scholarly journals Discussion on ‘Automatic and Controlled Processes in Behavioural Control: Implications for Personality Psychology’ by Corr

2010 ◽  
Vol 24 (5) ◽  
pp. 404-422 ◽  
Keyword(s):  
Nervous System ◽  
Personality Traits ◽  
Behavioural Inhibition ◽  
Personality Psychology ◽  
Controlled Processes ◽  
Behavioural Approach ◽  
Controlled Processing ◽  
Freeze System ◽  
Behavioural Inhibition System

This comment critiques Corr's (2010) characterization of the personality traits associated with the elements of Gray's conceptual nervous system: The behavioural inhibition system (BIS), the behavioural approach system (BAS) and the fight–flight–freeze system (FFFS). Most attention is paid to the FFFS because least is known about its manifestation in personality. Additionally, I suggest that Corr's framework for understanding automatic and controlled processing is useful for developing theories of the biological systems underlying traits that are not directly related to BIS, BAS and FFFS. Copyright © 2010 John Wiley & Sons, Ltd.

From BIS/BAS to the big five

2006 ◽  
Vol 20 (4) ◽  
pp. 255-270 ◽  
Author(s):  
Dirk J. M. Smits ◽  
P. D. Boeck
Keyword(s):  
Individual Differences ◽  
Big Five ◽  
The Other ◽  
Behavioural Inhibition ◽  
Behavioural Approach ◽  
Two Samples ◽  
Two Systems ◽  
Behavioural Inhibition System

Gray (1987) proposed two systems that underlie much of our behaviour and personality. One system relates to avoidance or withdrawal behaviour, called the Behavioural Inhibition System (BIS), whereas the other system relates to approach behaviour, called the Behavioural Approach System (BAS). In two samples, it was investigated whether individual differences in surface of personality as described by the Big Five can be explained by BIS/BAS. Neuroticism and Extraversion could be explained well by BIS/BAS, but also for Agreeableness and Conscientiousness consistent findings were obtained. Copyright © 2006 John Wiley & Sons, Ltd.

Automatic and Controlled Processes in Behavioural Control: Implications for Personality Psychology

2010 ◽  
Vol 24 (5) ◽  
pp. 376-403 ◽  
Author(s):  
Philip J. Corr
Keyword(s):  
Conscious Experience ◽  
Behavioural Control ◽  
Conscious Awareness ◽  
Behavioural Inhibition ◽  
Personality Psychology ◽  
Controlled Processing ◽  
Theoretical Perspectives ◽  
The Relationship ◽  
Reflective Processing ◽  
Theoretical Issues

This paper highlights a number of unresolved theoretical issues that, it is argued, continue to impede the construction of a viable model of behavioural control in personality psychology. It is contended that, in order to integrate motivation, emotion, cognition and conscious experience within a coherent framework, two major issues need to be recognised: (a) the relationship between automatic (reflexive) and controlled (reflective) processing and (b) the lateness of controlled processing (including the generation of conscious awareness)—phenomenally, such processing seems to ‘control’ behaviour, but experimentally it can be shown to postdate the behaviour it represents. The implications of these two major issues are outlined, centred on the need to integrate theoretical perspectives within personality psychology, as well as the greater unification of personality psychology with general psychology. A model of behavioural control is sketched, formulated around the concept of the behavioural inhibition system (BIS), which accounts for: (a) why certain stimuli are extracted for controlled processing (i.e. those that are not ‘going to plan’, as detected by an error mechanism) and (b) the function of controlled processing (including conscious awareness) in terms of adjusting the cybernetic weights of automatic processes (which are always in control of immediate behaviour) which, then, influence future automatically controlled behaviour. The relevance of this model is illustrated in relation to a number of topics in personality psychology, as well related issues of free–will and difficult–to–control behaviours. Copyright © 2010 John Wiley & Sons, Ltd.

scholarly journals PERFECTIONISM IN THE CONTEXT OF THE REVISED REINFORCEMENT SENSITIVITY THEORY

2021 ◽  
pp. 039
Author(s):  
Kristina Ranđelovic ◽  
Snežana Stojiljković
Keyword(s):  
Personality Traits ◽  
Hierarchical Regression ◽  
Reinforcement Sensitivity Theory ◽  
Behavioural Inhibition ◽  
Total Percentage ◽  
Sensitivity Theory ◽  
Reinforcement Sensitivity ◽  
Explained Variance ◽  
Behavioural Inhibition System

The main goal of this research was to examine the role of personality traits in predicting the two aspects of perfectionism – maladaptive evaluation concerns and positive strivings. Personality traits were postulated by the Revised Reinforcement Sensitivity Theory, while the dimensions of perfectionism were defined by the Model of Perfectionism developed by Frost et al. The sample consisted of 299 students of the Faculty of Philosophy in Niš (79.3% were female), aged 19 to 29 years (M = 20.34; SD = 1.83). The instruments used were: the Reinforcement Sensitivity Questionnaire (RSQ), and the Multidimensional Perfectionism Scale (MPS). The main takeaways of this research indicate that the Behavioural Inhibition System (BIS) is the strongest and positive correlate of maladaptive evaluation concerns, followed by Freeze and Fight. Unlike personality defence systems, the Behavioural Approach System (BAS) shows a negative correlation with the abovementioned criterion. The total percentage of explained variance for maladaptive evaluation concerns is 23%. When positive strivings are used as the criterion, BAS is seen as a positive correlate only in the first step of the hierarchical regression analysis. However, Flight and Fight represent consistent and positive correlates of this criterion. The total percentage of explained variance for positive strivings is 6.9%. The findings are consistent with the Revised Reinforcement Sensitivity Theory and available empirical findings from previous studies. Moreover, the results indicate that in the context of the abovementioned personality theory, maladaptive evaluation concerns and positive strivings can be understood as maladaptive forms of perfectionism, which deviates from previous understandings of perfectionism.

Acid-Sensing Ion Channels

2020 ◽  
Author(s):  
Stefan Gründer
Keyword(s):  
Nervous System ◽  
Ion Channels ◽  
Excitatory Synapses ◽  
Detailed Characterization ◽  
High Affinity ◽  
Acid Sensing Ion Channels ◽  
Long Time ◽  
Pathological Pain

Acid-sensing ion channels (ASICs) are proton-gated Na+ channels. Being almost ubiquitously present in neurons of the vertebrate nervous system, their precise function remained obscure for a long time. Various animal toxins that bind to ASICs with high affinity and specificity have been tremendously helpful in uncovering the role of ASICs. We now know that they contribute to synaptic transmission at excitatory synapses as well as to sensing metabolic acidosis and nociception. Moreover, detailed characterization of mouse models uncovered an unanticipated role of ASICs in disorders of the nervous system like stroke, multiple sclerosis, and pathological pain. This review provides an overview on the expression, structure, and pharmacology of ASICs plus a summary of what is known and what is still unknown about their physiological functions and their roles in diseases.

scholarly journals Molecular Modeling of Histamine Receptors—Recent Advances in Drug Discovery

Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1778
Author(s):  
Pakhuri Mehta ◽  
Przemysław Miszta ◽  
Sławomir Filipek
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Molecular Modeling ◽  
Molecular Targets ◽  
Histamine Receptors ◽  
Experimental Characterization ◽  
Complex Disorders ◽  
Theoretical Investigations ◽  
Recent Developments

The recent developments of fast reliable docking, virtual screening and other algorithms gave rise to discovery of many novel ligands of histamine receptors that could be used for treatment of allergic inflammatory disorders, central nervous system pathologies, pain, cancer and obesity. Furthermore, the pharmacological profiles of ligands clearly indicate that these receptors may be considered as targets not only for selective but also for multi-target drugs that could be used for treatment of complex disorders such as Alzheimer’s disease. Therefore, analysis of protein-ligand recognition in the binding site of histamine receptors and also other molecular targets has become a valuable tool in drug design toolkit. This review covers the period 2014–2020 in the field of theoretical investigations of histamine receptors mostly based on molecular modeling as well as the experimental characterization of novel ligands of these receptors.

scholarly journals Immunological and Molecular Characterization of Goα-like Proteins in the Drosophila Central Nervous System

1989 ◽  
Vol 264 (31) ◽  
pp. 18552-18560 ◽  
Author(s):  
N C Thambi ◽  
F Quan ◽  
W J Wolfgang ◽  
A Spiegel ◽  
M Forte
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Molecular Characterization

scholarly journals Molecular cloning and analysis of l(1)ogre, a locus of Drosophila melanogaster with prominent effects on the postembryonic development of the central nervous system.

Genetics ◽  
1990 ◽  
Vol 126 (4) ◽  
pp. 1033-1044 ◽  
Author(s):  
T Watanabe ◽  
D R Kankel
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Postembryonic Development ◽  
P Element ◽  
Reading Frame ◽  
Isolation And Characterization ◽  
The Central Nervous System ◽  
Highly Hydrophobic ◽  
Conceptual Translation

Abstract Previous genetic studies have shown that wild-type function of the l(1)ogre (lethal (1) optic ganglion reduced) locus is essential for the generation and/or maintenance of the postembryonic neuroblasts including those from which the optic lobe is descended. In the present study molecular isolation and characterization of the l(1)ogre locus was carried out to study the structure and expression of this gene in order to gain information about the nature of l(1)ogre function and its relevance to the development of the central nervous system. About 70 kilobases (kb) of genomic DNA were isolated that spanned the region where l(1)ogre was known to reside. Southern analysis of a l(1)ogre mutation and subsequent P element-mediated DNA transformation mapped the l(1)ogre+ function within a genomic fragment of 12.5 kb. Northern analyses showed that a 2.9-kb message transcribed from this 12.5-kb region represented l(1)ogre. A 2.15-kb portion of a corresponding cDNA clone was sequenced. An open reading frame (ORF) of 1,086 base paris was found, and a protein sequence of 362 amino acids with one highly hydrophobic segment was deduced from conceptual translation of this ORF.

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