Invasive mechanical ventilation for acute respiratory failure in children with cystic fibrosis: Outcome analysis and case-control study

2002 ◽  
Vol 34 (4) ◽  
pp. 297-303 ◽  
Author(s):  
Ariel Berlinski ◽  
Leland L. Fan ◽  
Claudia A. Kozinetz ◽  
Christopher M. Oermann
Keyword(s):  
Cystic Fibrosis ◽  
Mechanical Ventilation ◽  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Case Control Study ◽  
Invasive Mechanical Ventilation ◽  
Case Control ◽  
Outcome Analysis ◽  
Control Study

scholarly journals Association between cardiometabolic disease and severe COVID-19: a nationwide case–control study of patients requiring invasive mechanical ventilation

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e044486 ◽  
Author(s):  
Per Svensson ◽  
Robin Hofmann ◽  
Henrike Häbel ◽  
Tomas Jernberg ◽  
Per Nordberg
Keyword(s):  
Type 2 Diabetes ◽  
Mechanical Ventilation ◽  
Case Control Study ◽  
Invasive Mechanical Ventilation ◽  
Population Based ◽  
Case Control ◽  
Population Type ◽  
Susceptible Patient ◽  
Control Study

AimsThe risks associated with diabetes, obesity and hypertension for severe COVID-19 may be confounded and differ by sociodemographic background. We assessed the risks associated with cardiometabolic factors for severe COVID-19 when accounting for socioeconomic factors and in subgroups by age, sex and region of birth.Methods and resultsIn this nationwide case–control study, 1.086 patients admitted to intensive care with COVID-19 requiring mechanical ventilation (cases), and 10.860 population-based controls matched for age, sex and district of residency were included from mandatory national registries. ORs with 95% CIs for associations between severe COVID-19 and exposures with adjustment for confounders were estimated using logistic regression. The median age was 62 years (IQR 52–70), and 3003 (24.9%) were women. Type 2 diabetes (OR, 2.3 (95% CI 1.9 to 2.7)), hypertension (OR, 1.7 (95% CI 1.5 to 2.0)), obesity (OR, 3.1 (95% CI 2.4 to 4.0)) and chronic kidney disease (OR, 2.5 (95% CI 1.7 to 3.7)) were all associated with severe COVID-19. In the younger subgroup (below 57 years), ORs were significantly higher for all cardiometabolic risk factors. The risk associated with type 2 diabetes was higher in women (p=0.001) and in patients with a region of birth outside European Union(EU) (p=0.004).ConclusionDiabetes, obesity and hypertension were all independently associated with severe COVID-19 with stronger associations in the younger population. Type 2 diabetes implied a greater risk among women and in non-EU immigrants. These findings, originating from high-quality Swedish registries, may be important to direct preventive measures such as vaccination to susceptible patient groups.Trial registration numberClinicaltrial.gov (NCT04426084).

scholarly journals Effectiveness of early rehabilitation on patients with chronic obstructive lung disease and acute respiratory failure in intensive care units: A case–control study

2019 ◽  
Vol 16 ◽  
pp. 147997311882031
Author(s):  
Willy Chou ◽  
Chih-Cheng Lai ◽  
Kuo-Chen Cheng ◽  
Kuo-Shu Yuan ◽  
Chin-Ming Chen ◽  
...  
Keyword(s):  
Intensive Care ◽  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Intensive Care Units ◽  
Case Control Study ◽  
Case Control ◽  
Early Rehabilitation ◽  
Chronic Obstructive ◽  
Copd Patients ◽  
Control Study

The effect of early rehabilitation on the outcome of patients with chronic obstructive pulmonary disease (COPD) and acute respiratory failure (ARF) in intensive care units (ICUs) remains unclear. We examined the effect of early rehabilitation on the outcomes of COPD patients requiring mechanical ventilation (MV) in the ICU. This retrospective, observational, case–control study was conducted in a medical center with a 19-bed ICU. The records of all 105 ICU patients with COPD and ARF who required MV from January to December 2011 were examined. The outcomes (MV duration, rates of successful weaning and survival, lengths of ICU and hospital stays, and medical costs) were recorded and analyzed. During the study period, 35 patients with COPD underwent early rehabilitation in the ICU and 70 demographically and clinically matched patients with similar COPD stage, cause of intubation, type of respiratory failure, and levels of disease severity who had not undergone early rehabilitation in the ICU were selected as comparative controls. Multiple regression analysis showed that early rehabilitation was significantly negatively associated with MV duration. Early rehabilitation for COPD patients in the ICU with ARF shortened the duration of their MV.

scholarly journals Reduced adiponectin levels in patients with COVID‐19 acute respiratory failure: A case‐control study

2021 ◽  
Vol 9 (7) ◽  
Author(s):  
Sean M. Kearns ◽  
Katelyn W. Ahern ◽  
James T. Patrie ◽  
William B. Horton ◽  
Thurl E. Harris ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Intravenous Lipid Emulsions Affect Respiratory Outcome in Preterm Newborn: A Case-Control Study

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1243
Author(s):  
Giovanni Boscarino ◽  
Maria Giulia Conti ◽  
Francesca De Luca ◽  
Maria Di Chiara ◽  
Giorgia Deli ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Birth Weight ◽  
Gestational Age ◽  
Case Control Study ◽  
Invasive Mechanical Ventilation ◽  
Case Control ◽  
Lipid Emulsions ◽  
Metabolic Complication ◽  
Respiratory Outcome ◽  
Control Study

(1) Background: Hypertriglyceridemia (HiTG) is a metabolic complication of intravenous lipid emulsions (ILEs) infusion. We aimed to evaluate the influence of HiTG on the respiratory outcome of preterm babies; (2) Methods: We enrolled, in a case–control study, newborns with gestational age <32 weeks or birth weight <1500 g, over a 3-year period. They were divided into cases and controls; cases were defined by the detection of HiTG defined as serum triglycerides (TG) value >150 mg/dL; (3) Results: We enrolled 40 cases and 105 controls. Cases had an increased incidence of bronchopulmonary dysplasia (30.0% vs. 14.3%, p < 0.05) and longer duration of invasive mechanical ventilation (7 days, 95% CI 4–10 days vs. 4 days, 95% CI 1–7 days, p < 0.01) compared to controls. Multivariate analysis confirmed that HiTG independently influenced the duration of invasive mechanical ventilation, also in the subgroups with gestational age ≤28 + 6/7 weeks or birth weight ≤1000 g; (4) Conclusion: Newborns with HiTG related to ILEs had a longer duration of invasive mechanical ventilation. Temporary suspension or reduction in ILEs in the case of HiTG is associated with an improvement of respiratory outcome.

scholarly journals Use of antipsychotics and the risk of acute respiratory failure among adults: A disease risk score‐matched nested case–control study

2020 ◽  
Vol 86 (11) ◽  
pp. 2204-2216 ◽  
Author(s):  
Meng‐Ting Wang ◽  
Chen Wei Lin ◽  
Chen‐Liang Tsai ◽  
Yun‐Han Wang ◽  
Jyun‐Heng Lai ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Risk Score ◽  
Case Control Study ◽  
Disease Risk ◽  
Case Control ◽  
Disease Risk Score ◽  
Nested Case Control ◽  
Control Study

Outcome of Respiratory Failure: A Case-Control Study

1996 ◽  
Vol 35 (4) ◽  
pp. 199-204
Author(s):  
Roberto Caballero ◽  
Reese H. Clark ◽  
Jean A. Wright
Keyword(s):  
Respiratory Failure ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

Incidence and risk factors of cancer in individuals with cystic fibrosis in the UK; a case-control study

2021 ◽  
Author(s):  
Olga Archangelidi ◽  
Paul Cullinan ◽  
Nicholas J. Simmonds ◽  
Emmanouil Mentzakis ◽  
Daniel Peckham ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cystic Fibrosis ◽  
Case Control Study ◽  
Case Control ◽  
The Uk ◽  
Control Study
Sign in / Sign up

Export Citation Format

Share Document