scholarly journals Towards a Fully Integrated Lab-On-A-Chip

2018 ◽  
Vol 13 (1) ◽  
pp. 28-31
Author(s):  
Joerg Nestler ◽  
Harald Peter ◽  
Frank Bier
2019 ◽  
Vol 653 ◽  
pp. 1223-1230 ◽  
Author(s):  
J. Gallardo-Gonzalez ◽  
A. Baraket ◽  
S. Boudjaoui ◽  
T. Metzner ◽  
F. Hauser ◽  
...  

2010 ◽  
Vol 93-94 ◽  
pp. 129-132 ◽  
Author(s):  
W. Sripumkhai ◽  
A. Lekwichai ◽  
Win Bunjongpru ◽  
S. Porntheeraphat ◽  
B. Tunhoo ◽  
...  

The on-chip platinum micro-heater prototypes for thermal cycling equipped with platinum temperature sensor are fabricated. The device has been designed, fabricated and characterized to explore the feasibility of the micro-heater for a fully integrated disposable lab-on-a-chip with the PCR module. The on-chip micro-heater demonstrates that the temperature transitions are shorter by comparison with the conventional PCR temperature routines.


2008 ◽  
Vol 1138 ◽  
Author(s):  
P. Martins ◽  
V. Cardoso ◽  
J. Serrado Nunes ◽  
L. Rebouta ◽  
G. Rocha ◽  
...  

AbstractThis paper reports on the incorporation and validation of a microagitation system based on a piezoelectric polymer, Poly(vinylidene fluoride) in its beta phase, β-PVDF, in a fully-integrated disposable lab-on-a-chip for point-of-care testing and monitoring of biochemical parameters in biological fluids. The lab-on-a-chip concept offers a novel approach for clinical analyses, especially in biological fluids analyses, due to its portability, ensuring that the analysis can be performed at any location with quick results. Its microagitation system performance was successfully demonstrated by quantitative measurements of uric acid in human urine, though other molecules or biological fluids can be also measured. The optimization tests prove that it is possible to use lower frequencies than resonance with no major changes in the mixing process. The effect of area and location within the lab-on-a-chip of the microagitation system was also considered.


2008 ◽  
Vol 57 ◽  
pp. 99-104 ◽  
Author(s):  
Vanessa F. Cardoso ◽  
P. Martins ◽  
Jivago Serrado-Nunes ◽  
L. Rebouta ◽  
José Gerardo Rocha ◽  
...  

This paper describes a fully-integrated lab-on-a-chip device for testing and monitoring biochemical parameters in biological fluids. The major innovation of this microdevice is the application of an acoustic microagitation technique with automatic electronic control based on a β-PVDF piezoelectric polymer placed underneath the microfluidic structures. Experimental results regarding the influence of the thickness of the polymer on the reaction rate of biological fluids are presented. Moreover, the study of the transmittance curve of β-PVDF with transparent conductive electrodes is also presented. Transparent electrodes are a constraint once the polymer is incorporate underneath the reaction chamber due to the analytical measurement by spectrophotometry.


2005 ◽  
Author(s):  
Soren Balslev ◽  
Brian Bilenberg ◽  
Daniel Nilsson ◽  
Anders M. Jorgensen ◽  
Anders Kristensen ◽  
...  

Lab on a Chip ◽  
2010 ◽  
Vol 10 (11) ◽  
pp. 1480 ◽  
Author(s):  
Jochen Hoffmann ◽  
Daniel Mark ◽  
Sascha Lutz ◽  
Roland Zengerle ◽  
Felix von Stetten

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Filippo Storti ◽  
Silvio Bonfadini ◽  
Luigino Criante

The Analyst ◽  
2015 ◽  
Vol 140 (16) ◽  
pp. 5781-5788 ◽  
Author(s):  
C. M. Gabardo ◽  
R. C. Adams-McGavin ◽  
O. M. Vanderfleet ◽  
L. Soleymani

Fully-integrated electro-fluidic systems with micro-/nano-scale features have a wide range of applications in lab-on-a-chip systems used for biosensing, biological sample processing, and environmental monitoring.


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