  
Artificial Skin ◽  
Laser Machining ◽  
Resistance Force ◽  
Fabrication Method

Polylactic acid (PLA) microneedles have been usually fabricated by injection molding. Herein, we consider microneedles that mimic the maxillae of mosquito proboscises, which have sharp tips with jagged harpoon-like protrusions. In case of such microneedles, filling the melting PLA resin up to the tip of the mold trough without burrs is challenging. To address this issue, we have proposed a new microneedle fabrication method in this paper. In this method, the needle with the desired shape was obtained from a PLA sheet by femtosecond laser machining. The needle was turned by 90°, and its tip further cut obliquely with the laser for three-dimensional (3D) sharpening. Tensile and buckling tests were conducted by using a test piece cut out from the PLA sheet. It was experimentally established that the strength and Young’s modulus along the sheet’s stretch direction are higher than those along its perpendicular direction. The 3D sharpened PLA microneedle successfully penetrated an artificial skin made of polydimethylsiloxane. A pair of microneedles were alternately vibrated against each other, mimicking the motion of mosquito two maxillae. With this alternate vibration, the resistance force during insertion was found to be lower compared to that without vibration.

Examining the viability of carbon fiber reinforced three-dimensionally printed prosthetic feet created by composite filament fabrication

2018 ◽  
Vol 42 (6) ◽  
pp. 644-651 ◽  
Author(s):  
Henry H Warder ◽  
Joseph K Fairley ◽  
Joshua Coutts ◽  
Richard R Glisson ◽  
Ken Gall
Keyword(s):  
Carbon Fiber ◽  
Low Cost ◽  
Three Dimensional ◽  
Fabrication Method ◽  
Three Dimensional Printing ◽  
Energy Profiles ◽  
Prosthetic Feet ◽  
End Use ◽  
Composite Filament ◽  
Dimensional Printing

Background: A low-cost, yet high-functioning, fabrication method for prosthetic components is needed to provide underserved amputee communities with quality mobility devices. Three-dimensional printing is a potential alternative, yet limitations in material characteristics have previously prevented the technology from emerging as a solution. Objective: To validate the application of a novel three-dimensional printing technique as a fabrication method for creating fiber composite patient end-use prosthetic feet. Study design: Experimental designs were iterated upon throughout mechanical testing. Methods: A testing apparatus capable of loading prosthetic feet in dorsiflexion and plantarflexion was constructed. Load displacement data were gathered, and energy analyses were conducted. The three-dimensionally printed feet were compared to a Freedom Innovations Renegade® MX carbon fiber foot and a solid-ankle cushion heel foot. Results: The three-dimensionally printed feet achieved energy profiles that were similar, and in some cases preferable, to the energy profiles of the Renegade MX and solid-ankle cushion heel foot. The stiffness profiles of the three-dimensionally printed feet varied widely and depended greatly on the design of the feet, as well as the amount and location of the fiber reinforcement. Conclusion: Composite filament fabrication three-dimensional printing has the potential to serve as a fabrication method for the production of energy returning prosthetic feet. Clinical relevance: The results of this study indicate that carbon fiber reinforced three-dimensionally printed prosthetic feet have the potential to serve as a low-cost alternative to carbon fiber prosthetic feet and that three-dimensional printing has the capacity to function as a viable fabrication method for patient end-use prosthetic components.

Fabrication of Articulated Microarm for Endoscopy by Stacked Microassembly Process (STAMP)

2009 ◽  
Vol 21 (3) ◽  
pp. 412-418
Author(s):  
Keisuke Narumi ◽  
◽  
Daisaku Azuma ◽  
Fumihito Arai
Keyword(s):  
Image Processing ◽  
Strain Gauge ◽  
Three Dimensional ◽  
Dimensional Structure ◽  
Two Dimensional ◽  
Fabrication Method ◽  
Feedback Control System ◽  
Angle Sensor ◽  
Three Dimensional Structure ◽  
Processing Program

Recently it is expected to develop endoscopic tools to grip and lift a target tumor in Endoscopic Submucosal Dissection (ESD). We proposed a new ESD surgery concept in which two wire-driven microarms (1.8 × 1.8 × 22 mm) from the tip of endoscope help lift the tumor to cut. This paper emphasizes a new fabrication method of arm which is fabricated by Stacked Microassembly Process (STAMP). STAMP is a fabrication method of three-dimensional structure by stacking up two-dimensional sheet layers. Generically it is difficult to build a micro-order three-dimensional structure, but we overcame this problem by this method. The microarm was composed of five layers which were fabricated separately using photolithography and electroplating. In the end, individual layers were assembled together and fixed. The microarm used the elastic deformation of metal to bend (Cu or Phosphor Bronze). A strain gauge was attached to the elastic joint as an angle sensor. We calibrated the relation between the angle and output of the strain gauge using image processing program. As the relation was good linearity (R2= 0.9933), we constructed PID feedback control system. Finally, we fabricated a gripper which loaded into the tip of the microarm. The gripper could lift up a piece of meat (2 g).

scholarly journals Three-Dimensional Printing Based Hybrid Manufacturing of Microfluidic Devices

2015 ◽  
Vol 6 (2) ◽  
Author(s):  
Yunus Alapan ◽  
Muhammad Noman Hasan ◽  
Richang Shen ◽  
Umut A. Gurkan
Keyword(s):  
3D Printing ◽  
Microfluidic Device ◽  
High Surface ◽  
Three Dimensional ◽  
Microfluidic Devices ◽  
Single Step ◽  
Device Fabrication ◽  
Hybrid Manufacturing ◽  
Fabrication Method ◽  
Design Complexity

Microfluidic platforms offer revolutionary and practical solutions to challenging problems in biology and medicine. Even though traditional micro/nanofabrication technologies expedited the emergence of the microfluidics field, recent advances in advanced additive manufacturing hold significant potential for single-step, stand-alone microfluidic device fabrication. One such technology, which holds a significant promise for next generation microsystem fabrication is three-dimensional (3D) printing. Presently, building 3D printed stand-alone microfluidic devices with fully embedded microchannels for applications in biology and medicine has the following challenges: (i) limitations in achievable design complexity, (ii) need for a wider variety of transparent materials, (iii) limited z-resolution, (iv) absence of extremely smooth surface finish, and (v) limitations in precision fabrication of hollow and void sections with extremely high surface area to volume ratio. We developed a new way to fabricate stand-alone microfluidic devices with integrated manifolds and embedded microchannels by utilizing a 3D printing and laser micromachined lamination based hybrid manufacturing approach. In this new fabrication method, we exploit the minimized fabrication steps enabled by 3D printing, and reduced assembly complexities facilitated by laser micromachined lamination method. The new hybrid fabrication method enables key features for advanced microfluidic system architecture: (i) increased design complexity in 3D, (ii) improved control over microflow behavior in all three directions and in multiple layers, (iii) transverse multilayer flow and precisely integrated flow distribution, and (iv) enhanced transparency for high resolution imaging and analysis. Hybrid manufacturing approaches hold great potential in advancing microfluidic device fabrication in terms of standardization, fast production, and user-independent manufacturing.

A Simple Fabrication Method for Three-Dimensional Gold Nanoparticle Electrodes and Their Application to the Study of the Direct Electrochemistry of Cytochromec

2010 ◽  
Vol 22 (2) ◽  
pp. 185-190 ◽  
Author(s):  
Kenichi Murata ◽  
Kazuki Kajiya ◽  
Megumi Nukaga ◽  
Yosuke Suga ◽  
Toshiyuki Watanabe ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Direct Electrochemistry ◽  
Three Dimensional ◽  
Fabrication Method
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