The international quality assurance program (IRTIQAS) for the assay of immunoreactive trypsin in dried blood spots

1991 ◽  
Vol 11 (S7) ◽  
pp. 72-75 ◽  
Author(s):  
Mary E. Heeley ◽  
Georges Travert ◽  
Catherine Ferre ◽  
Francoise Lemonnier
1981 ◽  
Vol 113 (2) ◽  
pp. 111-121 ◽  
Author(s):  
Jeanette R. Crossley ◽  
Patricia A. Smith ◽  
Brian W. Edgar ◽  
Peter D. Gluckman ◽  
Robert B. Elliott

1990 ◽  
Vol 23 (3) ◽  
pp. 213-219 ◽  
Author(s):  
Giulio Cabrini ◽  
Fabio Pederzini ◽  
Laura Perobelli ◽  
Gianni Mastella

1980 ◽  
Vol 10 (3) ◽  
pp. 511-519 ◽  
Author(s):  
Roberto Dominici ◽  
Fabrizio Monaco ◽  
Silvana Morano ◽  
Italo Antonozzi

Author(s):  
P. Chaillet ◽  
R. Zachariah ◽  
K. Harries ◽  
E. Rusanganwa ◽  
A.D. Harries

2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Pieter W Smit ◽  
Thomas van der Vlis ◽  
David Mabey ◽  
John Changalucha ◽  
Julius Mngara ◽  
...  

Bioanalysis ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 99-109 ◽  
Author(s):  
Stuart J Moat ◽  
Catherine Dibden ◽  
Lesley Tetlow ◽  
Caroline Griffith ◽  
Jim Chilcott ◽  
...  

Aim: Dried blood spots (DBS) are used for the analysis of more than 2000 biomarkers. We assessed a range of analyte concentrations and diameters of DBS. Materials & methods: DBS samples were created by the application of increasing volumes of whole blood prepared by the UK NEQAS Quality Assurance Laboratory. Samples were analyzed in four separate laboratories. Results: Volumes less than 25 μl (8 mm) and more than 75 μl (14 mm) created unsatisfactory analytical biases. Results obtained from peripheral subpunches tended to be higher than those from a central subpunch. Conclusion: DBS diameters formed from nonvolumetric application of blood to filter paper can be used to assess whether measurement bias will be within acceptable limits according to the analyte being quantified. DBS received for newborn screening in the UK with diameters less than 8 mm and those more than 14 mm should be rejected.


2020 ◽  
Vol 6 (1) ◽  
pp. 8 ◽  
Author(s):  
Georges Travert ◽  
Mary Heeley ◽  
Anthony Heeley

This review summarises the trajectory of neonatal screening strategies for the detection of cystic fibrosis (CF) using the measurement of Immunoreactive Trypsin (IRT) in dried blood spots (DBS) from 1979 until the beginning of the 21st century when newborn screening (NBS) programmes started to spread throughout many countries, using IRT measurement combined with a CF genotype analysis of DBS.


1998 ◽  
Vol 233 (1-2) ◽  
pp. 9-14
Author(s):  
J. A. Broadway ◽  
D. A. Chambless ◽  
Yu. A. Sapozhnikov ◽  
S. N. Kalmykov

2014 ◽  
Vol 53 (3) ◽  
pp. 964-966 ◽  
Author(s):  
Lisa M. Prach ◽  
Adrian Puren ◽  
Sheri A. Lippman ◽  
Sergio Carmona ◽  
Sophie Stephenson ◽  
...  

An external quality assurance program was developed for HIV-1 RNA viral load measurements taken from dried blood spots using a reference panel and field-collected specimens. The program demonstrated that accurate and reproducible quantitation can be obtained from field-collected specimens. Residual proviral DNA may confound interpretation in virologically suppressed subjects.


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