scholarly journals Drug Delivery: Drug-Loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling (Small 33/2017)

Small ◽  
2017 ◽  
Vol 13 (33) ◽  
Author(s):  
Mónica P. A. Ferreira ◽  
Sanjeev Ranjan ◽  
Sini Kinnunen ◽  
Alexandra Correia ◽  
Virpi Talman ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Multifunctional Nanoparticles ◽  
Hypertrophic Signaling ◽  
Endocardial Layer

Drug-Loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling

Small ◽  
2017 ◽  
Vol 13 (33) ◽  
pp. 1701276 ◽  
Author(s):  
Mónica P. A. Ferreira ◽  
Sanjeev Ranjan ◽  
Sini Kinnunen ◽  
Alexandra Correia ◽  
Virpi Talman ◽  
...  
Keyword(s):  
Multifunctional Nanoparticles ◽  
Hypertrophic Signaling ◽  
Endocardial Layer

Lanthanide-doped upconversion nanoparticles complexed with nano-oxide graphene used for upconversion fluorescence imaging and photothermal therapy

2018 ◽  
Vol 6 (4) ◽  
pp. 877-884 ◽  
Author(s):  
Po Li ◽  
Yue Yan ◽  
Binlong Chen ◽  
Pan Zhang ◽  
Siling Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Fluorescence Imaging ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Research Interest ◽  
Upconversion Nanoparticles ◽  
Multifunctional Nanoparticles ◽  
Nano Oxide

In recent years, multifunctional nanoparticles have attracted much research interest in various biomedical applications such as biosensors, diagnosis, and drug delivery systems.

Polymeric/Inorganic Multifunctional Nanoparticles for Simultaneous Drug Delivery and Visualization

2010 ◽  
Vol 1257 ◽  
Author(s):  
Andrea Fornara ◽  
Alberto Recalenda ◽  
Jian Qin ◽  
Abhilash Sugunan ◽  
Fei Ye ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Fluorescence Microscopy ◽  
Contrast Agents ◽  
Gold Nanorods ◽  
In Vitro Cytotoxicity ◽  
In Vivo Studies ◽  
Multifunctional Nanoparticles ◽  
Cytotoxicity Studies

AbstractNanoparticles consisting of different biocompatible materials are attracting a lot of interest in the biomedical area as useful tools for drug delivery, photo-therapy and contrast enhancement agents in MRI, fluorescence and confocal microscopy. This work mainly focuses on the synthesis of polymeric/inorganic multifunctional nanoparticles (PIMN) based on biocompatible di-block copolymer poly(L,L-lactide-co-ethylene glycol) (PLLA-PEG) via an emulsion-evaporation method. Besides containing a hydrophobic drug (Indomethacin), these polymeric nanoparticles incorporate different visualization agents such as superparamagnetic iron oxide nanoparticles (SPION) and fluorescent Quantum Dots (QDs) that are used as contrast agents for Magnetic Resonance Imaging (MRI) and fluorescence microscopy together. Gold Nanorods are also incorporated in such nanostructures to allow simultaneous visualization and photodynamic therapy. MRI studies are performed with different loading of SPION into PIMN, showing an enhancement in T2 contrast superior to commercial contrast agents. Core-shell QDs absorption and emission spectra are recorded before and after their loading into PIMN. With these polymeric/inorganic multifunctional nanoparticles, both MRI visualization and confocal fluorescence microscopy studies can be performed. Gold nanorods are also synthesized and incorporated into PIMN without changing their longitudinal absorption peak usable for lased excitation and phototherapy. In-vitro cytotoxicity studies have also been performed to confirm the low cytotoxicity of PIMN for further in-vivo studies.

Mesostructured multifunctional nanoparticles for imaging and drug delivery

2009 ◽  
Vol 19 (35) ◽  
pp. 6251 ◽  
Author(s):  
Monty Liong ◽  
Sarah Angelos ◽  
Eunshil Choi ◽  
Kaushik Patel ◽  
J. Fraser Stoddart ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Multifunctional Nanoparticles

Multifunctional nanoparticles for oral protein drug delivery

2016 ◽  
Vol 120 ◽  
pp. S19
Author(s):  
Er-Yuan Chuang ◽  
Kun-Ju Lin ◽  
Fang-Yi Su ◽  
Fwu-Long Mi ◽  
Chiung-Tong Chen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Protein Drug ◽  
Multifunctional Nanoparticles ◽  
Protein Drug Delivery

Engineered Multifunctional Nanoparticles for DLA Cancer Cells Targeting, Sorting, MR Imaging and Drug Delivery

2013 ◽  
Vol 5 (12) ◽  
pp. 1340-1348 ◽  
Author(s):  
Gunasekaran Amsaveni ◽  
Abubacker Sulaiman Farook ◽  
Viswanathan Haribabu ◽  
Ramachandran Murugesan ◽  
Agnishwar Girigoswami
Keyword(s):  
Drug Delivery ◽  
Mr Imaging ◽  
Cancer Cells ◽  
Multifunctional Nanoparticles

scholarly journals Self-assembled nanoparticles as multifunctional drugs for anti-microbial therapies

2014 ◽  
Vol 50 (57) ◽  
pp. 7649-7651 ◽  
Author(s):  
Manpreet Bhatti ◽  
Timothy D. McHugh ◽  
Lilia Milanesi ◽  
Salvador Tomas
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Multifunctional Nanoparticles ◽  
Multifunctional Drugs ◽  
Self Assembled

Multifunctional nanoparticles that kill mycobacteria: nano-Trojan horses for photodynamic therapy and anti-TB drug delivery.

Co-biomembrane coated Fe3O4/MnO2 multifunctional nanoparticles for targeted delivery and enhanced hemodynamic/photothermal/chemo therapy

2021 ◽  
Author(s):  
Yingshu Guo ◽  
Xiaofei Zheng ◽  
Tingting Gai ◽  
Zhiyong Wei ◽  
Shu-Sheng Zhang
Keyword(s):  
Breast Cancer ◽  
Escherichia Coli ◽  
Drug Delivery ◽  
Cell Membrane ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Targeted Delivery ◽  
Membrane System ◽  
Multifunctional Nanoparticles ◽  
Mcf 7

Here, the co-membrane system of MCF-7 breast cancer cell membrane (MM) and Escherichia coli membrane (EM)-coated Fe3O4/MnO2 multifunctional composite nanoparticles loaded with DOX (Fe3O4/MnO2/MM/EM/D) was used for targeting drug delivery...

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