A Sensitive Aptasensor Based on a Hemin/G‐Quadruplex‐Assisted Signal Amplification Strategy for Electrochemical Detection of Gastric Cancer Exosomes

Small ◽  
2019 ◽  
Vol 15 (19) ◽  
pp. 1900735 ◽  
Author(s):  
Rongrong Huang ◽  
Lei He ◽  
Yanyan Xia ◽  
Hongpan Xu ◽  
Chang Liu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Electrochemical Detection ◽  
Signal Amplification ◽  
G Quadruplex ◽  
Amplification Strategy

A label-free and enzyme-free signal amplification strategy for a sensitive RNase H activity assay

Nanoscale ◽  
2017 ◽  
Vol 9 (42) ◽  
pp. 16149-16153 ◽  
Author(s):  
Chang Yeol Lee ◽  
Hyowon Jang ◽  
Ki Soo Park ◽  
Hyun Gyu Park
Keyword(s):  
Signal Amplification ◽  
Rnase H ◽  
Label Free ◽  
Activity Assay ◽  
G Quadruplex ◽  
Catalytic Hairpin Assembly ◽  
Amplification Strategy

A target-triggered catalytic hairpin assembly with a G-quadruplex specific fluorescent binder, NMM, is employed to develop a novel and sensitive RNase H activity assay.

A signal cascade amplification strategy based on RT-PCR triggering of a G-quadruplex DNAzyme for a novel electrochemical detection of viable Cronobacter sakazakii

The Analyst ◽  
2020 ◽  
Vol 145 (13) ◽  
pp. 4477-4483
Author(s):  
Yuanyuan Yuan ◽  
Xianyong Wu ◽  
Zhanmin Liu ◽  
Qiqi Ning ◽  
Liqiang Fu ◽  
...  
Keyword(s):  
Electrochemical Detection ◽  
Rapid Detection ◽  
Detection Method ◽  
Cronobacter Sakazakii ◽  
Rt Pcr ◽  
Signal Cascade ◽  
G Quadruplex ◽  
Amplification Strategy ◽  
Cascade Amplification

An effective and sensitive DNAzyme method for electrochemical detection of viable Cronobacter sakazakii was designed. The detection method is based on RT-PCR and cascade amplification of ribozymes to achieve rapid detection of viable Cronobacter sakazakii.

K-junction structure mediated exponential signal amplification strategy for microRNA detection in electrochemiluminescence biosensor

The Analyst ◽  
2017 ◽  
Vol 142 (12) ◽  
pp. 2185-2190 ◽  
Author(s):  
Xue Li ◽  
Anyi Chen ◽  
Yaqin Chai ◽  
Ruo Yuan
Keyword(s):  
Signal Amplification ◽  
The Novel ◽  
Microrna Detection ◽  
G Quadruplex ◽  
Simple Protocol ◽  
Amplification Strategy ◽  
Junction Structure

Based on the novel designed K-junction structure, an economic and efficient exponential signal amplification strategy with simple protocol combining hemin/G-quadruplex, a mimetic peroxidase, as a catalyzer was proposed and utilized in an electrochemiluminescence biosensor for sensitive microRNA detection.

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