Null cell adenomas of the pituitary gland. An immunohistochemical study

1989 ◽  
Vol 158 (3) ◽  
pp. 213-217 ◽  
Author(s):  
Ruth Holm ◽  
Jahn M. Nesland ◽  
Arne Attramadal ◽  
Johan Halse ◽  
Jan V. Johannessen
Keyword(s):  
Pituitary Gland ◽  
Immunohistochemical Study ◽  
Null Cell ◽  
Null Cell Adenomas

scholarly journals Intermediate Filaments in the Human Pituitary Gland: An Immunohistochemical Study

1990 ◽  
Vol 17 (2) ◽  
pp. 131-136 ◽  
Author(s):  
W.C. Halliday ◽  
S.L. Asa ◽  
K. Kovacs ◽  
B.W. Scheithauer
Keyword(s):  
Pituitary Gland ◽  
Intermediate Filaments ◽  
Immunohistochemical Study ◽  
Serial Sections ◽  
Null Cell ◽  
Human Pituitary ◽  
Human Pituitary Gland ◽  
Immunohistochemical Techniques ◽  
Corticotroph Adenomas ◽  
Small Subpopulation

ABSTRACT:Normal pituitaries, pituitaries showing CHC and selected adenomas were assessed for their possible content of intermediate filaments (IF), using immunohistochemical techniques. Normal pituitaries were stained for each of the five known IF (Cytokeratins (CK), glial fibrillary acidic protein (GFAP), desmin, vimentin, and neurofilaments (NF)). Desmin could not be demonstrated, and NF staining was limited to processes in the posterior gland. In serial sections, CK was demonstrated in some corticotrophs, somatotrophs, and lactotrophs. Vimentin was limited to processes in the posterior gland. Folliculo-stellate cells (FSC), demonstrated by staining for SlOO protein, exhibited a small subpopulation staining for CK, and another subpopulation staining for GFAP. GFAP was also demonstrated in glial processes in the posterior gland. Cells showing Crooke's hyaline change stained intensely for CK. Null cell adenomas did not stain for CK. Corticotroph adenomas, somatotroph adenomas, with or without fibrous bodies, and lactotroph adenomas contain CK-immunoreactive cells. We conclude that CK is the major IF present in the anterior pituitary gland, within some normal corticotrophs, somatotrophs and lactotrophs, and also in adenomas derived from these cells.

Computer-assisted microscope analysis of feulgen-stained nuclei in gonadotroph adenomas and null-cell adenomas of the pituitary gland

1997 ◽  
Vol 8 (2) ◽  
pp. 109-120 ◽  
Author(s):  
M. Beatriz S. Lopes ◽  
Isabelle Salmon ◽  
Nathalie Nagy ◽  
Christine Decaestecker ◽  
Jean-Lambert Pasteels ◽  
...  
Keyword(s):  
Pituitary Gland ◽  
Computer Assisted ◽  
Null Cell ◽  
Microscope Analysis ◽  
Null Cell Adenomas

Null Cell Adenomas of the Pituitary Gland: an Institutional Review of Their Clinical Imaging and Behavioral Characteristics

2014 ◽  
Vol 26 (1) ◽  
pp. 63-70 ◽  
Author(s):  
James A. Balogun ◽  
Eric Monsalves ◽  
Kyle Juraschka ◽  
Kashif Parvez ◽  
Walter Kucharczyk ◽  
...  
Keyword(s):  
Pituitary Gland ◽  
Behavioral Characteristics ◽  
Null Cell ◽  
Clinical Imaging ◽  
Institutional Review ◽  
Null Cell Adenomas

Immunonegative "Null Cell" Adenomas and Gonadotropin (Gn) Subunit (SUs) Immunopositive Adenomas Share Frequent Expression of Multiple Transcription Factors

2006 ◽  
Vol 17 (1) ◽  
pp. 35-44 ◽  
Author(s):  
Yudo Ishii ◽  
Masanori Suzuki ◽  
Susumu Takekoshi ◽  
Noboru Egashira ◽  
Michio Yamazaki ◽  
...  
Keyword(s):  
Transcription Factors ◽  
Null Cell ◽  
Null Cell Adenomas

Null cell adenomas, oncocytomas, and gonadotroph adenomas of the human pituitary: An immunocytochemical and ultrastructural anafysis of 300 cases

1993 ◽  
Vol 4 (1) ◽  
pp. 20-27 ◽  
Author(s):  
George Kontogeorgos ◽  
Kalman Kovacs ◽  
Eva Horvath ◽  
Bernd W. Scheithauer
Keyword(s):  
Null Cell ◽  
Human Pituitary ◽  
Null Cell Adenomas
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