scholarly journals Concise Review: Salivary Gland Regeneration: Therapeutic Approaches from Stem Cells to Tissue Organoids

Stem Cells ◽  
2016 ◽  
Vol 35 (1) ◽  
pp. 97-105 ◽  
Author(s):  
Isabelle Lombaert ◽  
Mohammad M. Movahednia ◽  
Christabella Adine ◽  
Joao N. Ferreira
Keyword(s):  
Stem Cells ◽  
Salivary Gland ◽  
Therapeutic Approaches ◽  
Concise Review ◽  
Salivary Gland Regeneration

scholarly journals Adult stem cells and tissue engineering strategies for salivary gland regeneration: a review

2014 ◽  
Vol 18 (1) ◽  
pp. 9 ◽  
Author(s):  
Chankee Yoo ◽  
Jeremy B Vines ◽  
Grant Alexander ◽  
Kyle Murdock ◽  
Patrick Hwang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Salivary Gland ◽  
Adult Stem Cells ◽  
Salivary Gland Regeneration

scholarly journals Concise Review: Adult Salivary Gland Stem Cells and a Potential Therapy for Xerostomia

Stem Cells ◽  
2013 ◽  
Vol 31 (4) ◽  
pp. 613-619 ◽  
Author(s):  
Sarah Pringle ◽  
Ronald Van Os ◽  
Robert P. Coppes
Keyword(s):  
Stem Cells ◽  
Salivary Gland ◽  
Concise Review

scholarly journals Concise Review: A Critical Evaluation of Criteria Used to Define Salivary Gland Stem Cells

Stem Cells ◽  
2019 ◽  
Vol 37 (9) ◽  
pp. 1144-1150 ◽  
Author(s):  
Pei-Lun Weng ◽  
Marit H. Aure ◽  
Catherine E. Ovitt
Keyword(s):  
Stem Cells ◽  
Salivary Gland ◽  
Critical Evaluation ◽  
Concise Review

scholarly journals Regenerating Salivary Glands in the Microenvironment of Induced Pluripotent Stem Cells

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Hitomi Ono ◽  
Aya Obana ◽  
Yu Usami ◽  
Manabu Sakai ◽  
Kanji Nohara ◽  
...  
Keyword(s):  
Stem Cells ◽  
Salivary Gland ◽  
Salivary Glands ◽  
Ips Cells ◽  
Initial Attempt ◽  
Cell Niche ◽  
Salivary Gland Regeneration ◽  
Induced Pluripotent

This report describes our initial attempt to regenerate salivary glands using induced pluripotent stem (iPS) cellsin vivoandin vitro. Glandular tissues that were similar to the adult submandibular glands (SMGs) and sublingual glands could be partially produced by the transplantation of iPS cells into mouse salivary glands. However, the tumorigenicity of iPS cells has not been resolved yet. It is well known that stem cells affect their microenvironment, known as a stem cell niche. We focused on the niche and the interaction between iPS cells and salivary gland cells in our study on salivary gland regeneration. Coculture of embryonic SMG cells and iPS cells have better-developed epithelial structures and fewer undifferentiated specific markers than monoculture of embryonic SMG cellsin vitro. These results suggest that iPS cells have a potential ability to accelerate differentiation for salivary gland development and regeneration.

Concise Review: Managing Genotoxicity in the Therapeutic Modification of Stem Cells

Stem Cells ◽  
2011 ◽  
Vol 29 (10) ◽  
pp. 1479-1484 ◽  
Author(s):  
Christopher Baum ◽  
Ute Modlich ◽  
Gudrun Göhring ◽  
Brigitte Schlegelberger
Keyword(s):  
Stem Cells ◽  
Concise Review

scholarly journals A Review of the Pathogenesis of Osteoarthritis and the Use of Intra-articular Platelet Therapy for Joint Disease in Animals and Humans

2014 ◽  
Vol 5 ◽  
pp. BTRI.S14578 ◽  
Author(s):  
Girolamo A. Ortolano ◽  
Barry Wenz
Keyword(s):  
Health Care ◽  
Stem Cells ◽  
Surgical Intervention ◽  
Domestic Animals ◽  
Medical Intervention ◽  
Joint Disease ◽  
Therapeutic Approaches ◽  
Disease Modifying ◽  
Care Costs ◽  
Clinical Problems

Osteoarthritis (OA) is the most prevalent musculoskeletal disease in humans and domestic animals. It causes significant clinical problems and substantial health care costs. In the absence of disease-modifying medical intervention, therapy is currently restricted to palliative measures prior to surgical intervention. We review the pathogenesis, as well as conservative and emerging restorative therapeutic approaches, including cytokines, stem cells, and platelets. The various methods of platelet concentrate preparations and their reported outcomes are discussed. Data collected from the use of intra-articular platelet therapy (IAPT) in dogs are reviewed, which suggest that this approach may delay or in some cases even obviate the need for surgical intervention.

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