Aqueous‐Phased Electrospun Bioactive Glass Mineralized Gelatin‐Pectin Hybrid Composite Fiber Matrix For 7‐Dehydrocholesterol Delivery

2020 ◽  
Vol 5 (14) ◽  
pp. 4364-4370
Author(s):  
Nidhi Gupta ◽  
Himansh Goel ◽  
Deenan Santhiya ◽  
Chandra Mohan Srivastava ◽  
Sarita Mishra ◽  
...  
2016 ◽  
Vol 104 (10) ◽  
pp. 2604-2615 ◽  
Author(s):  
Venu G. Varanasi ◽  
Tetsurou Odatsu ◽  
Timothy Bishop ◽  
Joyce Chang ◽  
Jeremy Owyoung ◽  
...  

ACS Omega ◽  
2020 ◽  
Vol 5 (21) ◽  
pp. 12090-12102
Author(s):  
Amit Chatterjee ◽  
Hemavathy Nagarajan ◽  
Prema Padmanabhan ◽  
Umashankar Vetrivel ◽  
Kulandhai Lily Therese ◽  
...  

1994 ◽  
Vol 370 ◽  
Author(s):  
Gebran N. Karam

AbstractThe area and properties of the fiber-matrix interface in fiber reinforced cements and concretes determines the amount of stress transferred forth and back between the cement paste and the reinforcement and hence controls the mechanical properties of the composite. Fiber-fiber interaction and overlap of fibers with fibers, voids and aggregates can dramatically decrease the efficiency of the reinforcement by reducing this interfacial area. A simple model to account for this reduction is proposed and ways to integrate it in the models describing the mechanical properties of short fiber reinforced concretes are presented. The parameters of the model are evaluated from previously published data sets and its predictions are found to compare well with experimental observations; for example, it is able to predict the non-linear variation of bending and tensile strength with increasing fiber volume fraction as well as the existence of an optimal fiber content.


2018 ◽  
Vol 4 (1) ◽  
pp. 123-130 ◽  
Author(s):  
S. Labbaf ◽  
A. Baharlou Houreh ◽  
M. Rahimi ◽  
Hung-Kai Ting ◽  
Jr. Jones ◽  
...  

Abstract The study reports the fabrication and in vitro biological evaluation of a sol-gel derived bioactive glass (BG) / polycaprolactone (PCL) composite fiber membrane, as a potential candidate for bone regeneration applications. The non woven composite mats were prepared by introducing the glass particles into the electrospinning process. Adding the glass improved the homogeneity of the fibers. The apatite forming ability of the membranes in simulated body fluid were evaluated and showed that hydroxyapatite had formed within 21 days in SBF and completely covered the surface of the membrane. In cell culture, dental pulp stem cells adhered proliferated and produced mineralized matrix on the PCL/BG fiber membrane.


Author(s):  
Xiao Han ◽  
Yan Chen ◽  
Qian Jiang ◽  
Xin Liu ◽  
Yaming Chen

Secondary caries seriously limits the lifetime of composite resin. However, integrating all desirable properties (i.e., mechanical, antibacterial, bioactivity, and biocompatibility) into one composite resin is still challenging. Herein, a novel bioactive glass (BAG)-modified hybrid composite resin has been successfully developed to simultaneously achieve excellent mechanical properties, good biocompatibility, and antibacterial and remineralizing capabilities. When the mass fractions of BAG particles were added from 8 to 23 wt %, the original mechanical properties of the composite resin, including flexural strength and compressive strength, were not obviously affected without compromising the degree of conversion. Although the BAG incorporation of mass fractions of 16 wt % to 23 wt % in composite resins reduced cell viability, the viability could be recovered to normal by adjusting the pH value. Moreover, the BAG-modified composite resins that were obtained showed good antibacterial effects against Streptococcus mutans and enhanced remineralizing activity on demineralized dentin surfaces with increasing incorporation of BAG particles. The possible mechanisms for antibacterial and remineralizing activity might be closely related to the release of bioactive ions (Ca2+, Si4+), suggesting that its antibacterial and biological properties can be controlled by modulating the amounts of bioactive ions. The capability to balance the mechanical properties, cytotoxicity, antibacterial activity, and bioactivity makes the BAG-modified composite resin a promising prospect for clinical application. Our findings provide insight into better design and intelligent fabrication of bioactive composite resins.


2012 ◽  
Vol 498 ◽  
pp. 210-218 ◽  
Author(s):  
Bouchra Hassoune-Rhabbour ◽  
Laurence Poussines ◽  
Valérie Nassiet

There are several models on the relationship structures and properties of the composite fiber / matrix interface [1]. Including literature proposes the development of micromechanical tests suitable for assessing the shear strength of the interface fiber / polymer matrix. The first test which allowed to characterize the fiber / matrix interface is the pull-out test developed by Broutman [2]. It consists in extracting the fiber from the matrix that can be in block form, gout or disk of resin. To reduce the variation in results due to the geometries used, it was agreed to use a drop of resin with small dimensions. The test is to characterize the fiber / matrix interface of natural thermosetting or thermoplastic by determining the shear stress.


2015 ◽  
Vol 1131 ◽  
pp. 79-83 ◽  
Author(s):  
Ratiya Phetnin ◽  
Sirirat Tubsungnoen Rattanachan

This research aims to fabricate the novel bio-hybrid composite scaffold from mesoporous bioactive glasses/silk fibroin/chitosan (MBGs/SF/CS) for use in tissue engineering applications. MBGs/SF/CS composite scaffolds were successfully fabricated using freezing and lyophilization process. Two types of mesoporous bioactive glasses which were irregular and spherical shape were dispersed in the silk fibroin/chitosan based scaffolds in order to improve the mechanical strength and bioactivity. SEM observation showed the interconnected pores with pore size from 100 to 300 µm. XRD and FTIR exhibited the present of silk fibroin, chitosan, and MBGs in composite scaffolds. The incorporation of MBGs in SF/CS scaffolds significantly increased the compressive strength of scaffolds. The composite scaffolds were immersed in the simulated body fluid (SBF) for in vitro bioactivity test. The in vitro bioactivity results indicated that the MBGs/SF/CS induced hydroxycarbonate apatite (HCA) formation while there was no change for SF/CS scaffolds. Furthermore, mesoporous bioactive glass with micro-spherical particles (MBGMs) which easily dispersed in SF/CS solution during the fabrication of scaffolds as compared to mesoporous bioactive glass with irregular shape (MBGs). The results showed that MBGs/SF/CS composite scaffolds could be useful composite scaffolds for tissue engineering applications.


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