Antiinflammatory property of the leaves of Gongronema latifolium

2002 ◽  
Vol 16 (S1) ◽  
pp. 75-77 ◽  
Author(s):  
Olugbenga Morebise ◽  
Michael A. Fafunso ◽  
J. Modupe Makinde ◽  
Olumayokun A. Olajide ◽  
E.O. Awe
Keyword(s):  
Antiinflammatory Property ◽  
Gongronema Latifolium

Iloneoside: a cytotoxic ditigloylated pregnane glycoside from the leaves of Gongronema latifolium Benth

2017 ◽  
Vol 32 (24) ◽  
pp. 2882-2886 ◽  
Author(s):  
Gideon Ampoma Gyebi ◽  
Joseph Oluwatope Adebayo ◽  
Olufunke Esan Olorundare ◽  
Antoni Pardede ◽  
Masayuki Ninomiya ◽  
...  
Keyword(s):  
Pregnane Glycoside ◽  
Gongronema Latifolium

Assessment of a bioactive compound for its potential antiinflammatory property by tight junction permeability

2005 ◽  
Vol 19 (12) ◽  
pp. 1009-1012 ◽  
Author(s):  
Young Hoon Bai ◽  
Sok Cheon Pak ◽  
Seung Hoo Lee ◽  
Chun Sik Bae ◽  
Colin Prosser ◽  
...  
Keyword(s):  
Tight Junction ◽  
Bioactive Compound ◽  
Antiinflammatory Property ◽  
Tight Junction Permeability

Postweaning administration of aqueous leaf extract of Gongronema latifolium may improve obesity indices in young adult offspring

2021 ◽  
Vol 9 (3) ◽  
pp. 186
Author(s):  
Okekem Amadi ◽  
DeborahB Adeniyi ◽  
NkiruA Katchy ◽  
Vivian Nwannadi ◽  
PrincewillIkechukwu Ugwu ◽  
...  
Keyword(s):  
Young Adult ◽  
Leaf Extract ◽  
Adult Offspring ◽  
Aqueous Leaf Extract ◽  
Obesity Indices ◽  
Gongronema Latifolium

scholarly journals Co-administration of Rauwolfia vomitoria with Gongronema latifolium or Vernonia amygdalina on spatial learning, memory, and some bio-molecules

2015 ◽  
Vol 7 (1) ◽  
pp. 82-87 ◽  
Author(s):  
Moses B Ekong ◽  
Aniekan I Peter ◽  
Ubong U Ekpene
Keyword(s):  
Learning And Memory ◽  
Spatial Learning ◽  
Psychotic Disorders ◽  
Acute Effect ◽  
Tween 20 ◽  
Spatial Learning And Memory ◽  
Vernonia Amygdalina ◽  
Male Wistar Rats ◽  
Gongronema Latifolium ◽  
Rauwolfia Vomitoria

Background: Rauwolfia vomitoria is a plant with sedative properties found useful in the management of psychotic disorders, with adverse effects being reported on its use in different brain areas.Aims and Objectives: To investigate the acute effect of combination of Rauwolfia vomitoria with either Gongronema latifolium or Vernonia amygdalina on spatial learning and memory, and some bio-molecules in rats.Materials and Methods: 24 adult male Wistar rats weighing between 220 g - 300 g were equally divided into four groups (1-4). Group 1 animals were the control treated with 0.5 ml of Tween 20. Groups 2, 3 and 4 animals were administered respectively; 150 mg/kg of R. vomitoria, a combination of 150 mg/kg of R. vomitoria and 200 mg/kg of G. latifolium, and a combination of 150 mg/kg of R. vomitoria and 200 mg/kg of V. amygdalina for seven days. On days 4-7 concurrent with treatment, spatial learning and memory test was carried out using the Morris water maze, and the animals were sacrificed twelve hours after the last treatment. Their sera were used for enzyme and other bio-molecules analysis.Results: There was no difference in spatial learning and memory. The activities of aspartate aminotrans­ferase, alanine aminotrans­ferase and alkaline phos­phatase, and the serum cholesterol and triglycerides levels were also not different compared to the control group.Conclusion: The dose and duration of administration of the extract of R. vomitoria either alone, or in combination with G. latifolium or V. amygdalina may not affect spatial learning or memory, or alter serum biomolecules.Asian Journal of Medical Sciences Vol.7(1) 2015 82-87

scholarly journals BITTER HERBS OF EASTERN NIGERIA (GONGRONEMA LATIFOLIUM, VERNONIA AMYGDALINA AND VITEX DONIANA): A REVIEW

2018 ◽  
Vol 15 (3) ◽  
pp. 47
Author(s):  
Asuzu Chinwe U.
Keyword(s):  
Key Words ◽  
Traditional Method ◽  
Human Consumption ◽  
Vernonia Amygdalina ◽  
South Eastern ◽  
Electronic Search ◽  
Anti Cancer ◽  
Large Audience ◽  
Vitex Doniana ◽  
Gongronema Latifolium

Background: The article is a review of three bitter vegetables consumed in South-eastern Nigeria (Gongronema latifolium, Vernonia amygdalina and Vitex doniana). These vegetables are not very palatable to taste but are highly famed because of the myriad of illnesses that they are reputed to cure and manage. The different aspects of these vegetables reviewed are their ethnobotany, zoo pharmacology, bioactivity, phytochemistry and toxicity. Materials and method: The literatures consulted were searched using electronic search engines (Google, Google scholar and Pubmed). Substantial amount of literature was consulted but only those directly related to the main review were selected. Result: The review revealed that the three bitter vegetables possessed phytochemicals like saponins, flavonoids, alkaloids among others that justify the claims of curing and managing many of the illnesses that traditional folks attribute to them. From literature, antimicrobial, antinflammatory, antidiabetic, antioxidant and anti cancer activities were attributed to these three bitter herbs. Antinutritional substances like phytate and oxalate reported in these herbs were not regarded as harmful for human consumption because of the traditional method of processing the vegetables by squeeze washing in several changes of water. Conclusion: The three bitter herbs are regarded as beneficial for human consumption and the information should be disseminated to a large audience. Key words: V. amygdalina, V. doniana, G.

The Effect of Gongronema Latifolum (Utazi) on Some Haematological Parameters of Rabbit

2020 ◽  
Author(s):  
Obeagu Emmanuel Ifeanyi
Keyword(s):  
Mean Value ◽  
Control Group ◽  
Mean Values ◽  
Platelet Counts ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Differential White Blood Cell ◽  
Group D ◽  
Gongronema Latifolium

The hematological features of Gongronema latifolium, aqueous leaves extract was evaluated using standard methods. After 10 days of consecutive infusions into 9 experimental animals (rabbits). The rabbits were monitored and the following parameters determined; hemoglobin (HB), PCV, Platelet, WBC, Differential White Blood Cell. The Rabbits were grouped into 4, one consisting of control (group A), group B was fed with 0.5 mg/kg, group C with 1.0 mg/kg, and Group D with 1.5mg/kg of the aqueous extract of Gongronemalatifolium. The mean values obtained for hemoglobin estimation for the control group is 5.9 ± 4.1 g/dl, 9.1 ± 2.9 g/dl for group B 10.2 ± 1.8 g/dl for group C and 12.8 ± 0.1 g/dl for group D with no significant increase on the PCV estimation, the mean value for the control (group A) is 17.7 ± 12.3%, 27.3 ± 8.7% for group B, group C (30.6 ± 5.4%) and D (28.4 ± 0.3) show increase that statistically significant (p > 0.01). the platelet counts of group C (600 ± 0 x 109/L) and D(600 ± 0 x 109/L) show significant increase (p > 0.01) when compared with the control (600 ± 00). But the platelet value of group B (550 ± 50 x 109/L) shows no difference. No significant changes were observed in the White Blood Counts of the test groups B (3.5 ± 0.5 x 109/L), C (1.9 + 2.1 x 109/L) and D(3.6 ± 0.4) when compared with the control group (2.9 ± 1.9). The values obtained from the differential White Blood Counts (Neutrophils, Lymphocytes, Eosinophils and Monocytes) were not significant. Therefore, Gongronemalatifolium, when properly taken as a nutritional diet, causes beneficial changes on hemoglobin, packed cell volumes and platelet counts of consumers.

Comparative Effects of Aqueous and Ethanolic Leaf Extracts of Gongronema latifolium on Serum Kidney and Liver Biomarkers of Normal Male Rats

2011 ◽  
Vol 4 (7) ◽  
pp. 540-547 ◽  
Author(s):  
C.O. Nwangwu Spencer ◽  
J. Josiah Sunday . ◽  
E. Abubakar Teslimat ◽  
O. Ajeigbe Kazeem ◽  
O. Osakwe Eguagie ◽  
...  
Keyword(s):  
Male Rats ◽  
Normal Male ◽  
Leaf Extracts ◽  
Gongronema Latifolium
Sign in / Sign up

Export Citation Format

Share Document