Highly Sensitive and Broadband Organic Photodetectors with Fast Speed Gain and Large Linear Dynamic Range at Low Forward Bias

Small ◽  
2017 ◽  
Vol 13 (24) ◽  
pp. 1603260 ◽  
Author(s):  
Riming Nie ◽  
Xianyu Deng ◽  
Lei Feng ◽  
Guiguang Hu ◽  
Yangyang Wang ◽  
...  
Keyword(s):  
Dynamic Range ◽  
Forward Bias ◽  
Linear Dynamic Range ◽  
Linear Dynamic ◽  
Fast Speed ◽  
Highly Sensitive ◽  
Organic Photodetectors

scholarly journals Development of a Quantitative Real-Time PCR Assay for Detection of Toxoplasma gondii in Brain Samples

2021 ◽  
Author(s):  
Mahboubeh Berizi ◽  
Jalal Babaie ◽  
Pezhman Fard-Esfahani ◽  
Marjan Enshaeieh ◽  
Rahmah Noordin ◽  
...  
Keyword(s):  
Detection Limit ◽  
Toxoplasma Gondii ◽  
Real Time Pcr ◽  
Genomic Dna ◽  
Dynamic Range ◽  
Quantitative Real Time Pcr ◽  
Linear Dynamic Range ◽  
Standard Curve ◽  
Linear Dynamic ◽  
Highly Sensitive

Background: Toxoplasmosis is a worldwide-distributed infection that can cause serious diseases, mainly in congenitally infected and immunodeficient individuals. PCR assays play an indispensable role in the detection of Toxoplasma gondii in different biological samples. Methods: This study was conducted in the Parasitology Department at Pasteur Institute of Iran (Tehran) during 2016-2018. We designed a highly sensitive quantitative real-time PCR (RT-qPCR) targeted REP-529, a noncoding repetitive DNA. We cloned the amplicon in a plasmid (pTZREP-529) and used it to generate the standard curve. The Toxoplasma RT-qPCR characteristics, i.e., detection limit, specificity, linear dynamic range, linearity, intra-, and inter-assay precisions, were determined. The detection limit of the assay was one plasmid copy number (PCN) per reaction (about 0.004 T. gondii genome), and the linear dynamic range was equal to 6 logs (1× 101 to 1× 107 PCN per reaction). Results: The assay showed no signal when genomic DNA of Plasmodium falciparum, Leishmania major, and Trichomonas vaginallis were used. The standard curve was drawn using dilutions of pTZREP-529 plasmid spiked with genomic DNA from a mouse brain, and test characteristics were shown unaffected. Applying the Toxoplasma RT-qPCR, we showed brain cysts were significantly decreased in mice vaccinated with GRA2 antigen of Toxoplasma formulated in Monophosphoryl Lipid A (MPL) adjuvant. Conclusion: We have developed a quantitative, specific, and highly sensitive PCR for detecting T. gondii in biological samples.

Highly sensitive all-polymer photodetectors with ultraviolet-visible to near-infrared photo-detection and its application as optical switch

2021 ◽  
Author(s):  
Zijin Zhao ◽  
Baiqiao Liu ◽  
Chunyu Xu ◽  
Ming Liu ◽  
Kaixuan Yang ◽  
...  
Keyword(s):  
External Quantum Efficiency ◽  
Near Infrared ◽  
Dynamic Range ◽  
Optical Switch ◽  
Signal To Noise Ratio ◽  
Linear Dynamic Range ◽  
Signal To Noise ◽  
Linear Dynamic ◽  
Highly Sensitive ◽  
Photo Detection

All-polymer photodetectors with photomultiplication are fabricated with PMBBDT and N2200 as photoactive layers, exhibiting external quantum efficiency of 20700% under 4 V. Signal-to-noise ratio, linear dynamic range and specific detectivity...

Convenient Fiber-Optic-Based Sample Cell for Shpol'skii and Low-Temperature Phosphorescence Spectrometry

1989 ◽  
Vol 43 (3) ◽  
pp. 422-425 ◽  
Author(s):  
Richard T. Madison ◽  
Mary K. Carroll ◽  
Gary M. Hieftje
Keyword(s):  
Low Temperature ◽  
Fiber Optic ◽  
Dynamic Range ◽  
Detection Limits ◽  
Linear Dynamic Range ◽  
Sample Cell ◽  
Linear Dynamic ◽  
Light Guides

A sample cell for observing the Shpol'skii effect at 77 K is described and analytically assessed. The cell employs fiber-optic light guides to transport excitation and emission radiation. The system is compact, inexpensive, and simple to construct from commercially available laboratory components, and it alleviates several problems inherent in conventional refrigerated-cell designs. Detection limits for anthracene, coronene, and pyrene obtained with the sample cell are 8.8 × 10−8 M, 8.4 × 10−7 M, and 3.5 × 10−7 M, respectively. The linear dynamic range for each compound is 2 to 3 orders of magnitude.

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