scholarly journals The Long-term impact of intrauterine growth restriction in a diverse US cohort of children: The EPOCH study

Obesity ◽  
2013 ◽  
Vol 22 (2) ◽  
pp. 608-615 ◽  
Author(s):  
Tessa L. Crume ◽  
Ann Scherzinger ◽  
Elizabeth Stamm ◽  
Robert McDuffie ◽  
Kimberly J. Bischoff ◽  
...  
Keyword(s):  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Intrauterine Growth ◽  
Long Term Impact

scholarly journals Consequences in Infants That Were Intrauterine Growth Restricted

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Erich Cosmi ◽  
Tiziana Fanelli ◽  
Silvia Visentin ◽  
Daniele Trevisanuto ◽  
Vincenzo Zanardo
Keyword(s):  
Intrauterine Growth Restriction ◽  
Placental Insufficiency ◽  
Growth Restriction ◽  
Growth Potential ◽  
Intrauterine Growth ◽  
Cardiovascular Abnormalities ◽  
Short And Long Term

Intrauterine growth restriction is a condition fetus does not reach its growth potential and associated with perinatal mobility and mortality. Intrauterine growth restriction is caused by placental insufficiency, which determines cardiovascular abnormalities in the fetus. This condition, moreover, should prompt intensive antenatal surveillance of the fetus as well as follow-up of infants that had intrauterine growth restriction as short and long-term sequele should be considered.

scholarly journals Whey Versus Casein as a Protein Source during the Weaning Period: Impact on Growth and Later Adiposity and Glucose Homeostasis in a Rat Model of Intrauterine Growth Restriction

Nutrients ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3399
Author(s):  
Yasaman Shahkhalili ◽  
Florence Blancher-Budin ◽  
Cathriona Monnard ◽  
Julie Moulin ◽  
José Sanchez-Garcia ◽  
...  
Keyword(s):  
Glucose Homeostasis ◽  
Intrauterine Growth Restriction ◽  
Early Life ◽  
Growth Restriction ◽  
Protein Source ◽  
Intrauterine Growth ◽  
Populations At Risk ◽  
Ad Libitum ◽  
The Impact

The impact of early life protein source (whey vs. casein) on short- and long-term glucose homeostasis and adiposity is unknown and was investigated in this study. At the end of the suckling period, non-IUGR (intrauterine growth restriction) and IUGR pups were separated from dams and were randomized into four groups. From age 21–49 days, non-IUGR and IUGR pups were fed ad-libitum chow or a semi-synthetic diet (20% from protein; casein or whey) and from age 50–199 days, all groups were fed ad-libitum chow. Food intake, body composition, glucose, and insulin homeostasis were assessed. Among the chow groups, IUGR had slower growth and higher fasting glucose at age 42 days, as well as higher fasting and AUC glucose at age 192 days relative to non-IUGR. The whey IUGR group had a slower growth rate and higher fasting glycemia in early life (age 21–49 days) and higher HOMA-IR later in life (age 120–122 and 190–192 days) relative to casein IUGR. This study shows the potential advantage of casein relative to whey during weaning on short term energy intake, growth, and glucose homeostasis in an IUGR model and reveals, for the first time, its long term impact on insulin sensitivity, which may have implications for later metabolic health, particularly in small-for-gestational-age populations at risk of type 2 diabetes.

Long-Term Metabolic Consequences of Intrauterine Growth Restriction

2020 ◽  
Vol 8 (2) ◽  
pp. 45-55 ◽  
Author(s):  
Kyoung Eun Joung ◽  
Jieun Lee ◽  
Jae Hyun Kim
Keyword(s):  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Intrauterine Growth

scholarly journals PERINATAL OUTCOMES AND LONG-TERM EFFECTS OF FETAL GROWTH RESTRICTION

2012 ◽  
Vol 61 (6) ◽  
pp. 68-75 ◽  
Author(s):  
Natalya Vladimirovna Artymuk ◽  
Aleksey Gennadyevich Trishkin ◽  
Ekaterina Sergeevna Bikmetova
Keyword(s):  
High Risk ◽  
Fetal Growth ◽  
Intrauterine Growth Restriction ◽  
Perinatal Outcomes ◽  
Growth Restriction ◽  
Fetal Life ◽  
Long Term Effects ◽  
Intrauterine Growth ◽  
Effects On Children

The article presents a review of sources concerning perinatal outcomes and long-term effects on children and adults born with intrauterine growth restriction (IUGR). Neonates with IUGR are at high risk for morbidity and mortality. The conditions of antenatal fetal life may program the range of unfavorable long-term effects in adulthood. This requires further study of the etiology, pathogenesis, diagnosis, and management of IUGR.

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