scholarly journals Tissue Engineering: Effective Light Directed Assembly of Building Blocks with Microscale Control (Small 24/2017)

Small ◽  
2017 ◽  
Vol 13 (24) ◽  
Author(s):  
Ngoc-Duy Dinh ◽  
Rongcong Luo ◽  
Maria Tankeh Asuncion Christine ◽  
Weikang Nicholas Lin ◽  
Wei-Chuan Shih ◽  
...  
Author(s):  
Joshua D. Carter ◽  
Chenxiang Lin ◽  
Yan Liu ◽  
Hao Yan ◽  
Thomas H. LaBean

This article examines the DNA-based self-assembly of nanostructures. It first reviews the development of DNA self-assembly and DNA-directed assembly, focusing on the main strategies and building blocks available in the modern molecular construction toolbox, including the design, construction, and analysis of nanostructures composed entirely of synthetic DNA, as well as origami nanostructures formed from a mixture of synthetic and biological DNA. In particular, it considers the stepwise covalent synthesis of DNA nanomaterials, unmediated assembly of DNA nanomaterials, hierarchical assembly, nucleated assembly, and algorithmic assembly. It then discusses DNA-directed assembly of heteromaterials such as proteins and peptides, gold nanoparticles, and multicomponent nanostructures. It also describes the use of complementary DNA cohesion as 'smart glue' for bringing together covalently linked functional groups, biomolecules, and nanomaterials. Finally, it evaluates the potential future of DNA-based self-assembly for nanoscale manufacturing for applications in medicine, electronics, photonics, and materials science.


2001 ◽  
Vol 113 (15) ◽  
pp. 2993-2996 ◽  
Author(s):  
So-Jung Park ◽  
Anne A. Lazarides ◽  
Chad A. Mirkin ◽  
Robert L. Letsinger

RSC Advances ◽  
2018 ◽  
Vol 8 (28) ◽  
pp. 15675-15686 ◽  
Author(s):  
Jacquelyn G. Egan ◽  
Nicole Drossis ◽  
Iraklii I. Ebralidze ◽  
Holly M. Fruehwald ◽  
Nadia O. Laschuk ◽  
...  

The ability to form complex 3D architectures using nanoparticles as the building blocks and complex macromolecules that direct these assemblies remains a challenging objective for nanotechnology.


2019 ◽  
Vol 48 (27) ◽  
pp. 9916-9919 ◽  
Author(s):  
Qing-Rong Ding ◽  
Gui-Lan Xu ◽  
Lei Zhang ◽  
Jian Zhang

A facile approach of ligand-directed assembly of trapezoidal {Ti5} building blocks was successfully established, which gave rise to interesting hybrid clusters including the first molecular assembly of porphyrin photosensitizer and titanium-oxo cluster.


2018 ◽  
Vol 6 (3) ◽  
pp. 550-561 ◽  
Author(s):  
Koji Nagahama ◽  
Naho Oyama ◽  
Kimika Ono ◽  
Atsushi Hotta ◽  
Keiko Kawauchi ◽  
...  

Nanocomposite injectable gels, which self-replenish regenerative extracellular microenvironments within the gels in the body by utilizing host-derived bioactive molecules as building blocks, are reported.


Author(s):  
Weiguo Qiu ◽  
Joseph Cappello ◽  
Xiaoyi Wu

Micro- and submicro-diameter protein fibers are fundamental building blocks of extra- and intra-cellular matrices, providing structural support, stability and protection to cells, tissues and organism [1]. Fabricating performance fibers of both naturally derived and genetically engineered proteins has been extensively pursued for a variety of biomedical applications, including tissue engineering and drug delivery [2]. Silk-elastin-like proteins (SELPs), consisting of tandemly repeated polypeptide sequences derived from silk and elastin, have been biosynthesized using recombinant DNA technique [3]. Their potential as a biomaterials in the form of hydrogels continues to be explored [4, 5]. This study will focus on the fabrication of robust, micro-diameter SELP fibers as biomaterials for tissue engineering applications.


Author(s):  
Duarte Nuno Carvalho ◽  
Ana Rita Inácio ◽  
Rita O. Sousa ◽  
Rui L. Reis ◽  
Tiago H. Silva

2001 ◽  
Vol 13 (10) ◽  
pp. 3218-3226 ◽  
Author(s):  
Sean A. Davis ◽  
Michael Breulmann ◽  
Katja H. Rhodes ◽  
Baojian Zhang ◽  
Stephen Mann

Langmuir ◽  
2008 ◽  
Vol 24 (20) ◽  
pp. 11464-11473 ◽  
Author(s):  
L. Todd Banner ◽  
Delia C. Danila ◽  
Katie Sharpe ◽  
Melissa Durkin ◽  
Benjamin Clayton ◽  
...  

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