scholarly journals Haemostatic And Haematological Indices Of Aqueous Extract Of Gongronema Latifolium On Female Albino Rat

2013 ◽  
Vol 8 (1) ◽  
pp. 61-63
Author(s):  
Oguwike F.N ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Onu P. N.

This experiment was conducted to determine the effect of aqueous extract of Telfairia occidentalis (Fluted Pumpkin) leaf on the performance and haematological indices of starter broilers. A total of 200, 8-day-old broiler chicks were randomly allotted to five (5) treatments, each with 4 replicate groups containing 10 chicks and fed with standard starter broiler diets. Telfaria occidentalis leaves extract (FPLE) was added at 0, 40, 80, 120, and 160 mL/litre of drinking water. Growth performance and haematological indices were evaluated. Results showed that there was significant () difference in weight gain, feed conversion, and protein efficiency ratios of the birds among the treatments. Birds fed 80 ml FPLE/litre of water had significantly the highest weight gain and the best feed conversion and protein efficiency ratios. There was no significant () variations in the feed and water intakes of the birds. Results also show no significant () difference in haematological indices of birds among the treatments. The results of this study indicate that, for enhanced weight gain and feed conversion efficiency, birds should be fed 80 mL FPLE/litre of water.


Author(s):  
Ani Onuabuchi Nnenna ◽  
Ani Okwudili ◽  
Okwuosa Chukwugozie Nwachukwu

This study was aimed to investigate the effect of high sub-chronic doses of the aqueous and methanol leaf extracts of Loranthus micranthus on biochemical parameters of albino rats. Acute toxicity studies were performed according to standard methods. The animals were divided into 5 groups (n = 5). Aqueous and methanol extracts of L. micranthus leaves were administered in doses of 1000 and 2000 mg/kg body weight to four groups of rats respectively for 30 days through the intraperitoneal route. The fifth group served as control and received saline (5 ml/kg b.w, i.p). Blood samples were collected by retrorbital puncture and analyzed for biochemical and haematological parameters using assay kits. Acute toxicity studies indicated that both extracts had an LD50 >           5000 mg/kg. The results indicated significant (p<0.001) increases in alkaline phosphatase serum levels in both extract treated groups. The extracts also produced significant elevation in serum bilirubin levels when compared with normal control (p<0.05). Both extracts did not affect the levels of alanine and aspartate transaminases significantly (p>0.05). There were significant increase in the serum levels of urea in the extracts treated rats (p<0.05; p<0.01). The 2000 mg/kg aqueous extract produced significant increases in mean serum chloride and bicarbonate levels of treated rats when compared with control (p<0.01). The extracts produced significant decrease in the serum creatine kinase levels of treated rats in a non-dose related manner when compared with control (p<0.05). There were no significant changes in sodium and potassium levels of treated rats. The methanol extract had no significant effect on the haematological indices studied. The aqueous extract produced significant reductions in the haemoglobin and PCV of treated rats (p< 0.01). The total and differential leucocyte counts were not affected by extract treatment (p>0.05). From these results, the extracts caused significant biochemical changes but were not cytotoxic to leucocyte cell lines. Therefore, there should be caution in the long term use of these extracts.


2019 ◽  
Vol 57 (1) ◽  
pp. 604-611 ◽  
Author(s):  
Basiru O. Ajiboye ◽  
Babatunji E. Oyinloye ◽  
Precious E. Agboinghale ◽  
Sunday A. Onikanni ◽  
Emeka Asogwa ◽  
...  

2017 ◽  
Vol 11 (20) ◽  
pp. 250-259 ◽  
Author(s):  
E. Joshua Parker ◽  
L. Ogara Amaechi ◽  
C. Nkwocha Chinelo ◽  
O. Nduka Florence ◽  
C. Okoli Prisca ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document