scholarly journals Enhanced osteoprogenitor elongated collagen fiber matrix formation by bioactive glass ionic silicon dependent on Sp7 (osterix) transcription

2016 ◽  
Vol 104 (10) ◽  
pp. 2604-2615 ◽  
Author(s):  
Venu G. Varanasi ◽  
Tetsurou Odatsu ◽  
Timothy Bishop ◽  
Joyce Chang ◽  
Jeremy Owyoung ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Collagen Fiber ◽  
Fiber Matrix

Continuous cyclic stretch induces osteoblast alignment and formation of anisotropic collagen fiber matrix

2013 ◽  
Vol 9 (7) ◽  
pp. 7227-7235 ◽  
Author(s):  
Aira Matsugaki ◽  
Natsuko Fujiwara ◽  
Takayoshi Nakano
Keyword(s):  
Collagen Fiber ◽  
Cyclic Stretch ◽  
Fiber Matrix

scholarly journals Ultrastructural changes in the collagen fiber matrix after thermal injury.

1999 ◽  
Vol 10 (12) ◽  
pp. 730-731
Author(s):  
Shoichiro Shimizu ◽  
Hideharu Tanaka ◽  
Shoichiro Shimizu ◽  
Shuji Shimazaki ◽  
Yoshihiro Akimoto ◽  
...  
Keyword(s):  
Collagen Fiber ◽  
Thermal Injury ◽  
Ultrastructural Changes ◽  
Fiber Matrix

The Biologic Tissue Responses to Uncoated and Coated Implanted Biomaterials

1999 ◽  
Vol 13 (1) ◽  
pp. 27-33 ◽  
Author(s):  
D.E. Steflik ◽  
R.S. Corpe ◽  
T.R. Young ◽  
A.L. Sisk ◽  
G.R. Parr
Keyword(s):  
Collagen Fiber ◽  
Bone Matrix ◽  
Titanium Implants ◽  
Osteoblastic Activity ◽  
Osseointegrated Implants ◽  
Tissue Responses ◽  
Ceramic Implants ◽  
Fiber Matrix ◽  
Morphology And Morphometry ◽  
Uncoated Titanium

Ultrastructural examination of the morphology and morphometry of the bone supporting uncoated titanium and ceramic implants was assessed in an experimental animal model involving 120 implants placed into the mandibles of 30 adult mongrel dogs. Further, preliminary morphologic and morphometric observations of the bone supporting uncoated and hydroxylapatite-coated endosteal titanium implants was evaluated in a second investigation involving 72 implants placed into the mandibles and maxillae of 6 additional dogs. A densely mineralized collagen fiber matrix was observed directly interfacing with uncoated implants. The only material interposed between the implant and bone matrix was a 20- to 50-nm electron-dense material suggestive of a proteoglycan. Also seen in these same osseointegrated implants were narrow unmineralized zones interposed between the implant and bone matrix. In these zones of remodeling bone, numerous osteoblasts were observed interacting with the collagen fiber matrix. It was shown that a normal homeostasis of anabolic osteoblastic activity and catabolic osteoclastic activity resulted in bone remodeling and the resultant osseointegration of the implants. Hydroxylapatite-coated implants intimately interfaced with healthy bone. The mineralized matrix extended into the microporosity of the HA coating. This matrix contained viable osteocytes.

scholarly journals A Coupled Fiber-Matrix Model Demonstrates Highly Inhomogeneous Microstructural Interactions in Soft Tissues Under Tensile Load

2012 ◽  
Vol 135 (1) ◽  
Author(s):  
Lijuan Zhang ◽  
Spencer P. Lake ◽  
Victor K. Lai ◽  
Catalin R. Picu ◽  
Victor H. Barocas ◽  
...  
Keyword(s):  
Stress Field ◽  
Matrix Model ◽  
Collagen Fiber ◽  
Soft Tissues ◽  
Computational Cost ◽  
Parallel Model ◽  
Fiber Network ◽  
Detailed Model ◽  
The Matrix ◽  
Fiber Matrix

A soft tissue's macroscopic behavior is largely determined by its microstructural components (often a collagen fiber network surrounded by a nonfibrillar matrix (NFM)). In the present study, a coupled fiber-matrix model was developed to fully quantify the internal stress field within such a tissue and to explore interactions between the collagen fiber network and nonfibrillar matrix (NFM). Voronoi tessellations (representing collagen networks) were embedded in a continuous three-dimensional NFM. Fibers were represented as one-dimensional nonlinear springs and the NFM, meshed via tetrahedra, was modeled as a compressible neo-Hookean solid. Multidimensional finite element modeling was employed in order to couple the two tissue components and uniaxial tension was applied to the composite representative volume element (RVE). In terms of the overall RVE response (average stress, fiber orientation, and Poisson's ratio), the coupled fiber-matrix model yielded results consistent with those obtained using a previously developed parallel model based upon superposition. The detailed stress field in the composite RVE demonstrated the high degree of inhomogeneity in NFM mechanics, which cannot be addressed by a parallel model. Distributions of maximum/minimum principal stresses in the NFM showed a transition from fiber-dominated to matrix-dominated behavior as the matrix shear modulus increased. The matrix-dominated behavior also included a shift in the fiber kinematics toward the affine limit. We conclude that if only gross averaged parameters are of interest, parallel-type models are suitable. If, however, one is concerned with phenomena, such as individual cell-fiber interactions or tissue failure that could be altered by local variations in the stress field, then the detailed model is necessary in spite of its higher computational cost.

Biodegradable porous organosilicone-modified collagen fiber matrix: Synthesis and high oil absorbency

2018 ◽  
Vol 135 (20) ◽  
pp. 46264 ◽  
Author(s):  
Weining Du ◽  
Guochen Dai ◽  
Baochuan Wang ◽  
Zhengjun Li ◽  
Lixin Li
Keyword(s):  
Collagen Fiber ◽  
Matrix Synthesis ◽  
Oil Absorbency ◽  
Fiber Matrix

Aqueous‐Phased Electrospun Bioactive Glass Mineralized Gelatin‐Pectin Hybrid Composite Fiber Matrix For 7‐Dehydrocholesterol Delivery

2020 ◽  
Vol 5 (14) ◽  
pp. 4364-4370
Author(s):  
Nidhi Gupta ◽  
Himansh Goel ◽  
Deenan Santhiya ◽  
Chandra Mohan Srivastava ◽  
Sarita Mishra ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Hybrid Composite ◽  
Composite Fiber ◽  
Fiber Matrix

Oil sorption behaviors of porous polydimethylsiloxane modified collagen fiber matrix

2015 ◽  
Vol 132 (44) ◽  
pp. n/a-n/a ◽  
Author(s):  
Weining Du ◽  
Xiaona Han ◽  
Zhengjun Li ◽  
Yupeng Li ◽  
Lixin Li ◽  
...  
Keyword(s):  
Collagen Fiber ◽  
Oil Sorption ◽  
Fiber Matrix

Techniques for Transmission Electron Microscopy of Fiber-Matrix Interfaces in Aluminum Alloy-Boron Composites by Ion Erosio

1971 ◽  
Vol 29 ◽  
pp. 204-205
Author(s):  
G. G. Shaw
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Aluminum Alloy ◽  
Electron Beam ◽  
Pure Aluminum ◽  
Ion Milling ◽  
Transmission Electron ◽  
Fiber Matrix ◽  
Ion Erosion ◽  
Row Of Fibers

The morphology and composition of the fiber-matrix interface can best be studied by transmission electron microscopy and electron diffraction. For some composites satisfactory samples can be prepared by electropolishing. For others such as aluminum alloy-boron composites ion erosion is necessary.When one wishes to examine a specimen with the electron beam perpendicular to the fiber, preparation is as follows: A 1/8 in. disk is cut from the sample with a cylindrical tool by spark machining. Thin slices, 5 mils thick, containing one row of fibers, are then, spark-machined from the disk. After spark machining, the slice is carefully polished with diamond paste until the row of fibers is exposed on each side, as shown in Figure 1.In the case where examination is desired with the electron beam parallel to the fiber, preparation is as follows: Experimental composites are usually 50 mils or less in thickness so an auxiliary holder is necessary during ion milling and for easy transfer to the electron microscope. This holder is pure aluminum sheet, 3 mils thick.

Characterization of interfaces in CVD-coated nicalon fiber-reinforced SiC

1989 ◽  
Vol 47 ◽  
pp. 556-557
Author(s):  
K.L. More ◽  
R.A. Lowden
Keyword(s):  
Mechanical Properties ◽  
Fracture Toughness ◽  
Chemical Vapor ◽  
Chemical Vapor Infiltration ◽  
Frictional Stress ◽  
Fiber Reinforced ◽  
Pull Out ◽  
Carbon Coated ◽  
Fiber Matrix

The mechanical properties of fiber-reinforced composites are directly related to the nature of the fiber-matrix bond. Fracture toughness is improved when debonding, crack deflection, and fiber pull-out occur which in turn depend on a weak interfacial bond. The interfacial characteristics of fiber-reinforced ceramics can be altered by applying thin coatings to the fibers prior to composite fabrication. In a previous study, Lowden and co-workers coated Nicalon fibers (Nippon Carbon Company) with silicon and carbon prior to chemical vapor infiltration with SiC and determined the influence of interfacial frictional stress on fracture phenomena. They found that the silicon-coated Nicalon fiber-reinforced SiC had low flexure strengths and brittle fracture whereas the composites containing carbon coated fibers exhibited improved strength and fracture toughness. In this study, coatings of boron or BN were applied to Nicalon fibers via chemical vapor deposition (CVD) and the fibers were subsequently incorporated in a SiC matrix. The fiber-matrix interfaces were characterized using transmission and scanning electron microscopy (TEM and SEM). Mechanical properties were determined and compared to those obtained for uncoated Nicalon fiber-reinforced SiC.

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