Preparation of oleic acid‐carboxymethyl cellulose sodium composite vesicle and its application in encapsulating nicotinamide

2021 ◽  
Author(s):  
Xiangnan Guo ◽  
Jisheng Yang
2018 ◽  
Vol 57 (44) ◽  
pp. 15046-15053 ◽  
Author(s):  
Jiyu Yang ◽  
Yanan Zheng ◽  
Linjuan Sheng ◽  
Hongmei Chen ◽  
Lijuan Zhao ◽  
...  

2018 ◽  
Vol 11 (3) ◽  
pp. 124
Author(s):  
Shella Permatasari Santoso ◽  
Niko Sanjaya ◽  
Aning Ayucitra

The use of cassava peels as raw material for Sodium Carboxymethyl Cellulose productionCassava peels are abundantly available and may be used as an lowcost cellulose source (80-85% cellulose per weight cassava peel). the study was to evaluate the effect of the concentration of sodium hydroxide, sodium chloroacetate, and temperature reaction on the sodium carboxymethyl cellulose (sodium-CMC) characteristics i.e. yield, purity, and degree of substitution in sodium-CMC preparation.  Sodium-CMC functional group was determined using FTIR spectrophotometer. Cassava peels was dried and grounded to 50 mesh. Lignin was eliminated from cassava peel by extraction of grounded cassava peel with 10% NaOH at 35 °C for 5 h. Cassava peel free lignin was then re-extracted using 10% of acetic acid and sodium chloride at 75 °C for 1 h, thus cellulose free hemicellulose was obtained. Alkalization at 30 °C for 90 min was performed by adding sodium hydroxyde at 10-40% to cellulose using isopropyl alcohol solvent. Following this, etherification was conducted by adding sodium chloroacetate of 1-5 g at 50-80 °C for 6 h. As result, the highest purity of sodium-CMC (96.20%) was obtained from alkalization using 20% of sodium hydroxide and etherification using 3 g sodium chloroacetate at 70 °C. Sodium-CMC yield was 22% and degree of substitution 0.705.Keywords: cassava peel, carboxymethyl cellulose, sodium-CMC, etherification AbstrakKulit singkong merupakan sumber selulosa yang berlimpah dan murah, dengan kadar selulosa 80-85% dari berat kulit singkong. Tujuan penelitian ini adalah memanfaatkan selulosa dalam kulit singkong sebagai bahan baku pembuatan natrium karboksimetil selulosa (Na-CMC), mempelajari pengaruh natrium hidroksida, natrium kloroasetat serta suhu pada karakteristik Na-CMC seperti perolehan, kemurnian, dan derajat substitusi, serta menentukan kondisi operasi optimum untuk pembuatan Na-CMC berdasarkan kemurnian Na-CMC terbesar. Gugus fungsi Na-CMC ditentukan menggunakan Fourier Transform Infrared Spectra. Mula-mula, kulit singkong dikeringkan dan dihancurkan sehingga berukuran 50 mesh. Kulit singkong diekstraksi dengan NaOH 10% di suhu 35 °C selama 5 jam, untuk melarutkan lignin. Kulit singkong bebas lignin diekstrak dengan asam asetat 10% dan natrium klorida dengan pemanasan 750 °C selama 1 jam untuk melarutkan hemiselulosa sehingga didapatkan selulosa. Alkalisasi dilakukan dengan mereaksikan selulosa dengan NaOH 10-40% dengan pelarut isopropil alkohol pada suhu 30 °C selama 90 menit, dilanjutkan eterifikasi dengan natrium kloroasetat 1-5 g pada suhu 50-80 °C selama 6 jam. Berdasarkan hasil penelitian, karakteristik Na-CMC terbaik didapatkan dari alkalisasi selulosa menggunakan NaOH 20% serta eterifikasi menggunakan 3 g natrium kloroasetat pada suhu 70 °C. Perolehan Na-CMC yang didapat adalah sebesar 22%, kemurnian 96,20%, derajat substitusi 0,705; termasuk dalam grade kedua menurut SNI 06-3736-1995.Kata kunci: kulit singkong, karboksimetil selulosa, Na-CMC, eterifikasi


2020 ◽  
Vol 5 (3) ◽  
pp. 167
Author(s):  
Safrida Safrida ◽  
Khairil Khairil ◽  
Fani Fardinita

This study determined the antihyperglycemic and antioxidant activity of nanoemulsion extracts of M. affine leaves in alloxan-induced rats. This research used 24 male Wistar rats around three months old which grouped as normal (untreated), negative control (treated with carboxymethyl cellulose sodium/Na-CMC,), positive control (treated with glibenclamide), and various concentration (30, 60, and 90%) of nanoemulsion extract of M. affine leaves groups. The extract of M. affine leaves had an antioxidant activity with IC50 5.30 ppm, categorized as a very strong antioxidant. Furthermore, the administration of this extract decreased glucose levels in antihyperglycemic rats.  We concluded that M. affine leaves extract potential as antioxidants and be developed as an ingredient for diabetic drugs.


RSC Advances ◽  
2016 ◽  
Vol 6 (55) ◽  
pp. 50061-50069 ◽  
Author(s):  
Jingjing Liu ◽  
Huijuan Chu ◽  
Hongliang Wei ◽  
Hongzheng Zhu ◽  
Gang Wang ◽  
...  

Carboxymethyl cellulose sodium (CMCNa)/graphene oxide (GO) hydrogel microparticles (CGs) with the diameter of 2.2–3.6 μm were prepared facilely via spray drying and used as adsorbents for water purification.


2019 ◽  
Vol 131 ◽  
pp. 01114
Author(s):  
Dan-min Fan ◽  
Zhi-long Yang

The main raw materials of rose milk beverage are Yunnan red roses and milk. By analyzing the proportions of rose juice to milk, sucrose, citric acid and sodium alginate, and by taking flavor, taste, color and tissue state as the evaluation parameters, we conducted single-factor experiments and orthogonal experiments, and identified the optimum formula of rose milk beverage: 8% rose juice, 6% milk, 10% sucrose, 0.1% citric acid, and 0.15% compound stabilizer (sodium carboxymethyl cellulose, sodium alginate in the proportion of 1:1). Unique flavor of rose milk beverage with rich nutrition can be prepared by using the optimum formula we obtained.


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