scholarly journals Concise Review: A Critical Evaluation of Criteria Used to Define Salivary Gland Stem Cells

Stem Cells ◽  
2019 ◽  
Vol 37 (9) ◽  
pp. 1144-1150 ◽  
Author(s):  
Pei-Lun Weng ◽  
Marit H. Aure ◽  
Catherine E. Ovitt
Keyword(s):  
Stem Cells ◽  
Salivary Gland ◽  
Critical Evaluation ◽  
Concise Review

scholarly journals Concise Review: Salivary Gland Regeneration: Therapeutic Approaches from Stem Cells to Tissue Organoids

Stem Cells ◽  
2016 ◽  
Vol 35 (1) ◽  
pp. 97-105 ◽  
Author(s):  
Isabelle Lombaert ◽  
Mohammad M. Movahednia ◽  
Christabella Adine ◽  
Joao N. Ferreira
Keyword(s):  
Stem Cells ◽  
Salivary Gland ◽  
Therapeutic Approaches ◽  
Concise Review ◽  
Salivary Gland Regeneration

scholarly journals Concise Review: Adult Salivary Gland Stem Cells and a Potential Therapy for Xerostomia

Stem Cells ◽  
2013 ◽  
Vol 31 (4) ◽  
pp. 613-619 ◽  
Author(s):  
Sarah Pringle ◽  
Ronald Van Os ◽  
Robert P. Coppes
Keyword(s):  
Stem Cells ◽  
Salivary Gland ◽  
Concise Review

Concise Review: Managing Genotoxicity in the Therapeutic Modification of Stem Cells

Stem Cells ◽  
2011 ◽  
Vol 29 (10) ◽  
pp. 1479-1484 ◽  
Author(s):  
Christopher Baum ◽  
Ute Modlich ◽  
Gudrun Göhring ◽  
Brigitte Schlegelberger
Keyword(s):  
Stem Cells ◽  
Concise Review

scholarly journals Concise Review: Spinal Cord Injuries: How Could Adult Mesenchymal and Neural Crest Stem Cells Take Up the Challenge?

Stem Cells ◽  
2014 ◽  
Vol 32 (4) ◽  
pp. 829-843 ◽  
Author(s):  
Virginie Neirinckx ◽  
Dorothée Cantinieaux ◽  
Cécile Coste ◽  
Bernard Rogister ◽  
Rachelle Franzen ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Stem Cells ◽  
Neural Crest ◽  
Spinal Cord Injuries ◽  
Neural Crest Stem Cells ◽  
Concise Review

scholarly journals Concise Review: In Vitro Formation of Bone-Like Nodules Sheds Light on the Application of Stem Cells for Bone Regeneration

2016 ◽  
Vol 5 (11) ◽  
pp. 1587-1593 ◽  
Author(s):  
Saad Mechiche Alami ◽  
Sophie C. Gangloff ◽  
Dominique Laurent-Maquin ◽  
Yun Wang ◽  
Halima Kerdjoudj
Keyword(s):  
Stem Cells ◽  
Bone Regeneration ◽  
Concise Review

scholarly journals The evolving definition of salivary gland stem cells

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Cecilia Rocchi ◽  
Lara Barazzuol ◽  
Rob P. Coppes
Keyword(s):  
Stem Cells ◽  
Salivary Gland ◽  
Adult Stem Cell ◽  
Cell Types ◽  
Research Field ◽  
New Therapeutic Approaches ◽  
Recent Developments ◽  
Radiation Induced ◽  
Definition Of

AbstractDysfunction of the salivary gland and irreversible hyposalivation are the main side effects of radiotherapy treatment for head and neck cancer leading to a drastic decrease of the quality of life of the patients. Approaches aimed at regenerating damaged salivary glands have been proposed as means to provide long-term restoration of tissue function in the affected patients. In studies to elucidate salivary gland regenerative mechanisms, more and more evidence suggests that salivary gland stem/progenitor cell behavior, like many other adult tissues, does not follow that of the hard-wired professional stem cells of the hematopoietic system. In this review, we provide evidence showing that several cell types within the salivary gland epithelium can serve as stem/progenitor-like cells. While these cell populations seem to function mostly as lineage-restricted progenitors during homeostasis, we indicate that upon damage specific plasticity mechanisms might be activated to take part in regeneration of the tissue. In light of these insights, we provide an overview of how recent developments in the adult stem cell research field are changing our thinking of the definition of salivary gland stem cells and their potential plasticity upon damage. These new perspectives may have important implications on the development of new therapeutic approaches to rescue radiation-induced hyposalivation.

scholarly journals Similar ex vivo expansion and post-irradiation regenerative potential of juvenile and aged salivary gland stem cells

2015 ◽  
Vol 116 (3) ◽  
pp. 443-448 ◽  
Author(s):  
Martti Maimets ◽  
Reinier Bron ◽  
Gerald de Haan ◽  
Ronald van Os ◽  
Robert P. Coppes
Keyword(s):  
Stem Cells ◽  
Salivary Gland ◽  
Ex Vivo ◽  
Ex Vivo Expansion ◽  
Post Irradiation
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